| Long name | Recombinant Mouse BRCA1-associated RING domain protein 1 (Bard1) |
| Alternative names | BARD-1, BRCA1 associated RING domain 1, BRCA1-associated RING domain protein 1, BRCA1-associated RING domain protein 1, BRCA1-associated RING domain protein 1 |
| Gene name | Bard1 |
| Other gene names | BARD-1, Bard1, ENSMUSG00000060893, ENSMUSG00000073653, Bard1 |
| General description | All of our recombinant proteins are manufactured in strictly controlled facilities and by using a well established technology which guarantees full batch-to-bact consistency and experiment reproducibility, The protein can be with or without a His-Tag or other tag in accordance to customer's request, BRCA1-associated RING domain protein 1 (Bard1) is a recombinant protein expressed in Baculovirus |
| Product category | Recombinant Proteins |
| Expression system | Baculovirus |
| Available also expressed in: | Baculovirus , Mammalian Cell, Yeast , E Coli |
| Purity | Greater than 90% (determined by SDS-PAGE) |
| Form | Lyophilized protein |
| Storage | Avoid cycles of freezing and thawing as they might denaturate the polypeptide chains, For extended periods of time it is recommended to keep the protein frozen at -40 or -80 degrees Celsius, This protein can be stored at -20 degrees Celsius |
| Applications | IFA, RIA, Western Blot, etc, This protein can be used as a positive control for applications such as ELISA |
| Test | A/J, BALB/c, Mouse are mature after 40 days for females and 55 days for males, SCID while the CD-1 is outbred as strain, The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year, Transgenic, congenic and inbread strains are known for C57BL/6, knock-out, Mouse , mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab, or |
| Latin name | Mus musculus |
| Gene target | BRCA1-associated RING domain protein 1 (Bard1) |
| Short name | Mouse BRCA1-associated RING domain protein 1 (Bard1) |
| Technique | mouses, Mouse |
| Species | Mouses, Mouse |
| Alternative name | early onset associated RING domain 1), early onset-associated RING domain protein 1 (breast cancer 1, Mouse breast cancer 1 |
| Alternative technique | murine |
| Alternative to gene target | BRCA1 and IDBG-52172 and ENSG00000012048 and 672, BRCA1 and IDBG-640630 and ENSBTAG00000022520 and 353120, BRCAI and BRCC1 and BROVCA1 and IRIS and PNCA4 and PPP1R53 and PSCP and RNF53, Brca1 and IDBG-212218 and ENSMUSG00000017146 and 12189, DNA-templated and biological process this GO :0045893 and positive regulation of transcription, DNA-templated and biological process this GO :0045944 and positive regulation of transcription from RNA polymerase II promoter and biological process this GO :0046600 and negative regulation of centriole replication and biological process this GO :0046872 and metal ion binding and molecular function this GO :0050681 and androgen receptor binding and molecular function this GO :0051571 and positive regulation of histone H3-K4 methylation and biological process this GO :0051572 and negative regulation of histone H3-K4 methylation and biological process this GO :0051573 and negative regulation of histone H3-K9 methylation and biological process this GO :0051574 and positive regulation of histone H3-K9 methylation and biological process this GO :0051865 and protein autoubiquitination and biological process this GO :0070512 and positive regulation of histone H4-K20 methylation and biological process this GO :0070531 and BRCA1-A complex and cellular component this GO :0071158 and positive regulation of cell cycle arrest and biological process this GO :0071681 and cellular response to indole-3-methanol and biological process this GO :0085020 and protein K6-linked ubiquitination and biological process this GO :2000145 and regulation of cell motility and biological process this GO :2000617 and positive regulation of histone H3-K9 acetylation and biological process this GO :2000620 and positive regulation of histone H4-K16 acetylation and biological process, androgen receptor binding, early onset, nuclei, signal transduction by p53 class mediator resulting in transcription of p21 class mediator and biological process this GO :0007059 and chromosome segregation and biological process this GO :0007098 and centrosome cycle and biological process this GO :0008270 and zinc ion binding and molecular function this GO :0008274 and gamma-tubulin ring complex and cellular component this GO :0008630 and intrinsic apoptotic signaling pathway in response to DNA damage and biological process this GO :0009048 and dosage compensation by inactivation of X chromosome and biological process this GO :0010212 and response to ionizing radiation and biological process this GO :0015631 and tubulin binding and molecular function this GO :0016567 and protein ubiquitination and biological process this GO :0016874 and ligase activity and molecular function this GO :0019899 and enzyme binding and molecular function this GO :0030521 and androgen receptor signaling pathway and biological process this GO :0030529 and ribonucleoprotein complex and cellular component this GO :0031398 and positive regulation of protein ubiquitination and biological process this GO :0031436 and BRCA1-BARD1 complex and cellular component this GO :0031572 and G2 DNA damage checkpoint and biological process this GO :0031625 and ubiquitin protein ligase binding and molecular function this GO :0031941 and filamentous actin and cellular component this GO :0034446 and substrate adhesion-dependent cell spreading and biological process this GO :0035066 and positive regulation of histone acetylation and biological process this GO :0035067 and negative regulation of histone acetylation and biological process this GO :0042127 and regulation of cell proliferation and biological process this GO :0042981 and regulation of apoptotic process and biological process this GO :0043009 and chordate embryonic development and biological process this GO :0043234 and protein complex and cellular component this GO :0043627 and response to estrogen and biological process this GO :0044030 and regulation of DNA methylation and biological process this GO :0044212 and transcription regulatory region DNA binding and molecular function this GO :0045717 and negative regulation of fatty acid biosynthetic process and biological process this GO :0045739 and positive regulation of DNA repair and biological process this GO :0045892 and negative regulation of transcription, this GO :0000151 and ubiquitin ligase complex and cellular component this GO :0000724 and double-strand break repair via homolo this GO us recombination and biological process this GO :0000793 and condensed chromosome and cellular component this GO :0000794 and condensed nuclear chromosome and cellular component this GO :0001726 and ruffle and cellular component this GO :0003677 and DNA binding and molecular function this GO :0003684 and damaged DNA binding and molecular function this GO :0003713 and transcription coactivator activity and molecular function this GO :0003723 and RNA binding and molecular function this GO :0004842 and ubiquitin-protein transferase activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0005654 and nucleoplasm and cellular component this GO :0005694 and chromosome and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0005925 and focal adhesion and cellular component this GO :0006260 and DNA replication and biological process this GO :0006281 and DNA repair and biological process this GO :0006301 and postreplication repair and biological process this GO :0006302 and double-strand break repair and biological process this GO :0006349 and regulation of gene expression by genetic imprinting and biological process this GO :0006357 and regulation of transcription from RNA polymerase II promoter and biological process this GO :0006359 and regulation of transcription from RNA polymerase III promoter and biological process this GO :0006633 and fatty acid biosynthetic process and biological process this GO :0006915 and apoptotic process and biological process this GO :0006974 and cellular response to DNA damage stimulus and biological process this GO :0006978 and DNA damage response, this GO :0003677: DNA binding, this GO :0003677: DNA binding and also this GO :0003684: damaged DNA binding and also this GO :0003713: transcription coactivator activity and also this GO :0003723: RNA binding and also this GO :0004842: ubiquitin-protein transferase activity and also this GO :0005515: protein binding and also this GO :0008270: zinc ion binding and also this GO :0015631: tubulin binding and also this GO :0016874: ligase activity and also this GO :0019899: enzyme binding and also this GO :0031625: ubiquitin protein ligase binding and also this GO :0044212: transcription regulatory region DNA binding and also this GO :0046872: metal ion binding and also this GO :0050681: androgen receptor binding, this GO :0003684: damaged DNA binding, this GO :0003713: transcription coactivator activity, this GO :0003723: RNA binding, this GO :0004842: ubiquitin-protein transferase activity, this GO :0005515: protein binding, this GO :0008270: zinc ion binding, this GO :0015631: tubulin binding, this GO :0016874: ligase activity, this GO :0019899: enzyme binding, this GO :0031625: ubiquitin protein ligase binding, this GO :0044212: transcription regulatory region DNA binding, this GO :0046872: metal ion binding, this GO :0050681: androgen receptor binding, breast cancer 1 |
| Identity | 1100 |
| Gene | BRCA1 |
| Long gene name | BRCA1, DNA repair associated |
| Synonyms gene name | breast cancer 1, early onset breast cancer 1 |
| Synonyms | RNF53 BRCC1 PPP1R53 FANCS |
| Synonyms name | BRCA1/BRCA2-containing complex, complementation group S , regulatory subunit 53 Fanconi anemia, subunit 1 protein phosphatase 1 |
| Locus | 17q21, 31 |
| Discovery year | 1991-02-20 |
| GenBank acession | U14680 |
| Entrez gene record | 672 |
| Pubmed identfication | 1676470 25472942 |
| RefSeq identity | NM_007294 |
| Classification | Ring finger proteins Protein phosphatase 1 regulatory subunits BRCA1 A complex BRCA1 B complex BRCA1 C complex Fanconi anemia complementation groups |
| Havana BLAST/BLAT | OTTHUMG00000157426 |
| Locus Specific Databases | Breast Cancer BRCA1 database at LOVD-China LOVD - Leiden Open Variation Database LOVD - Leiden Open Variation Database LRG_292 |
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