Name : mouse IL-10 Antibody
Supplier : NJS POLY
Price :406
SKU : GEN9987179234
| Category | Antibody |
| Concentration | 2ml sterile DI water, 5mg/ml if reconstituted with 0 |
| Form | Antigen affinity purified |
| Conjugation | Unconjugated |
| Clone | Polyclonal antibody |
| Recognised antigen | mouse IL-10 |
| Host animal | Rabbit (Oryctolagus cuniculus) |
| Clonality | Polyclonal (rabbit origin) |
| Species reactivity | Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur, Mouse (Mus musculus) |
| Tested applications | ELISA, WB |
| Recommended dilutions | 1-0, 5-1ug/ml, 5ug/ml, ELISA: 0, Western blot: 0 |
| Notes | Titration of the mouse IL-10 antibody may be required due to differences in protocols and secondary/substrate sensitivity, The stated application concentrations are suggested starting amounts |
| Intented use | This mouse IL10 antibodyis to be used only for research purposes and not for diagnostics |
| Uniprot # | P18893 |
| Purity | Antigen affinity |
| Description | Eskdale et al, IL-10 also displays potent abilities to suppress the antigen presentation capacity of antigen presenting cells, IL-2, IL-3, In humans IL-10 is encoded by the IL10 gene, It is capable of inhibiting synthesis of pro-inflammatory cytokines like IFN-gamma, Kim et al, TNFalpha and GM-CSF made by cells such as macrophages and regulatory T-cells, also known as human cytokine synthesis inhibitory factor(CSIF), is an anti-inflammatory cytokine, (1992) showed that the mouse IL 10 gene contains 5 exons and spans about 5, (1997) mapped the IL10 gene to the junction between 1q31 and 1q32, 2 kb of genomic DNA, Interleukin-10 |
| Immunogen | Mouse partial recombinant protein (AA 19-178) was used as the immunogen for this mouse IL-10 antibody |
| Storage | Avoid repeated freezing and thawing, Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, For long-term, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, aliquot and store at -20 deg, the mouse IL-10 antibody can be stored for up to one month at 4oC, After reconstitution |
| Properties | C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target | IL-10 |
| Short name | mouse IL-10 Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Host | mouse |
| Alternative name | mouse Interleukin-10 (Antibody to) |
| Alternative technique | antibodies |
| Identity | 5962 |
| Gene | IL10 |
| Long gene name | interleukin 10 |
| Synonyms | CSIF TGIF IL10A IL-10 |
| Synonyms name | cytokine synthesis inhibitory factor T-cell growth inhibitory factor |
| Locus | 1q32, 1 |
| Discovery year | 1991-10-31 |
| GenBank acession | M57627 |
| Entrez gene record | 3586 |
| Pubmed identfication | 9162098 |
| RefSeq identity | NM_000572 |
| Classification | Interleukins |
| Havana BLAST/BLAT | OTTHUMG00000036386 |