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Mouse Monoclonal [clone 3F6] (IgG1) to Human BMPR2 Antibody
Mouse Monoclonal [clone 3F6] (IgG1) to Human BMPR2 Antibody size: 0.05 ml 597
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MBS MONO
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597
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0.05 ml
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| Also known as | BMPR2 |
| Other names | BMP type II receptor, BMP type II receptor, BMP type-2 receptor, BMPR-2, BMPR-II, Bone morphogenetic protein receptor type II, Bone morphogenetic protein receptor type-2, bone morphogenetic protein receptor, bone morphogenetic protein receptor type II, bone morphogenetic protein receptor type-2, type II (serine/threonine kinase), type II activin receptor-like kinase, type II receptor for bone morphogenetic protein-4, bone morphogenetic protein receptor type-2 |
| Category | Antibodies |
| Subcategory | Mnoclonal antibodies |
| Gene name | BMPR2 |
| Gene name synonims | N/A |
| Other gene names | BMP type II receptor, BMP type-2 receptor, BMPR-2, BMPR-II, BMPR-II, BMPR2, BMPR3, BMR2, BRK-3, POVD1, PPH1, PPH1, T-ALK, BMPR2 |
| Clonality | Monoclonal |
| Immunoglobulin isotype | IgG1 |
| Clone | 3F6 |
| Host organism | Mouse (Mus musculus) |
| Species reactivity | Due to limited knowledge and inability for testing each and every species, Monkey, Mouse (Mus musculus), Rat (Rattus norvegicus), the reactivity of the antibody may extend to other species which are not listed hereby, Human (Homo sapiens) |
| Specificity and cross-reactivity | Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited, This particular antibody might cross react with speacies outside of the listed ones, Human BMPR-II / BMPR2 |
| Purification method | Ascites |
| Form/Appearance | 0, 03% sodium azide, Ascites |
| Concentration | N/A |
| Storage and shipping | Cycles of freezing/defrosting can damage the peptide chains of the antibodies thus reducing the activity, Short term storage of the antibody can be done at +4 degrees Celsius, keep the antibody at -20 degrees Celsius, For long term storage |
| Tested applications: | ELISA (EIA), Immunocytochemistry (ICC), Immunofluorescence (IF), Western Blot (WB), Immunohistochemistry (IHC) |
| Properties | Depending on the epitopes used human ELISA kits can be cross reactive to many other species, Human proteins, Mainly analyzed are human serum, Modern , cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies, human cell culture supernatants and biological samples, plasma, primarily , saliva, urine, , (Homo sapiens, C, C for long term storage and for short term at + 5°, Homo sapiens sapiens), If you buy Antibodies supplied by MBS mono they should be stored frozen at - 24°, humans , ssp |
| About | Each murine monoclonal anibody has his own affinity specific for the clone, Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes, Monoclonals of this antigen are available in different clones |
| Test | A/J, BALB/c, Mouse are mature after 40 days for females and 55 days for males, SCID while the CD-1 is outbred as strain, The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year, Transgenic, congenic and inbread strains are known for C57BL/6, knock-out, Mouse , mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab, or |
| Latin name | Mus musculus |
| Gene target | Monoclonal [ 3F6] (IgG1) BMPR2 |
| Short name | Mouse Monoclonal [clone 3F6] (IgG1) BMPR2 Antibody |
| Technique | Monoclonals or monoclonal antibodies, antibodies against human proteins, antibodies for, mouses, Antibody |
| Isotype | IgG1 |
| Species | Humans, Mouses, Human |
| Alternative name | classification II (serine/threonine kinase) (Antibody to), sapiens bone morphogenetic protein receptor, Mouse monoclonal [clonality 3F6] (IgG1) to H |
| Alternative technique | antibodies |
| Alternative to gene target | BMPR-II and BMPR3 and BMR2 and BRK-3 and POVD1 and PPH1 and T-ALK, BMPR2 and IDBG-78880 and ENSG00000204217 and 659, BT, Bmpr2 and IDBG-158574 and ENSMUSG00000067336 and 12168, Extracellular, activin receptor activity, this GO :0001707 and mesoderm formation and biological process this GO :0001938 and positive regulation of endothelial cell proliferation and biological process this GO :0001946 and lymphangiogenesis and biological process this GO :0001974 and blood vessel remodeling and biological process this GO :0002063 and chondrocyte development and biological process this GO :0003085 and negative regulation of systemic arterial blood pressure and biological process this GO :0004672 and protein kinase activity and molecular function this GO :0004675 and transmembrane receptor protein serine/threonine kinase activity and molecular function this GO :0004702 and receptor signaling protein serine/threonine kinase activity and molecular function this GO :0004713 and protein tyrosine kinase activity and molecular function this GO :0005024 and transforming growth factor beta-activated receptor activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005524 and ATP binding and molecular function this GO :0005615 and extracellular space and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0005887 and integral component of plasma membrane and cellular component this GO :0005901 and caveola and cellular component this GO :0006366 and transcription from RNA polymerase II promoter and biological process this GO :0006468 and protein phosphorylation and biological process this GO :0007178 and transmembrane receptor protein serine/threonine kinase signaling pathway and biological process this GO :0007420 and brain development and biological process this GO :0009267 and cellular response to starvation and biological process this GO :0009925 and basal plasma membrane and cellular component this GO :0009952 and anterior/posterior pattern specification and biological process this GO :0009986 and cell surface and cellular component this GO :0010595 and positive regulation of endothelial cell migration and biological process this GO :0010634 and positive regulation of epithelial cell migration and biological process this GO :0010862 and positive regulation of pathway-restricted SMAD protein phosphorylation and biological process this GO :0014916 and regulation of lung blood pressure and biological process this GO :0016020 and membrane and cellular component this GO :0016324 and apical plasma membrane and cellular component this GO :0016362 and activin receptor activity, this GO :0004672: protein kinase activity, this GO :0004672: protein kinase activity and also this GO :0004675: transmembrane receptor protein serine/threonine kinase activity and also this GO :0004702: receptor signaling protein serine/threonine kinase activity and also this GO :0004713: protein tyrosine kinase activity and also this GO :0005024: transforming growth factor beta-activated receptor activity and also this GO :0005515: protein binding and also this GO :0005524: ATP binding and also this GO :0016362: activin receptor activity, this GO :0004675: transmembrane receptor protein serine/threonine kinase activity, this GO :0004702: receptor signaling protein serine/threonine kinase activity, this GO :0004713: protein tyrosine kinase activity, this GO :0005024: transforming growth factor beta-activated receptor activity, this GO :0005515: protein binding, this GO :0005524: ATP binding, this GO :0016362: activin receptor activity, this GO :0016772: transferase activity, this GO :0019838: growth factor binding, this GO :0046872: metal ion binding, transferring phosphorus-containing groups, transferring phosphorus-containing groups and also this GO :0019838: growth factor binding and also this GO :0046872: metal ion binding, transferring phosphorus-containing groups and molecular function this GO :0019838 and growth factor binding and molecular function this GO :0023014 and signal transduction by phosphorylation and biological process this GO :0030308 and negative regulation of cell growth and biological process this GO :0030425 and dendrite and cellular component this GO :0030501 and positive regulation of bone mineralization and biological process this GO :0030509 and BMP signaling pathway and biological process this GO :0030513 and positive regulation of BMP signaling pathway and biological process this GO :0032924 and activin receptor signaling pathway and biological process this GO :0042127 and regulation of cell proliferation and biological process this GO :0043025 and neuronal cell body and cellular component this GO :0044214 and fully spanning plasma membrane and cellular component this GO :0045669 and positive regulation of osteoblast differentiation and biological process this GO :0045906 and negative regulation of vasoconstriction and biological process this GO :0046872 and metal ion binding and molecular function this GO :0048010 and vascular endothelial growth factor receptor signaling pathway and biological process this GO :0048286 and lung alveolus development and biological process this GO :0048842 and positive regulation of axon extension involved in axon guidance and biological process this GO :0060041 and retina development in camera-type eye and biological process this GO :0060173 and limb development and biological process this GO :0060836 and lymphatic endothelial cell differentiation and biological process this GO :0060840 and artery development and biological process this GO :0060841 and venous blood vessel development and biological process this GO :0061298 and retina vasculature development in camera-type eye and biological process this GO :1902731 and negative regulation of chondrocyte proliferation and biological process this GO :2000279 and negative regulation of DNA biosynthetic process and biological process, type II, type II (serine/threonine kinase), type II and also this GO :0016772: transferase activity, type II and molecular function this GO :0016772 and transferase activity, 25715 and IDBG-643309 and ENSBTAG00000006420 and 407127, bone morphogenetic protein receptor |
| Identity | 1078 |
| Gene | BMPR2 |
| Long gene name | bone morphogenetic protein receptor type 2 |
| Synonyms gene | PPH1 |
| Synonyms gene name | primary pulmonary hypertension 1 bone morphogenetic protein receptor, type II (serine/threonine kinase) bone morphogenetic protein receptor type II |
| Synonyms | BRK-3 T-ALK BMPR3 BMPR-II |
| Locus | 2q33, 1-q33, 2 |
| Discovery year | 1997-03-19 |
| GenBank acession | Z48923 |
| Entrez gene record | 659 |
| Pubmed identfication | 7791754 |
| RefSeq identity | NM_001204 |
| Classification | Type 2 receptor serine/threonine kinases |
| Havana BLAST/BLAT | OTTHUMG00000133617 |
| Locus Specific Databases | LRG_712 |