Name : Mouse Monoclonal [clone 056B-214.2.4.2] (IgG1) to Human Complement C6 Antibody
Supplier : MBS MONO
Price :597
SKU : GEN6036563088
| Also known as | Complement C6 |
| Other names | Complement component C6, N/A, complement component 6, complement component C6, complement component C6 |
| Category | Antibodies |
| Subcategory | Mnoclonal antibodies |
| Gene name | C6 |
| Gene name synonims | N/A |
| Other gene names | C6, N/A, N/A, C6 |
| Clonality | Monoclonal |
| Immunoglobulin isotype | IgG1 |
| Clone | 056B-214, 2, 2, 4 |
| Host organism | Mouse (Mus musculus) |
| Species reactivity | Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby, Human (Homo sapiens) |
| Specificity and cross-reactivity | C5b-7 then functions as a receptor for components C8 and C9 which form the complement membrane attack complex (MAC), Deficiency of C6 results in susceptibility to bacterial infection, Recognizes MAC, Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited, The factor I modules of C6 bind the C terminus of the C5b alpha-chain, This enables the formation of the C5b-7 precursor complex, This particular antibody might cross react with speacies outside of the listed ones, anchoring the molecule to the membrane and also binds complement component 7, Recognizes complement component 6 (C6) a 104 kD member of the complement C6/C7/C8/C9 family present in blood serum |
| Purification method | Protein A Purified |
| Form/Appearance | 0, Sourced in Ascites, 09% sodium azide, Borate buffered saline |
| Concentration | 1 miligram per 1 mililiter |
| Storage and shipping | Cycles of freeze/thaw may reduce the activity, For longer periods of time, Store the antibodies in an undiluted form, freeze the antibody and keep it at -20 degrees Celsius, Keep the antibody refrigerated at +4 degrees Celsius for short periods of time |
| Tested applications: | ELISA (EIA), Flow Cytometry (FC/FACS), Immunohistochemistry (IHC - Paraffin) |
| Properties | Depending on the epitopes used human ELISA kits can be cross reactive to many other species, Human proteins, Mainly analyzed are human serum, Modern , cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies, human cell culture supernatants and biological samples, plasma, primarily , saliva, urine,  , (Homo sapiens, C, C for long term storage and for short term at + 5°, Homo sapiens sapiens), If you buy Antibodies supplied by MBS mono they should be stored frozen at - 24°, humans , ssp |
| About | Each murine monoclonal anibody has his own affinity specific for the clone, Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes, Monoclonals of this antigen are available in different clones |
| Test | A/J, BALB/c, Mouse are mature after 40 days for females and 55 days for males, SCID while the CD-1 is outbred as strain, The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year, Transgenic, congenic and inbread strains are known for C57BL/6, knock-out, Mouse , mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab, or  |
| Latin name | Mus musculus |
| Gene target | 2, 2] (IgG1) Complement C6, 4, Monoclonal [ 056B-214 |
| Short name | 2, 2] (IgG1) Complement C6 Antibody, 4, Mouse Monoclonal [clone 056B-214 |
| Technique | Monoclonals or monoclonal antibodies, antibodies against human proteins, antibodies for, mouses, Antibody |
| Isotype | IgG1 |
| Species | Humans, Mouses, Human |
| Alternative name | sapiens Complement complement component 6 (Antibody to), 2, 2] (IgG1) to H, 4, Mouse monoclonal [clonality 056B-214 |
| Alternative technique | antibodies |
| Alternative to gene target | C6 and IDBG-127938 and ENSMUSG00000022181 and 12274, C6 and IDBG-18604 and ENSG00000039537 and 729, C6 and IDBG-629747 and ENSBTAG00000014177 and 507749, Extracellular, classical pathway and biological process this GO :0019835 and cytolysis and biological process this GO :0030449 and regulation of complement activation and biological process this GO :0045087 and innate immune response and biological process, protein binding, this GO :0001701 and in utero embryonic development and biological process this GO :0005515 and protein binding and molecular function this GO :0005576 and extracellular region and cellular component this GO :0005579 and membrane attack complex and cellular component this GO :0006956 and complement activation and biological process this GO :0006958 and complement activation, this GO :0005515: protein binding, this GO :0005515: protein binding, complement component 6 |