| Also known as | CASP9 / Caspase 9 |
| Other names | APAF-3, Apoptotic protease Mch-6, Apoptotic protease-activating factor 3, Caspase-9, ICE-LAP6, ICE-like apoptotic protease 6, ICE-like apoptotic protease 6, apoptosis-related cysteine peptidase, apoptotic protease MCH-6, apoptotic protease activating factor 3, caspase 9, caspase-9, protein phosphatase 1, regulatory subunit 56, caspase-9 isoform alpha |
| Category | Antibodies |
| Subcategory | Mnoclonal antibodies |
| Gene name | CASP9 |
| Gene name synonims | N/A |
| Other gene names | APAF-3, APAF-3, APAF3, CASP-9, CASP9, ICE-LAP6, ICE-LAP6, MCH6, MCH6, PPP1R56, CASP9 |
| Clonality | Monoclonal |
| Immunoglobulin isotype | IgG1 |
| Clone | 42057 |
| Host organism | Mouse (Mus musculus) |
| Species reactivity | Due to limited knowledge and inability for testing each and every species, Monkey, the reactivity of the antibody may extend to other species which are not listed hereby, Human (Homo sapiens) |
| Specificity and cross-reactivity | Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited, This antibody recognizes the pro-caspase-9 human recombinant protein as well as pro-caspase -9 from human and monkey cell lysates, This particular antibody might cross react with speacies outside of the listed ones, corresponding to the apparent molecular mass of the caspase-9 on SDS-PAGE immunoblots, in samples from human and monkey origins, Detects an ~46-50 kD protein |
| Purification method | Protein G Purified |
| Form/Appearance | 0, 50% glycerol, 01 mM PMSF, PBS |
| Concentration | 1 miligram per 1 mililiter |
| Storage and shipping | For long term storage aliquot and keep the antibody at -20 degrees Celsius, Freeze-thaw cycles should be avoided in order to retain the activity of the antibody, Store at +4 degrees Celsius for short term storage |
| Tested applications: | Immunoprecipitation (IP), Western Blot (WB), Immunohistochemistry (IHC - Paraffin) |
| Properties | Depending on the epitopes used human ELISA kits can be cross reactive to many other species, Human proteins, Mainly analyzed are human serum, Modern , cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies, human cell culture supernatants and biological samples, plasma, primarily , saliva, urine, , (Homo sapiens, C, C for long term storage and for short term at + 5°, Homo sapiens sapiens), If you buy Antibodies supplied by MBS mono they should be stored frozen at - 24°, humans , ssp |
| Gene | CASP9 |
| About | Each murine monoclonal anibody has his own affinity specific for the clone, Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes, Monoclonals of this antigen are available in different clones |
| Test | A/J, BALB/c, Mouse are mature after 40 days for females and 55 days for males, SCID while the CD-1 is outbred as strain, The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year, Transgenic, congenic and inbread strains are known for C57BL/6, knock-out, Mouse , mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab, or |
| Latin name | Mus musculus |
| Gene target | Monoclonal [ 2-22] (IgG1) CASP9 / Caspase 9 |
| Short name | Mouse Monoclonal [clone 2-22] (IgG1) CASP9 / Caspase 9 Antibody |
| Technique | Monoclonals or monoclonal antibodies, antibodies against human proteins, antibodies for, mouses, Antibody |
| Isotype | IgG1 |
| Species | Humans, Mouses, Human |
| Alternative name | apoptosis-related cysteine peptidase / caspase 9 (Antibody to), sapiens caspase 9, Mouse monoclonal [clonality 2-22] (IgG1) to H |
| Alternative technique | antibodies |
| Alternative to gene target | APAF-3 and APAF3 and ICE-LAP6 and MCH6 and PPP1R56, CASP9 and IDBG-635833 and ENSBTAG00000002472 and 100140945, CASP9 and IDBG-90895 and ENSG00000132906 and 842, Casp9 and IDBG-202405 and ENSMUSG00000028914 and 12371, apoptosis-related cysteine peptidase, nuclei, protein kinase binding, this GO :0004197 and cysteine-type endopeptidase activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005622 and intracellular and cellular component this GO :0005634 and nucleus and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0005739 and mitochondrion and cellular component this GO :0005829 and cytosol and cellular component this GO :0006508 and proteolysis and biological process this GO :0006915 and apoptotic process and biological process this GO :0006919 and activation of cysteine-type endopeptidase activity involved in apoptotic process and biological process this GO :0006974 and cellular response to DNA damage stimulus and biological process this GO :0007173 and epidermal growth factor receptor signaling pathway and biological process this GO :0007568 and aging and biological process this GO :0008047 and enzyme activator activity and molecular function this GO :0008233 and peptidase activity and molecular function this GO :0008234 and cysteine-type peptidase activity and molecular function this GO :0008543 and fibroblast growth factor receptor signaling pathway and biological process this GO :0008630 and intrinsic apoptotic signaling pathway in response to DNA damage and biological process this GO :0008635 and activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c and biological process this GO :0009411 and response to UV and biological process this GO :0014070 and response to organic cyclic compound and biological process this GO :0017124 and SH3 domain binding and molecular function this GO :0019901 and protein kinase binding and molecular function this GO :0030220 and platelet formation and biological process this GO :0032025 and response to cobalt ion and biological process this GO :0032355 and response to estradiol and biological process this GO :0032496 and response to lipopolysaccharide and biological process this GO :0034349 and glial cell apoptotic process and biological process this GO :0034644 and cellular response to UV and biological process this GO :0038095 and Fc-epsilon receptor signaling pathway and biological process this GO :0042770 and signal transduction in response to DNA damage and biological process this GO :0042981 and regulation of apoptotic process and biological process this GO :0043065 and positive regulation of apoptotic process and biological process this GO :0043293 and apoptosome and cellular component this GO :0043525 and positive regulation of neuron apoptotic process and biological process this GO :0045087 and innate immune response and biological process this GO :0046677 and response to antibiotic and biological process this GO :0048011 and neurotrophin TRK receptor signaling pathway and biological process this GO :0048015 and phosphatidylinositol-mediated signaling and biological process this GO :0071407 and cellular response to organic cyclic compound and biological process this GO :0071549 and cellular response to dexamethasone stimulus and biological process this GO :0097193 and intrinsic apoptotic signaling pathway and biological process this GO :2001020 and regulation of response to DNA damage stimulus and biological process, this GO :0004197: cysteine-type endopeptidase activity, this GO :0004197: cysteine-type endopeptidase activity and also this GO :0005515: protein binding and also this GO :0008047: enzyme activator activity and also this GO :0008233: peptidase activity and also this GO :0008234: cysteine-type peptidase activity and also this GO :0017124: SH3 domain binding and also this GO :0019901: protein kinase binding, this GO :0005515: protein binding, this GO :0008047: enzyme activator activity, this GO :0008233: peptidase activity, this GO :0008234: cysteine-type peptidase activity, this GO :0017124: SH3 domain binding, this GO :0019901: protein kinase binding, caspase 9 |
| Identity | 1511 |
| Long gene name | caspase 9 |
| Synonyms gene name | apoptosis-related cysteine peptidase , apoptosis-related cysteine protease caspase 9, caspase 9 |
| Synonyms | MCH6 ICE-LAP6 APAF-3 PPP1R56 |
| Synonyms name | protein phosphatase 1, regulatory subunit 56 |
| Locus | 1p36, 21 |
| Discovery year | 1996-11-11 |
| GenBank acession | U60521 |
| Entrez gene record | 842 |
| Pubmed identfication | 8663294 9390557 |
| RefSeq identity | NM_032996 |
| Classification | Caspase recruitment domain containing Protein phosphatase 1 regulatory subunits Caspases Apoptosome |
| Havana BLAST/BLAT | OTTHUMG00000002256 |
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