| Also known as | NEUROD1 / Beta2 |
| Other names | Class A basic helix-loop-helix protein 3, Neurogenic differentiation factor 1, bHLHa3, basic helix-loop-helix transcription factor, beta-cell E-box transactivator 2, class A basic helix-loop-helix protein 3, neurogenic differentiation factor 1, neurogenic helix-loop-helix protein NEUROD, neuronal differentiation 1, neurogenic differentiation factor 1 |
| Category | Antibodies |
| Subcategory | Mnoclonal antibodies |
| Gene name | NEUROD1 |
| Gene name synonims | N/A |
| Other gene names | BETA2, BHF-1, BHLHA3, MODY6, NEUROD, NEUROD, NEUROD1, NeuroD, NeuroD1, bHLHa3, bHLHa3, NEUROD1 |
| Clonality | Monoclonal |
| Immunoglobulin isotype | IgG |
| Clone | 3D11 |
| Host organism | Mouse (Mus musculus) |
| Species reactivity | Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby, Human (Homo sapiens) |
| Specificity and cross-reactivity | Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited, This particular antibody might cross react with speacies outside of the listed ones, Human NeuroD1 |
| Purification method | Protein A Purified |
| Form/Appearance | pH 7, 2, PBS |
| Concentration | 5 mg/ml |
| Storage and shipping | For long term storage aliquot and keep the antibody at -20 degrees Celsius, Freeze-thaw cycles should be avoided in order to retain the activity of the antibody, Store at +4 degrees Celsius for short term storage |
| Tested applications: | ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC - Paraffin) |
| Properties | Depending on the epitopes used human ELISA kits can be cross reactive to many other species, Human proteins, Mainly analyzed are human serum, Modern , cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies, human cell culture supernatants and biological samples, plasma, primarily , saliva, urine, , (Homo sapiens, C, C for long term storage and for short term at + 5°, Homo sapiens sapiens), If you buy Antibodies supplied by MBS mono they should be stored frozen at - 24°, humans , ssp |
| About | 2 light chains, Each murine monoclonal anibody has his own affinity specific for the clone, For storage sodium azide is added or you can call us to request azide free antibody preparations, IgG, Monoclonals of this antigen are available in different clones, Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes, The IgG antibody has 2 , There are 2 heavy chains, These will need colder storage temperatures, They represent 70% or more of , This antibody can be antigen purified or protein A or G purified, goat polyclonal antibodies , mouse monoclonal H&, Immunoglobulin gamma, L chain clones or rabbit, antibodies, antigen , binding sites, have 4 parts, serum |
| Test | A/J, BALB/c, Mouse are mature after 40 days for females and 55 days for males, SCID while the CD-1 is outbred as strain, The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year, Transgenic, congenic and inbread strains are known for C57BL/6, knock-out, Mouse , mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab, or |
| Latin name | Mus musculus |
| Gene target | Monoclonal [ 3D11] NEUROD1 / Beta2 |
| Short name | Mouse Monoclonal [clone 3D11] (IgG) NEUROD1 / Beta2 Antibody |
| Technique | IgGs, Monoclonals or monoclonal antibodies, antibodies against human proteins, antibodies for, mouses, Antibody |
| Isotype | IgG |
| Species | Humans, Mouses, Human |
| Alternative name | sapiens neuronal differentiation 1 / Beta2 (Antibody to), Mouse monoclonal [clonality 3D11] (Immunoglobulin G) to H |
| Alternative technique | antibodies |
| Alternative to gene target | BETA2 and BHF-1 and bHLHa3 and MODY6 and NEUROD, BT, DNA-templated and biological process this GO :0006913 and nucleocytoplasmic transport and biological process this GO :0007263 and nitric oxide mediated signal transduction and biological process this GO :0008134 and transcription factor binding and molecular function this GO :0009749 and response to glucose and biological process this GO :0009952 and anterior/posterior pattern specification and biological process this GO :0021542 and dentate gyrus development and biological process this GO :0021549 and cerebellum development and biological process this GO :0022008 and neurogenesis and biological process this GO :0023019 and signal transduction involved in regulation of gene expression and biological process this GO :0030073 and insulin secretion and biological process this GO :0030902 and hindbrain development and biological process this GO :0031018 and endocrine pancreas development and biological process this GO :0035881 and amacrine cell differentiation and biological process this GO :0035883 and enteroendocrine cell differentiation and biological process this GO :0042493 and response to drug and biological process this GO :0042593 and glucose homeostasis and biological process this GO :0043010 and camera-type eye development and biological process this GO :0043065 and positive regulation of apoptotic process and biological process this GO :0043565 and sequence-specific DNA binding and molecular function this GO :0045165 and cell fate commitment and biological process this GO :0045597 and positive regulation of cell differentiation and biological process this GO :0045664 and regulation of neuron differentiation and biological process this GO :0045666 and positive regulation of neuron differentiation and biological process this GO :0045893 and positive regulation of transcription, DNA-templated and biological process this GO :0045944 and positive regulation of transcription from RNA polymerase II promoter and biological process this GO :0046426 and negative regulation of JAK-STAT cascade and biological process this GO :0046982 and protein heterodimerization activity and molecular function this GO :0046983 and protein dimerization activity and molecular function this GO :0048562 and embryonic organ morphogenesis and biological process this GO :0048839 and inner ear development and biological process this GO :0050796 and regulation of insulin secretion and biological process this GO :0051091 and positive regulation of sequence-specific DNA binding transcription factor activity and biological process this GO :0060730 and regulation of intestinal epithelial structure maintenance and biological process this GO :0070888 and E-box binding and molecular function this GO :0071156 and regulation of cell cycle arrest and biological process this GO :0071333 and cellular response to glucose stimulus and biological process this GO :2000675 and negative regulation of type B pancreatic cell apoptotic process and biological process this GO :2000679 and positive regulation of transcription regulatory region DNA binding and biological process, E-box binding, NEUROD1 and IDBG-76792 and ENSG00000162992 and 4760, Neurod1 and IDBG-183353 and ENSMUSG00000034701 and 18012, nuclei, this GO :0000978 and RNA polymerase II core promoter proximal region sequence-specific DNA binding and molecular function this GO :0001077 and RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription and molecular function this GO :0001102 and RNA polymerase II activating transcription factor binding and molecular function this GO :0001105 and RNA polymerase II transcription coactivator activity and molecular function this GO :0003326 and pancreatic A cell fate commitment and biological process this GO :0003329 and pancreatic PP cell fate commitment and biological process this GO :0003677 and DNA binding and molecular function this GO :0003682 and chromatin binding and molecular function this GO :0003690 and double-stranded DNA binding and molecular function this GO :0003700 and sequence-specific DNA binding transcription factor activity and molecular function this GO :0003713 and transcription coactivator activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005622 and intracellular and cellular component this GO :0005634 and nucleus and cellular component this GO :0005654 and nucleoplasm and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0006351 and transcription, this GO :0000978: RNA polymerase II core promoter proximal region sequence-specific DNA binding, this GO :0000978: RNA polymerase II core promoter proximal region sequence-specific DNA binding and also this GO :0001077: RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription and also this GO :0001102: RNA polymerase II activating transcription factor binding and also this GO :0001105: RNA polymerase II transcription coactivator activity and also this GO :0003677: DNA binding and also this GO :0003682: chromatin binding and also this GO :0003690: double-stranded DNA binding and also this GO :0003700: sequence-specific DNA binding transcription factor activity and also this GO :0003713: transcription coactivator activity and also this GO :0005515: protein binding and also this GO :0008134: transcription factor binding and also this GO :0043565: sequence-specific DNA binding and also this GO :0046982: protein heterodimerization activity and also this GO :0046983: protein dimerization activity and also this GO :0070888: E-box binding, this GO :0001077: RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription, this GO :0001102: RNA polymerase II activating transcription factor binding, this GO :0001105: RNA polymerase II transcription coactivator activity, this GO :0003677: DNA binding, this GO :0003682: chromatin binding, this GO :0003690: double-stranded DNA binding, this GO :0003700: sequence-specific DNA binding transcription factor activity, this GO :0003713: transcription coactivator activity, this GO :0005515: protein binding, this GO :0008134: transcription factor binding, this GO :0043565: sequence-specific DNA binding, this GO :0046982: protein heterodimerization activity, this GO :0046983: protein dimerization activity, this GO :0070888: E-box binding, 104022 and IDBG-648841 and ENSBTAG00000001755 and 539487, neuronal differentiation 1 |
| Identity | 7762 |
| Gene | NEUROD1 |
| Long gene name | neuronal differentiation 1 |
| Synonyms gene | NEUROD |
| Synonyms gene name | neurogenic differentiation 1 |
| Synonyms | BETA2 BHF-1 NeuroD bHLHa3 MODY6 |
| Synonyms name | beta-cell E-box transactivator 2 neurogenic helix-loop-helix protein NEUROD |
| Locus | 2q31, 3 |
| Discovery year | 1996-03-12 |
| GenBank acession | U50823 |
| Entrez gene record | 4760 |
| Pubmed identfication | 7754368 8786144 |
| RefSeq identity | NM_002500 |
| Classification | Basic helix-loop-helix proteins |
| Havana BLAST/BLAT | OTTHUMG00000132583 |
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