| Also known as | CYR61 |
| Other names | 61, 61, CCN family member 1, CCN family member 1, Cysteine-rich angiogenic inducer 61, IBP-10, IBP-10, IGF-binding protein 10, IGF-binding protein 10, IGFBP-10, IGFBP-10, Insulin-like growth factor-binding protein 10, Protein CYR61, Protein GIG1, angiogenic inducer, anigogenic inducer, cysteine-rich, cysteine-rich, cysteine-rich heparin-binding protein 61, insulin-like growth factor-binding protein 10, protein CYR61, protein CYR61 |
| Category | Antibodies |
| Subcategory | Mnoclonal antibodies |
| Gene name | CYR61 |
| Gene name synonims | N/A |
| Other gene names | CCN1, CCN1, CYR61, GIG1, GIG1, IBP-10, IGF-binding protein 10, IGFBP-10, IGFBP10, IGFBP10, CYR61 |
| Clonality | Monoclonal |
| Immunoglobulin isotype | IgG1, k |
| Clone | 3H3 |
| Host organism | Mouse (Mus musculus) |
| Species reactivity | Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby, Human (Homo sapiens) |
| Specificity and cross-reactivity | Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited, This particular antibody might cross react with speacies outside of the listed ones, N/A |
| Purification method | Protein G Purified |
| Form/Appearance | 0, Sourced in Ascites, pH 7, 1% sodium azide, 4, PBS |
| Concentration | 1 miligram per 1 mililiter |
| Storage and shipping | Cycles of freezing/defrosting can damage the peptide chains of the antibodies thus reducing the activity, Short term storage of the antibody can be done at +4 degrees Celsius, keep the antibody at -20 degrees Celsius, For long term storage |
| Tested applications: | ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC - Paraffin) |
| Properties | Depending on the epitopes used human ELISA kits can be cross reactive to many other species, Human proteins, Mainly analyzed are human serum, Modern , cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies, human cell culture supernatants and biological samples, plasma, primarily , saliva, urine, , (Homo sapiens, C, C for long term storage and for short term at + 5°, Homo sapiens sapiens), If you buy Antibodies supplied by MBS mono they should be stored frozen at - 24°, humans , ssp |
| About | Each murine monoclonal anibody has his own affinity specific for the clone, Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes, Monoclonals of this antigen are available in different clones |
| Test | A/J, BALB/c, Mouse are mature after 40 days for females and 55 days for males, SCID while the CD-1 is outbred as strain, The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year, Transgenic, congenic and inbread strains are known for C57BL/6, knock-out, Mouse , mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab, or |
| Latin name | Mus musculus |
| Gene target | Monoclonal [ 3H3] (IgG1, k) CYR61 |
| Short name | Mouse Monoclonal [clone 3H3] (IgG1, k) CYR61 Antibody |
| Technique | Monoclonals or monoclonal antibodies, antibodies against human proteins, antibodies for, mouses, Antibody |
| Isotype | IgG1 |
| Species | Humans, Mouses, Human |
| Alternative name | 61 (Antibody to), angiogenic inducer, sapiens cysteine-rich, Mouse monoclonal [clonality 3H3] (IgG1, k) to H |
| Alternative technique | antibodies |
| Alternative to gene target | 61, CCN1 and GIG1 and IGFBP10, CYR61 and IDBG-100054 and ENSG00000142871 and 3491, CYR61 and IDBG-637282 and ENSBTAG00000009844 and 508941, Cyr61 and IDBG-198706 and ENSMUSG00000028195 and 16007, Extracellular, angiogenic inducer, extracellular matrix binding, spreading of cells and biological process this GO :0045597 and positive regulation of cell differentiation and biological process this GO :0045669 and positive regulation of osteoblast differentiation and biological process this GO :0045860 and positive regulation of protein kinase activity and biological process this GO :0045944 and positive regulation of transcription from RNA polymerase II promoter and biological process this GO :0050840 and extracellular matrix binding and molecular function this GO :0060413 and atrial septum morphogenesis and biological process this GO :0060591 and chondroblast differentiation and biological process this GO :0060710 and chorio-allantoic fusion and biological process this GO :0060716 and labyrinthine layer blood vessel development and biological process this GO :0061036 and positive regulation of cartilage development and biological process this GO :0070372 and regulation of ERK1 and ERK2 cascade and biological process this GO :0072593 and reactive oxygen species metabolic process and biological process this GO :2000304 and positive regulation of ceramide biosynthetic process and biological process, this GO :0001558 and regulation of cell growth and biological process this GO :0001649 and osteoblast differentiation and biological process this GO :0001934 and positive regulation of protein phosphorylation and biological process this GO :0002041 and intussusceptive angiogenesis and biological process this GO :0003181 and atrioventricular valve morphogenesis and biological process this GO :0003278 and apoptotic process involved in heart morphogenesis and biological process this GO :0003281 and ventricular septum development and biological process this GO :0005178 and integrin binding and molecular function this GO :0005515 and protein binding and molecular function this GO :0005520 and insulin-like growth factor binding and molecular function this GO :0005576 and extracellular region and cellular component this GO :0006935 and chemotaxis and biological process this GO :0007155 and cell adhesion and biological process this GO :0008201 and heparin binding and molecular function this GO :0008283 and cell proliferation and biological process this GO :0009653 and anatomical structure morphogenesis and biological process this GO :0010518 and positive regulation of phospholipase activity and biological process this GO :0010811 and positive regulation of cell-substrate adhesion and biological process this GO :0016337 and single organismal cell-cell adhesion and biological process this GO :0030198 and extracellular matrix organization and biological process this GO :0030335 and positive regulation of cell migration and biological process this GO :0030513 and positive regulation of BMP signaling pathway and biological process this GO :0033690 and positive regulation of osteoblast proliferation and biological process this GO :0043065 and positive regulation of apoptotic process and biological process this GO :0043066 and negative regulation of apoptotic process and biological process this GO :0043280 and positive regulation of cysteine-type endopeptidase activity involved in apoptotic process and biological process this GO :0044319 and wound healing, this GO :0005178: integrin binding, this GO :0005178: integrin binding and also this GO :0005515: protein binding and also this GO :0005520: insulin-like growth factor binding and also this GO :0008201: heparin binding and also this GO :0050840: extracellular matrix binding, this GO :0005515: protein binding, this GO :0005520: insulin-like growth factor binding, this GO :0008201: heparin binding, this GO :0050840: extracellular matrix binding, cysteine-rich |
| Identity | 2654 |
| Gene | CYR61 |
| Long gene name | cysteine rich angiogenic inducer 61 |
| Synonyms gene | IGFBP10 |
| Synonyms gene name | 61 , angiogenic inducer, cysteine-rich |
| Synonyms | GIG1 CCN1 |
| Locus | 1p22, 3 |
| Discovery year | 1998-03-02 |
| GenBank acession | AF031385 |
| Entrez gene record | 3491 |
| Pubmed identfication | 9135077 |
| RefSeq identity | NM_001554 |
| Classification | CYR61/CTGF/NOV matricellular proteins |
| Havana BLAST/BLAT | OTTHUMG00000010577 |
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