| Also known as | TLR9 |
| Other names | CD_antigen: CD289, Toll-like receptor 9, toll-like receptor 9, toll-like receptor 9, toll-like receptor 9 |
| Category | Antibodies |
| Subcategory | Mnoclonal antibodies |
| Gene name | TLR9 |
| Gene name synonims | N/A |
| Other gene names | CD289, N/A, TLR9, TLR9 |
| Clonality | Monoclonal |
| Immunoglobulin isotype | IgG1, k |
| Clone | 2, 26C593 |
| Host organism | Mouse (Mus musculus) |
| Species reactivity | Due to limited knowledge and inability for testing each and every species, Gorilla, Human (Homo sapiens), Monkey (at least 90% immunogen sequence identity), Mouse (Mus musculus), Orangutan, Rat (Rattus norvegicus) <, the reactivity of the antibody may extend to other species which are not listed hereby, /b>, Chimpanzee, Gibbon, Predicted Reactivity: <, b> |
| Specificity and cross-reactivity | AAF78037), Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited, This particular antibody might cross react with speacies outside of the listed ones, KLH-conjugated synthetic peptide corresponding to amino acids 268-284 of human TLR9 isoform A (Genbank accession no |
| Purification method | Protein G Purified |
| Form/Appearance | 0, 0, 05% BSA, 05% sodium azide, PBS |
| Concentration | 5 mg/ml |
| Storage and shipping | Cycles of freezing and defrosting may denaturate the polypeptide chains of the antibodies and reduce their activity, For longer storage the antibody should be kept at -20 degrees Celsius, For short term storage keep the antibody at +4 degrees Celsius |
| Tested applications: | Flow Cytometry (FC/FACS), IHC - Frozen), Western Blot (WB), Immunohistochemistry (IHC - Paraffin |
| Properties | Depending on the epitopes used human ELISA kits can be cross reactive to many other species, Human proteins, Mainly analyzed are human serum, Modern , cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies, human cell culture supernatants and biological samples, plasma, primarily , saliva, urine, , (Homo sapiens, C, C for long term storage and for short term at + 5°, Homo sapiens sapiens), If you buy Antibodies supplied by MBS mono they should be stored frozen at - 24°, humans , ssp |
| About | Each murine monoclonal anibody has his own affinity specific for the clone, Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes, Monoclonals of this antigen are available in different clones |
| Test | A/J, BALB/c, Mouse are mature after 40 days for females and 55 days for males, SCID while the CD-1 is outbred as strain, The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year, Transgenic, congenic and inbread strains are known for C57BL/6, knock-out, Mouse , mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab, or |
| Latin name | Mus musculus |
| Gene target | 2] (IgG1, Monoclonal [ 26C593, k) TLR9 |
| Short name | 2] (IgG1, Mouse Monoclonal [clone 26C593, k) TLR9 Antibody |
| Technique | Monoclonals or monoclonal antibodies, antibodies against human proteins, antibodies for, mouses, Antibody |
| Isotype | IgG1 |
| Species | Humans, Mouses, Human |
| Alternative name | sapiens toll-like receptor 9 (Antibody to), 2] (IgG1, Mouse monoclonal [clonality 26C593, k) to H |
| Alternative technique | antibodies |
| Alternative to gene target | Extracellular, TLR9 and IDBG-407857 and ENSG00000239732 and 54106, siRNA binding, this GO :0000139 and this GO lgi membrane and cellular component this GO :0002224 and toll-like receptor signaling pathway and biological process this GO :0002237 and response to molecule of bacterial origin and biological process this GO :0002755 and MyD88-dependent toll-like receptor signaling pathway and biological process this GO :0004888 and transmembrane signaling receptor activity and molecular function this GO :0005149 and interleukin-1 receptor binding and molecular function this GO :0005515 and protein binding and molecular function this GO :0005576 and extracellular region and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0005764 and lysosome and cellular component this GO :0005768 and endosome and cellular component this GO :0005783 and endoplasmic reticulum and cellular component this GO :0005789 and endoplasmic reticulum membrane and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0006954 and inflammatory response and biological process this GO :0007165 and signal transduction and biological process this GO :0007252 and I-kappaB phosphorylation and biological process this GO :0008286 and insulin receptor signaling pathway and biological process this GO :0010008 and endosome membrane and cellular component this GO :0016021 and integral component of membrane and cellular component this GO :0016323 and basolateral plasma membrane and cellular component this GO :0016324 and apical plasma membrane and cellular component this GO :0030277 and maintenance of gastrointestinal epithelium and biological process this GO :0032009 and early pha this GO some and cellular component this GO :0032088 and negative regulation of NF-kappaB transcription factor activity and biological process this GO :0032715 and negative regulation of interleukin-6 production and biological process this GO :0032717 and negative regulation of interleukin-8 production and biological process this GO :0032722 and positive regulation of chemokine production and biological process this GO :0032728 and positive regulation of interferon-beta production and biological process this GO :0032733 and positive regulation of interleukin-10 production and biological process this GO :0032735 and positive regulation of interleukin-12 production and biological process this GO :0032741 and positive regulation of interleukin-18 production and biological process this GO :0032755 and positive regulation of interleukin-6 production and biological process this GO :0032757 and positive regulation of interleukin-8 production and biological process this GO :0032760 and positive regulation of tumor necrosis factor production and biological process this GO :0034122 and negative regulation of toll-like receptor signaling pathway and biological process this GO :0034123 and positive regulation of toll-like receptor signaling pathway and biological process this GO :0034162 and toll-like receptor 9 signaling pathway and biological process this GO :0035197 and siRNA binding and molecular function this GO :0036020 and endolysosome membrane and cellular component this GO :0042346 and positive regulation of NF-kappaB import into nucleus and biological process this GO :0042742 and defense response to bacterium and biological process this GO :0043123 and positive regulation of I-kappaB kinase/NF-kappaB signaling and biological process this GO :0043507 and positive regulation of JUN kinase activity and biological process this GO :0045078 and positive regulation of interferon-gamma biosynthetic process and biological process this GO :0045087 and innate immune response and biological process this GO :0045356 and positive regulation of interferon-alpha biosynthetic process and biological process this GO :0045359 and positive regulation of interferon-beta biosynthetic process and biological process this GO :0045944 and positive regulation of transcription from RNA polymerase II promoter and biological process this GO :0046330 and positive regulation of JNK cascade and biological process this GO :0050707 and regulation of cytokine secretion and biological process this GO :0050729 and positive regulation of inflammatory response and biological process this GO :0050829 and defense response to Gram-negative bacterium and biological process this GO :0051092 and positive regulation of NF-kappaB transcription factor activity and biological process this GO :0051770 and positive regulation of nitric-oxide synthase biosynthetic process and biological process, this GO :0004888: transmembrane signaling receptor activity, this GO :0004888: transmembrane signaling receptor activity and also this GO :0005149: interleukin-1 receptor binding and also this GO :0005515: protein binding and also this GO :0035197: siRNA binding, this GO :0005149: interleukin-1 receptor binding, this GO :0005515: protein binding, this GO :0035197: siRNA binding, toll-like receptor 9 |
| Identity | 15633 |
| Gene | TLR9 |
| Long gene name | toll like receptor 9 |
| Synonyms gene name | toll-like receptor 9 |
| Synonyms | CD289 |
| Locus | 3p21, 2 |
| Discovery year | 2001-04-27 |
| GenBank acession | AF259262 |
| Entrez gene record | 54106 |
| Pubmed identfication | 11022119 |
| Classification | CD molecules Toll like receptors |
| Havana BLAST/BLAT | OTTHUMG00000158106 |
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