| Also known as | ITGB3 / Integrin Beta 3 / CD61 |
| Other names | CD_antigen: CD61, GPIIIa, Integrin beta-3, Platelet membrane glycoprotein IIIa, antigen CD61), beta 3 (platelet glycoprotein IIIa, integrin, integrin beta-3, platelet membrane glycoprotein IIIa, integrin beta-3 |
| Category | Antibodies |
| Subcategory | Mnoclonal antibodies |
| Gene name | ITGB3 |
| Gene name synonims | N/A |
| Other gene names | BDPLT16, BDPLT2, CD61, GP3A, GP3A, GPIIIa, GPIIIa, GT, ITGB3, ITGB3 |
| Clonality | Monoclonal |
| Immunoglobulin isotype | IgG1, k |
| Clone | VI-PL2 |
| Host organism | Mouse (Mus musculus) |
| Species reactivity | Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby, Human (Homo sapiens) |
| Specificity and cross-reactivity | Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited, This particular antibody might cross react with speacies outside of the listed ones, N/A |
| Purification method | Affinity Purified |
| Form/Appearance | <, pH 7, 09% sodium azide, 2, =0, PBS |
| Concentration | 5 mg/ml |
| Storage and shipping | avoid repeated freeze thaw cycles, Store the antibody at +4 degrees Celsius |
| Tested applications: | Flow Cytometry (FC/FACS), IHC - Frozen), Western Blot (WB), Immunohistochemistry (IHC - Paraffin |
| Properties | Depending on the epitopes used human ELISA kits can be cross reactive to many other species, Human proteins, Mainly analyzed are human serum, Modern , cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies, human cell culture supernatants and biological samples, plasma, primarily , saliva, urine, , (Homo sapiens, C, C for long term storage and for short term at + 5°, Homo sapiens sapiens), If you buy Antibodies supplied by MBS mono they should be stored frozen at - 24°, humans , ssp |
| About | Each murine monoclonal anibody has his own affinity specific for the clone, Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes, Monoclonals of this antigen are available in different clones |
| Test | A/J, BALB/c, Mouse are mature after 40 days for females and 55 days for males, SCID while the CD-1 is outbred as strain, The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year, Transgenic, congenic and inbread strains are known for C57BL/6, knock-out, Mouse , mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab, or |
| Latin name | Mus musculus |
| Gene target | Monoclonal [ VI-PL2] (IgG1, k) ITGB3 / Integrin Beta 3 / CD61 |
| Short name | Mouse Monoclonal [clone VI-PL2] (IgG1, k) ITGB3 / Integrin Beta 3 / CD61 Antibody |
| Technique | Monoclonals or monoclonal antibodies, antibodies against human proteins, antibodies for, mouses, Antibody |
| Isotype | IgG1 |
| Species | Humans, Mouses, Human |
| Alternative name | antigen CD61) / Integrin b 3 / CD61 (Antibody to), b 3 (platelet glycoprotein IIIa, sapiens integrin, Mouse monoclonal [clonality VI-PL2] (IgG1, k) to H |
| Alternative technique | antibodies |
| Alternative to gene target | BDPLT16 and BDPLT2 and CD61 and GP3A and GPIIIa and GT, ITGB3 and IDBG-547297 and ENSG00000259207 and 3690, antigen CD61), beta 3 (platelet glycoprotein IIIa, cell adhesion molecule binding, nuclei, this GO :0001934 and positive regulation of protein phosphorylation and biological process this GO :0001938 and positive regulation of endothelial cell proliferation and biological process this GO :0002576 and platelet degranulation and biological process this GO :0003756 and protein disulfide isomerase activity and molecular function this GO :0004872 and receptor activity and molecular function this GO :0005161 and platelet-derived growth factor receptor binding and molecular function this GO :0005515 and protein binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0005887 and integral component of plasma membrane and cellular component this GO :0005925 and focal adhesion and cellular component this GO :0006457 and protein folding and biological process this GO :0007044 and cell-substrate junction assembly and biological process this GO :0007155 and cell adhesion and biological process this GO :0007160 and cell-matrix adhesion and biological process this GO :0007229 and integrin-mediated signaling pathway and biological process this GO :0007275 and multicellular organismal development and biological process this GO :0007411 and axon guidance and biological process this GO :0007596 and blood coagulation and biological process this GO :0008305 and integrin complex and cellular component this GO :0009986 and cell surface and cellular component this GO :0010595 and positive regulation of endothelial cell migration and biological process this GO :0010745 and negative regulation of macrophage derived foam cell differentiation and biological process this GO :0010888 and negative regulation of lipid storage and biological process this GO :0014909 and smooth muscle cell migration and biological process this GO :0016020 and membrane and cellular component this GO :0016032 and viral process and biological process this GO :0030168 and platelet activation and biological process this GO :0030198 and extracellular matrix organization and biological process this GO :0030334 and regulation of cell migration and biological process this GO :0030949 and positive regulation of vascular endothelial growth factor receptor signaling pathway and biological process this GO :0031092 and platelet alpha granule membrane and cellular component this GO :0031258 and lamellipodium membrane and cellular component this GO :0031589 and cell-substrate adhesion and biological process this GO :0032147 and activation of protein kinase activity and biological process this GO :0032369 and negative regulation of lipid transport and biological process this GO :0035295 and tube development and biological process this GO :0042060 and wound healing and biological process this GO :0042470 and melanosome and cellular component this GO :0042802 and identical protein binding and molecular function this GO :0043184 and vascular endothelial growth factor receptor 2 binding and molecular function this GO :0043235 and receptor complex and cellular component this GO :0045087 and innate immune response and biological process this GO :0045124 and regulation of bone resorption and biological process this GO :0045715 and negative regulation of low-density lipoprotein particle receptor biosynthetic process and biological process this GO :0050731 and positive regulation of peptidyl-tyrosine phosphorylation and biological process this GO :0050748 and negative regulation of lipoprotein metabolic process and biological process this GO :0050839 and cell adhesion molecule binding and molecular function this GO :0050900 and leukocyte migration and biological process this GO :0060055 and angiogenesis involved in wound healing and biological process this GO :0070062 and extracellular vesicular exosome and cellular component this GO :0070527 and platelet aggregation and biological process this GO :0071062 and alphav-beta3 integrin-vitronectin complex and cellular component, this GO :0003756: protein disulfide isomerase activity, this GO :0003756: protein disulfide isomerase activity and also this GO :0004872: receptor activity and also this GO :0005161: platelet-derived growth factor receptor binding and also this GO :0005515: protein binding and also this GO :0042802: identical protein binding and also this GO :0043184: vascular endothelial growth factor receptor 2 binding and also this GO :0050839: cell adhesion molecule binding, this GO :0004872: receptor activity, this GO :0005161: platelet-derived growth factor receptor binding, this GO :0005515: protein binding, this GO :0042802: identical protein binding, this GO :0043184: vascular endothelial growth factor receptor 2 binding, this GO :0050839: cell adhesion molecule binding, integrin |
| Identity | 6156 |
| Gene | ITGB3 |
| Long gene name | integrin subunit beta 3 |
| Synonyms gene | GP3A |
| Synonyms gene name | antigen CD61) , beta 3 (platelet glycoprotein IIIa, integrin |
| Synonyms | CD61 GPIIIa |
| Synonyms name | platelet glycoprotein IIIa antigen CD61 |
| Locus | 17q21, 32 |
| Discovery year | 1988-06-09 |
| Entrez gene record | 3690 |
| Pubmed identfication | 2454952 |
| RefSeq identity | NM_000212 |
| Classification | Integrin beta subunits CD molecules |
| Havana BLAST/BLAT | OTTHUMG00000171956 |
| Locus Specific Databases | LRG_481 |
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