| Also known as | MKP3 / DUSP6 |
| Other names | Dual specificity protein phosphatase 6, Dual specificity protein phosphatase PYST1, MAP kinase phosphatase 3, MAP kinase phosphatase 3, MKP-3, Mitogen-activated protein kinase phosphatase 3, dual specificity phosphatase 6, dual specificity protein phosphatase 6, dual specificity protein phosphatase PYST1, mitogen-activated protein kinase phosphatase 3, serine/threonine specific protein phosphatase, dual specificity protein phosphatase 6 isoform a |
| Category | Antibodies |
| Subcategory | Mnoclonal antibodies |
| Gene name | MKP3 |
| Gene name synonims | DUSP6 |
| Other gene names | DUSP6, HH19, MAP kinase phosphatase 3, MKP-3, MKP3, MKP3, PYST1, PYST1, DUSP6 |
| Clonality | Monoclonal |
| Immunoglobulin isotype | IgG1, k |
| Clone | 3G2 |
| Host organism | Mouse (Mus musculus) |
| Species reactivity | Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby, Human (Homo sapiens) |
| Specificity and cross-reactivity | Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited, This particular antibody might cross react with speacies outside of the listed ones, N/A |
| Purification method | Protein A Purified |
| Form/Appearance | pH 7, 2, PBS |
| Concentration | N/A |
| Storage and shipping | We strongly recommend to avoid freeze/thaw cycles in order to keep the activity of the antibody maximally unchanged, the antibody should be kept at -20 degrees Celsius, For optimal long term storage |
| Tested applications: | ELISA (EIA), Immunofluorescence (IF), RNA interference, Western Blot (WB), Immunohistochemistry (IHC - Paraffin) |
| Properties | Depending on the epitopes used human ELISA kits can be cross reactive to many other species, Human proteins, Mainly analyzed are human serum, Modern , cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies, human cell culture supernatants and biological samples, plasma, primarily , saliva, urine, , (Homo sapiens, C, C for long term storage and for short term at + 5°, Homo sapiens sapiens), If you buy Antibodies supplied by MBS mono they should be stored frozen at - 24°, humans , ssp |
| About | Each murine monoclonal anibody has his own affinity specific for the clone, Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes, Monoclonals of this antigen are available in different clones |
| Test | A/J, BALB/c, Mouse are mature after 40 days for females and 55 days for males, SCID while the CD-1 is outbred as strain, The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year, Transgenic, congenic and inbread strains are known for C57BL/6, knock-out, Mouse , mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab, or |
| Latin name | Mus musculus |
| Gene target | Monoclonal [ 3G2] (IgG1, k) MKP3 / DUSP6 |
| Short name | Mouse Monoclonal [clone 3G2] (IgG1, k) MKP3 / DUSP6 Antibody |
| Technique | Monoclonals or monoclonal antibodies, antibodies against human proteins, antibodies for, mouses, Antibody |
| Isotype | IgG1 |
| Species | Humans, Mouses, Human |
| Alternative name | sapiens MKP3 / dual specificity phosphatase 6 (Antibody to), Mouse monoclonal [clonality 3G2] (IgG1, k) to H |
| Alternative technique | antibodies |
| Alternative to gene target | DUSP6 and IDBG-50524 and ENSG00000139318 and 1848, DUSP6 and IDBG-630730 and ENSBTAG00000004587 and 515310, Dusp6 and IDBG-187794 and ENSMUSG00000019960 and 67603, HH19 and MKP3 and PYST1, MAP kinase tyrosine/serine/threonine phosphatase activity, nuclei, this GO :0000188 and inactivation of MAPK activity and biological process this GO :0001933 and negative regulation of protein phosphorylation and biological process this GO :0002224 and toll-like receptor signaling pathway and biological process this GO :0002755 and MyD88-dependent toll-like receptor signaling pathway and biological process this GO :0002756 and MyD88-independent toll-like receptor signaling pathway and biological process this GO :0004721 and phosphoprotein phosphatase activity and molecular function this GO :0004725 and protein tyrosine phosphatase activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005654 and nucleoplasm and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0005829 and cytosol and cellular component this GO :0006470 and protein dephosphorylation and biological process this GO :0008138 and protein tyrosine/serine/threonine phosphatase activity and molecular function this GO :0009953 and dorsal/ventral pattern formation and biological process this GO :0010033 and response to organic substance and biological process this GO :0010942 and positive regulation of cell death and biological process this GO :0014070 and response to organic cyclic compound and biological process this GO :0016311 and dephosphorylation and biological process this GO :0016791 and phosphatase activity and molecular function this GO :0017017 and MAP kinase tyrosine/serine/threonine phosphatase activity and molecular function this GO :0030154 and cell differentiation and biological process this GO :0034134 and toll-like receptor 2 signaling pathway and biological process this GO :0034138 and toll-like receptor 3 signaling pathway and biological process this GO :0034142 and toll-like receptor 4 signaling pathway and biological process this GO :0034146 and toll-like receptor 5 signaling pathway and biological process this GO :0034162 and toll-like receptor 9 signaling pathway and biological process this GO :0034166 and toll-like receptor 10 signaling pathway and biological process this GO :0035335 and peptidyl-tyrosine dephosphorylation and biological process this GO :0035666 and TRIF-dependent toll-like receptor signaling pathway and biological process this GO :0038123 and toll-like receptor TLR1:TLR2 signaling pathway and biological process this GO :0038124 and toll-like receptor TLR6:TLR2 signaling pathway and biological process this GO :0040036 and regulation of fibroblast growth factor receptor signaling pathway and biological process this GO :0042493 and response to drug and biological process this GO :0042663 and regulation of endodermal cell fate specification and biological process this GO :0043065 and positive regulation of apoptotic process and biological process this GO :0045087 and innate immune response and biological process this GO :0048011 and neurotrophin TRK receptor signaling pathway and biological process this GO :0051403 and stress-activated MAPK cascade and biological process this GO :0051409 and response to nitrosative stress and biological process this GO :0060420 and regulation of heart growth and biological process this GO :0070373 and negative regulation of ERK1 and ERK2 cascade and biological process this GO :0070848 and response to growth factor and biological process, this GO :0004721: phosphoprotein phosphatase activity, this GO :0004721: phosphoprotein phosphatase activity and also this GO :0004725: protein tyrosine phosphatase activity and also this GO :0005515: protein binding and also this GO :0008138: protein tyrosine/serine/threonine phosphatase activity and also this GO :0016791: phosphatase activity and also this GO :0017017: MAP kinase tyrosine/serine/threonine phosphatase activity, this GO :0004725: protein tyrosine phosphatase activity, this GO :0005515: protein binding, this GO :0008138: protein tyrosine/serine/threonine phosphatase activity, this GO :0016791: phosphatase activity, this GO :0017017: MAP kinase tyrosine/serine/threonine phosphatase activity, dual specificity phosphatase 6 |
| Identity | 3072 |
| Gene | DUSP6 |
| Long gene name | dual specificity phosphatase 6 |
| Synonyms | MKP-3 PYST1 |
| Locus | 12q21, 33 |
| Discovery year | 1997-03-19 |
| GenBank acession | BC037236 |
| Entrez gene record | 1848 |
| Pubmed identfication | 8626780 9205128 |
| RefSeq identity | NM_001946 NM_022652 |
| Classification | MAP kinase phosphatases |
| Havana BLAST/BLAT | OTTHUMG00000169912 |
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