| Also known as | ALPL / Alkaline Phosphatase |
| Other names | Alkaline phosphatase, Alkaline phosphatase liver/bone/kidney isozyme, alkaline phosphatase, alkaline phosphatase, alkaline phosphatase liver/bone/kidney isozyme, alkaline phosphomonoesterase, glycerophosphatase, liver/bone/kidney, liver/bone/kidney-type alkaline phosphatase, tissue-nonspecific ALP, tissue-nonspecific isozyme, tissue-nonspecific isozyme, tissue-nonspecific isozyme isoform 1, alkaline phosphatase |
| Category | Antibodies |
| Subcategory | Mnoclonal antibodies |
| Gene name | ALPL |
| Gene name synonims | N/A |
| Other gene names | ALPL, AP-TNAP, AP-TNAP, APTNAP, HOPS, TNAP, TNSALP, TNSALP, ALPL |
| Clonality | Monoclonal |
| Immunoglobulin isotype | IgG1 |
| Clone | N/A |
| Host organism | Mouse (Mus musculus) |
| Species reactivity | Due to limited knowledge and inability for testing each and every species, Human (Homo sapiens), the reactivity of the antibody may extend to other species which are not listed hereby, Bovine |
| Specificity and cross-reactivity | Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited, Species cross-reactivity: Alkaline phosphatase from human placenta and calf intestine, This particular antibody might cross react with speacies outside of the listed ones, Recognizes Alkaline Phosphatase from human bone |
| Purification method | Protein A Purified |
| Form/Appearance | 0, pH 7, 09% sodium azide, 2, PBS |
| Concentration | 1 miligram per 1 mililiter |
| Storage and shipping | Cycles of freezing/defrosting can damage the peptide chains of the antibodies thus reducing the activity, Short term storage of the antibody can be done at +4 degrees Celsius, keep the antibody at -20 degrees Celsius, For long term storage |
| Tested applications: | ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC - Paraffin) |
| Properties | Depending on the epitopes used human ELISA kits can be cross reactive to many other species, Human proteins, Mainly analyzed are human serum, Modern , cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies, human cell culture supernatants and biological samples, plasma, primarily , saliva, urine, , (Homo sapiens, C, C for long term storage and for short term at + 5°, Homo sapiens sapiens), If you buy Antibodies supplied by MBS mono they should be stored frozen at - 24°, humans , ssp |
| About | Each murine monoclonal anibody has his own affinity specific for the clone, Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes, Monoclonals of this antigen are available in different clones |
| Test | A/J, BALB/c, Mouse are mature after 40 days for females and 55 days for males, SCID while the CD-1 is outbred as strain, The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year, Transgenic, congenic and inbread strains are known for C57BL/6, knock-out, Mouse , mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab, or |
| Latin name | Mus musculus |
| Gene target | Monoclonal (IgG1) ALPL / Alkaline Phosphatase |
| Short name | Mouse Monoclonal (IgG1) ALPL / Alkaline Phosphatase Antibody |
| Technique | Monoclonals or monoclonal antibodies, antibodies against human proteins, antibodies for, mouses, Antibody |
| Isotype | IgG1 |
| Label | Alkaline Phosphatase |
| Species | Humans, Mouses, Human |
| Alternative name | liver/bone/kidney / Alkaline Phosphatase (Antibody to), sapiens alkaline phosphatase, Mouse monoclonal (IgG1) to H |
| Alternative technique | antibodies |
| Alternative to gene target | ALPL and IDBG-645614 and ENSBTAG00000008951 and 280994, ALPL and IDBG-93194 and ENSG00000162551 and 249, AP-TNAP and APTNAP and HOPS and TNAP and TNSALP, Alpl and IDBG-199139 and ENSMUSG00000028766 and 11647, Extracellular, liver/bone/kidney, metal ion binding, this GO :0001501 and skeletal system development and biological process this GO :0001649 and osteoblast differentiation and biological process this GO :0001958 and endochondral ossification and biological process this GO :0003006 and developmental process involved in reproduction and biological process this GO :0003824 and catalytic activity and molecular function this GO :0004035 and alkaline phosphatase activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005615 and extracellular space and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0008152 and metabolic process and biological process this GO :0016020 and membrane and cellular component this GO :0016021 and integral component of membrane and cellular component this GO :0016311 and dephosphorylation and biological process this GO :0016462 and pyrophosphatase activity and molecular function this GO :0016791 and phosphatase activity and molecular function this GO :0031012 and extracellular matrix and cellular component this GO :0031225 and anchored component of membrane and cellular component this GO :0032496 and response to lipopolysaccharide and biological process this GO :0033280 and response to vitamin D and biological process this GO :0046677 and response to antibiotic and biological process this GO :0046872 and metal ion binding and molecular function this GO :0051384 and response to glucocorticoid and biological process this GO :0065010 and extracellular membrane-bounded organelle and cellular component this GO :0070062 and extracellular vesicular exosome and cellular component this GO :0071407 and cellular response to organic cyclic compound and biological process this GO :0071529 and cementum mineralization and biological process, this GO :0003824: catalytic activity, this GO :0003824: catalytic activity and also this GO :0004035: alkaline phosphatase activity and also this GO :0005515: protein binding and also this GO :0016462: pyrophosphatase activity and also this GO :0016791: phosphatase activity and also this GO :0046872: metal ion binding, this GO :0004035: alkaline phosphatase activity, this GO :0005515: protein binding, this GO :0016462: pyrophosphatase activity, this GO :0016791: phosphatase activity, this GO :0046872: metal ion binding, alkaline phosphatase |
| Identity | 438 |
| Gene | ALPL |
| Long gene name | alkaline phosphatase, liver/bone/kidney |
| Synonyms gene | HOPS |
| Synonyms | TNSALP |
| Locus | 1p36, 12 |
| Discovery year | 1986-01-01 |
| GenBank acession | BC021289 |
| Entrez gene record | 249 |
| Pubmed identfication | 3532105 3446011 |
| RefSeq identity | NM_000478 |
| Classification | Alkaline phosphatases |
| Havana BLAST/BLAT | OTTHUMG00000002949 |
| Locus Specific Databases | Tissue Nonspecific Alkaline Phosphatase Gene Mutation Database |
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