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mouse IL-10 Antibody

mouse IL-10 Antibody size: 0.1mg 406

Supplier NJS POLY
Price 406
Size 0.1mg
CategoryAntibody
Concentration2ml sterile DI water, 5mg/ml if reconstituted with 0
FormAntigen affinity purified
ConjugationUnconjugated
ClonePolyclonal antibody
Recognised antigenmouse IL-10
Host animalRabbit (Oryctolagus cuniculus)
ClonalityPolyclonal (rabbit origin)
Species reactivity Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur, Mouse (Mus musculus)
Tested applications ELISA, WB
Recommended dilutions1-0, 5-1ug/ml, 5ug/ml, ELISA: 0, Western blot: 0
Notes Titration of the mouse IL-10 antibody may be required due to differences in protocols and secondary/substrate sensitivity, The stated application concentrations are suggested starting amounts
Intented useThis mouse IL10 antibodyis to be used only for research purposes and not for diagnostics
Uniprot #P18893
PurityAntigen affinity
Description Eskdale et al, IL-10 also displays potent abilities to suppress the antigen presentation capacity of antigen presenting cells, IL-2, IL-3, In humans IL-10 is encoded by the IL10 gene, It is capable of inhibiting synthesis of pro-inflammatory cytokines like IFN-gamma, Kim et al, TNFalpha and GM-CSF made by cells such as macrophages and regulatory T-cells, also known as human cytokine synthesis inhibitory factor(CSIF), is an anti-inflammatory cytokine, (1992) showed that the mouse IL 10 gene contains 5 exons and spans about 5, (1997) mapped the IL10 gene to the junction between 1q31 and 1q32, 2 kb of genomic DNA, Interleukin-10
ImmunogenMouse partial recombinant protein (AA 19-178) was used as the immunogen for this mouse IL-10 antibody
Storage Avoid repeated freezing and thawing, Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, For long-term, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, aliquot and store at -20 deg, the mouse IL-10 antibody can be stored for up to one month at 4oC, After reconstitution
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°
Gene targetIL-10
Short namemouse IL-10 Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Hostmouse
Alternative namemouse Interleukin-10 (Antibody to)
Alternative techniqueantibodies
Identity 5962
Gene IL10
Long gene name interleukin 10
Synonyms CSIF TGIF IL10A IL-10
Synonyms name cytokine synthesis inhibitory factor T-cell growth inhibitory factor
Locus 1q32, 1
Discovery year 1991-10-31
GenBank acession M57627
Entrez gene record 3586
Pubmed identfication 9162098
RefSeq identity NM_000572
Classification Interleukins
Havana BLAST/BLAT OTTHUMG00000036386

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