| Also known as | ROCK2 |
| Other names | ROCK-II, Rho kinase 2, Rho-associated, Rho-associated, Rho-associated, Rho-associated protein kinase 2, coiled-coil containing protein kinase 2, coiled-coil-containing protein kinase 2, coiled-coil-containing protein kinase II, coiled-coil-containing protein kinase II, p164 ROCK-2, p164 ROCK-2, rho-associated, rho-associated protein kinase 2, rho-associated protein kinase 2 |
| Category | Antibodies |
| Subcategory | Mnoclonal antibodies |
| Gene name | ROCK2 |
| Gene name synonims | N/A |
| Other gene names | KIAA0619, ROCK-II, ROCK-II, ROCK2, ROCK2 |
| Clonality | Monoclonal |
| Immunoglobulin isotype | IgG1, k |
| Clone | 1000000000000 |
| Host organism | Mouse (Mus musculus) |
| Species reactivity | Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby, Human (Homo sapiens) |
| Specificity and cross-reactivity | Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited, This particular antibody might cross react with speacies outside of the listed ones, N/A |
| Purification method | Protein A Purified |
| Form/Appearance | pH 7, 4, PBS |
| Concentration | 5 mg/ml |
| Storage and shipping | We strongly recommend to avoid freeze/thaw cycles in order to keep the activity of the antibody maximally unchanged, the antibody should be kept at -20 degrees Celsius, For optimal long term storage |
| Tested applications: | ELISA (EIA), Immunofluorescence (IF), Western Blot (WB), Immunohistochemistry (IHC - Paraffin) |
| Properties | Depending on the epitopes used human ELISA kits can be cross reactive to many other species, Human proteins, Mainly analyzed are human serum, Modern , cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies, human cell culture supernatants and biological samples, plasma, primarily , saliva, urine, , (Homo sapiens, C, C for long term storage and for short term at + 5°, Homo sapiens sapiens), If you buy Antibodies supplied by MBS mono they should be stored frozen at - 24°, humans , ssp |
| About | Each murine monoclonal anibody has his own affinity specific for the clone, Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes, Monoclonals of this antigen are available in different clones |
| Test | A/J, BALB/c, Mouse are mature after 40 days for females and 55 days for males, SCID while the CD-1 is outbred as strain, The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year, Transgenic, congenic and inbread strains are known for C57BL/6, knock-out, Mouse , mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab, or |
| Latin name | Mus musculus |
| Gene target | Monoclonal [ 1E12] (IgG1, k) ROCK2 |
| Short name | Mouse Monoclonal [clone 1E12] (IgG1, k) ROCK2 Antibody |
| Technique | Monoclonals or monoclonal antibodies, antibodies against human proteins, antibodies for, mouses, Antibody |
| Isotype | IgG1 |
| Species | Humans, Mouses, Human |
| Alternative name | coiled-coil containing protein kinase 2 (Antibody to), sapiens Rho-associated, Mouse monoclonal [clonality 1E12] (IgG1, k) to H |
| Alternative technique | antibodies |
| Alternative to gene target | ROCK-II, ROCK2 and IDBG-29657 and ENSG00000134318 and 9475, ROCK2 and IDBG-638012 and ENSBTAG00000005847 and 282041, Rock2 and IDBG-129486 and ENSMUSG00000020580 and 19878, coiled-coil containing protein kinase 2, nuclei, this GO :0000166 and nucleotide binding and molecular function this GO :0000910 and cytokinesis and biological process this GO :0001843 and neural tube closure and biological process this GO :0004672 and protein kinase activity and molecular function this GO :0004674 and protein serine/threonine kinase activity and molecular function this GO :0004713 and protein tyrosine kinase activity and molecular function this GO :0005198 and structural molecule activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005524 and ATP binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0005813 and centrosome and cellular component this GO :0005829 and cytosol and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0006468 and protein phosphorylation and biological process this GO :0006939 and smooth muscle contraction and biological process this GO :0007411 and axon guidance and biological process this GO :0008625 and extrinsic apoptotic signaling pathway via death domain receptors and biological process this GO :0010825 and positive regulation of centrosome duplication and biological process this GO :0016525 and negative regulation of angiogenesis and biological process this GO :0016772 and transferase activity, this GO :0000166: nucleotide binding, this GO :0000166: nucleotide binding and also this GO :0004672: protein kinase activity and also this GO :0004674: protein serine/threonine kinase activity and also this GO :0004713: protein tyrosine kinase activity and also this GO :0005198: structural molecule activity and also this GO :0005515: protein binding and also this GO :0005524: ATP binding and also this GO :0016772: transferase activity, this GO :0004672: protein kinase activity, this GO :0004674: protein serine/threonine kinase activity, this GO :0004713: protein tyrosine kinase activity, this GO :0005198: structural molecule activity, this GO :0005515: protein binding, this GO :0005524: ATP binding, this GO :0016772: transferase activity, this GO :0017048: Rho GTPase binding, this GO :0044822: poly(A) RNA binding, this GO :0046872: metal ion binding, transferase activity, transferring phosphorus-containing groups, transferring phosphorus-containing groups and also this GO :0017048: Rho GTPase binding and also this GO :0044822: poly(A) RNA binding and also this GO :0046872: metal ion binding, transferring phosphorus-containing groups and molecular function this GO :0017048 and Rho GTPase binding and molecular function this GO :0030036 and actin cytoskeleton organization and biological process this GO :0030155 and regulation of cell adhesion and biological process this GO :0031616 and spindle pole centrosome and cellular component this GO :0032956 and regulation of actin cytoskeleton organization and biological process this GO :0035556 and intracellular signal transduction and biological process this GO :0036464 and cytoplasmic ribonucleoprotein granule and cellular component this GO :0042752 and regulation of circadian rhythm and biological process this GO :0044822 and poly(A) RNA binding and molecular function this GO :0045616 and regulation of keratinocyte differentiation and biological process this GO :0046872 and metal ion binding and molecular function this GO :0048511 and rhythmic process and biological process this GO :0051298 and centrosome duplication and biological process this GO :0051492 and regulation of stress fiber assembly and biological process this GO :0051893 and regulation of focal adhesion assembly and biological process this GO :2000114 and regulation of establishment of cell polarity and biological process this GO :2000145 and regulation of cell motility and biological process, Rho-associated |
| Identity | 10252 |
| Gene | ROCK2 |
| Long gene name | Rho associated coiled-coil containing protein kinase 2 |
| Locus | 2p25, 1 |
| Discovery year | 1999-04-23 |
| GenBank acession | D87931 |
| Entrez gene record | 9475 |
| Pubmed identfication | 9933571 |
| Classification | Pleckstrin homology domain containing |
| Havana BLAST/BLAT | OTTHUMG00000149916 |
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