| Also known as | EP300 / p300 |
| Other names | 300kD, E1A binding protein p300, E1A-associated protein p300, E1A-associated protein p300, E1A-binding protein, Histone acetyltransferase p300, histone acetyltransferase p300, p300 HAT, histone acetyltransferase p300 |
| Category | Antibodies |
| Subcategory | Mnoclonal antibodies |
| Gene name | EP300 |
| Gene name synonims | p300 |
| Other gene names | EP300, KAT3B, P300, RSTS2, p300, p300 HAT, EP300 |
| Clonality | Monoclonal |
| Immunoglobulin isotype | IgG1 |
| Clone | 1D2 |
| Host organism | Mouse (Mus musculus) |
| Species reactivity | Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby, Human (Homo sapiens) |
| Specificity and cross-reactivity | Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited, This particular antibody might cross react with speacies outside of the listed ones, Human p300 |
| Purification method | Protein A Purified |
| Form/Appearance | Sourced in Ascites, pH 7, 2, PBS |
| Concentration | 2 mg/ml |
| Storage and shipping | Cycles of freezing and thawing may destroy the polypeptide chains of the antibodies and should be avoided, For extended periods of time, storage at -80 degrees Celsius is recommended, After aliquoting the antibody should be stored at -20 degrees Celsius |
| Tested applications: | ELISA (EIA), Immunofluorescence (IF), Western Blot (WB), Immunohistochemistry (IHC - Paraffin) |
| Properties | Depending on the epitopes used human ELISA kits can be cross reactive to many other species, Human proteins, Mainly analyzed are human serum, Modern , cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies, human cell culture supernatants and biological samples, plasma, primarily , saliva, urine, , (Homo sapiens, C, C for long term storage and for short term at + 5°, Homo sapiens sapiens), If you buy Antibodies supplied by MBS mono they should be stored frozen at - 24°, humans , ssp |
| About | Each murine monoclonal anibody has his own affinity specific for the clone, Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes, Monoclonals of this antigen are available in different clones |
| Test | A/J, BALB/c, Mouse are mature after 40 days for females and 55 days for males, SCID while the CD-1 is outbred as strain, The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year, Transgenic, congenic and inbread strains are known for C57BL/6, knock-out, Mouse , mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab, or |
| Latin name | Mus musculus |
| Gene target | Monoclonal [ 1D2] (IgG1) EP300 / p300 |
| Short name | Mouse Monoclonal [clone 1D2] (IgG1) EP300 / p300 Antibody |
| Technique | Monoclonals or monoclonal antibodies, antibodies against human proteins, antibodies for, mouses, Antibody |
| Isotype | IgG1 |
| Species | Humans, Mouses, Human |
| Alternative name | sapiens E1A binding protein p300 / p300 (Antibody to), Mouse monoclonal [clonality 1D2] (IgG1) to H |
| Alternative technique | antibodies |
| Alternative to gene target | DNA-templated and biological process this GO :0006355 and regulation of transcription, DNA-templated and biological process this GO :0006475 and internal protein amino acid acetylation and biological process this GO :0006915 and apoptotic process and biological process this GO :0007219 and Notch signaling pathway and biological process this GO :0007399 and nervous system development and biological process this GO :0007507 and heart development and biological process this GO :0007519 and skeletal muscle tissue development and biological process this GO :0007623 and circadian rhythm and biological process this GO :0008013 and beta-catenin binding and molecular function this GO :0008134 and transcription factor binding and molecular function this GO :0008270 and zinc ion binding and molecular function this GO :0009749 and response to glucose and biological process this GO :0009887 and organ morphogenesis and biological process this GO :0010560 and positive regulation of glycoprotein biosynthetic process and biological process this GO :0010628 and positive regulation of gene expression and biological process this GO :0010942 and positive regulation of cell death and biological process this GO :0014070 and response to organic cyclic compound and biological process this GO :0014737 and positive regulation of muscle atrophy and biological process this GO :0016032 and viral process and biological process this GO :0016407 and acetyltransferase activity and molecular function this GO :0016573 and histone acetylation and biological process this GO :0016746 and transferase activity, DNA-templated and biological process this GO :0045944 and positive regulation of transcription from RNA polymerase II promoter and biological process this GO :0046332 and SMAD binding and molecular function this GO :0048565 and digestive tract development and biological process this GO :0050681 and androgen receptor binding and molecular function this GO :0050714 and positive regulation of protein secretion and biological process this GO :0051019 and mitogen-activated protein kinase binding and molecular function this GO :0051059 and NF-kappaB binding and molecular function this GO :0051091 and positive regulation of sequence-specific DNA binding transcription factor activity and biological process this GO :0051592 and response to calcium ion and biological process this GO :0051726 and regulation of cell cycle and biological process this GO :0060177 and regulation of angiotensin metabolic process and biological process this GO :0060298 and positive regulation of sarcomere organization and biological process this GO :0060548 and negative regulation of cell death and biological process this GO :0060765 and regulation of androgen receptor signaling pathway and biological process this GO :0061418 and regulation of transcription from RNA polymerase II promoter in response to hypoxia and biological process this GO :0065004 and protein-DNA complex assembly and biological process this GO :0070301 and cellular response to hydrogen peroxide and biological process this GO :0070542 and response to fatty acid and biological process this GO :0071236 and cellular response to antibiotic and biological process this GO :0071300 and cellular response to retinoic acid and biological process this GO :0071320 and cellular response to cAMP and biological process this GO :0071333 and cellular response to glucose stimulus and biological process this GO :0071389 and cellular response to mineralocorticoid stimulus and biological process this GO :0071407 and cellular response to organic cyclic compound and biological process this GO :0071456 and cellular response to hypoxia and biological process this GO :0071548 and response to dexamethasone and biological process this GO :0071549 and cellular response to dexamethasone stimulus and biological process this GO :0090043 and regulation of tubulin deacetylation and biological process this GO :0097157 and pre-mRNA intronic binding and molecular function this GO :1901985 and positive regulation of protein acetylation and biological process this GO :1990090 and cellular response to nerve growth factor stimulus and biological process this GO :2000629 and negative regulation of miRNA metabolic process and biological process, EP300 and IDBG-641857 and ENSBTAG00000016198 and, EP300 and IDBG-8992 and ENSG00000100393 and 2033, Ep300 and IDBG-164782 and ENSMUSG00000055024 and 328572, KAT3B and p300 and RSTS2, nuclei, this GO :0000086 and G2/M transition of mitotic cell cycle and biological process this GO :0000122 and negative regulation of transcription from RNA polymerase II promoter and biological process this GO :0000123 and histone acetyltransferase complex and cellular component this GO :0000278 and mitotic cell cycle and biological process this GO :0000785 and chromatin and cellular component this GO :0000978 and RNA polymerase II core promoter proximal region sequence-specific DNA binding and molecular function this GO :0000979 and RNA polymerase II core promoter sequence-specific DNA binding and molecular function this GO :0001047 and core promoter binding and molecular function this GO :0001085 and RNA polymerase II transcription factor binding and molecular function this GO :0001102 and RNA polymerase II activating transcription factor binding and molecular function this GO :0001159 and core promoter proximal region DNA binding and molecular function this GO :0001666 and response to hypoxia and biological process this GO :0001756 and somitogenesis and biological process this GO :0001889 and liver development and biological process this GO :0001934 and positive regulation of protein phosphorylation and biological process this GO :0002039 and p53 binding and molecular function this GO :0003677 and DNA binding and molecular function this GO :0003682 and chromatin binding and molecular function this GO :0003700 and sequence-specific DNA binding transcription factor activity and molecular function this GO :0003712 and transcription cofactor activity and molecular function this GO :0003713 and transcription coactivator activity and molecular function this GO :0003823 and antigen binding and molecular function this GO :0004402 and histone acetyltransferase activity and molecular function this GO :0004468 and lysine N-acetyltransferase activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0005654 and nucleoplasm and cellular component this GO :0005667 and transcription factor complex and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0006325 and chromatin organization and biological process this GO :0006351 and transcription, this GO :0000978: RNA polymerase II core promoter proximal region sequence-specific DNA binding, this GO :0000978: RNA polymerase II core promoter proximal region sequence-specific DNA binding and also this GO :0000979: RNA polymerase II core promoter sequence-specific DNA binding and also this GO :0001047: core promoter binding and also this GO :0001085: RNA polymerase II transcription factor binding and also this GO :0001102: RNA polymerase II activating transcription factor binding and also this GO :0001159: core promoter proximal region DNA binding and also this GO :0002039: p53 binding and also this GO :0003677: DNA binding and also this GO :0003682: chromatin binding and also this GO :0003700: sequence-specific DNA binding transcription factor activity and also this GO :0003712: transcription cofactor activity and also this GO :0003713: transcription coactivator activity and also this GO :0003823: antigen binding and also this GO :0004402: histone acetyltransferase activity and also this GO :0004468: lysine N-acetyltransferase activity and also this GO :0005515: protein binding and also this GO :0008013: beta-catenin binding and also this GO :0008134: transcription factor binding and also this GO :0008270: zinc ion binding and also this GO :0016407: acetyltransferase activity and also this GO :0016746: transferase activity, this GO :0000979: RNA polymerase II core promoter sequence-specific DNA binding, this GO :0001047: core promoter binding, this GO :0001085: RNA polymerase II transcription factor binding, this GO :0001102: RNA polymerase II activating transcription factor binding, this GO :0001159: core promoter proximal region DNA binding, this GO :0002039: p53 binding, this GO :0003677: DNA binding, this GO :0003682: chromatin binding, this GO :0003700: sequence-specific DNA binding transcription factor activity, this GO :0003712: transcription cofactor activity, this GO :0003713: transcription coactivator activity, this GO :0003823: antigen binding, this GO :0004402: histone acetyltransferase activity, this GO :0004468: lysine N-acetyltransferase activity, this GO :0005515: protein binding, this GO :0008013: beta-catenin binding, this GO :0008134: transcription factor binding, this GO :0008270: zinc ion binding, this GO :0016407: acetyltransferase activity, this GO :0016746: transferase activity, this GO :0019901: protein kinase binding, this GO :0031490: chromatin DNA binding, this GO :0032403: protein complex binding, this GO :0033613: activating transcription factor binding, this GO :0035257: nuclear hormone receptor binding, this GO :0035259: glucocorticoid receptor binding, this GO :0042975: peroxisome proliferator activated receptor binding, this GO :0043425: bHLH transcription factor binding, this GO :0046332: SMAD binding, this GO :0050681: androgen receptor binding, this GO :0051019: mitogen-activated protein kinase binding, this GO :0051059: NF-kappaB binding, this GO :0097157: pre-mRNA intronic binding, transferase activity, transferring acyl groups, transferring acyl groups and also this GO :0019901: protein kinase binding and also this GO :0031490: chromatin DNA binding and also this GO :0032403: protein complex binding and also this GO :0033613: activating transcription factor binding and also this GO :0035257: nuclear hormone receptor binding and also this GO :0035259: glucocorticoid receptor binding and also this GO :0042975: peroxisome proliferator activated receptor binding and also this GO :0043425: bHLH transcription factor binding and also this GO :0046332: SMAD binding and also this GO :0050681: androgen receptor binding and also this GO :0051019: mitogen-activated protein kinase binding and also this GO :0051059: NF-kappaB binding and also this GO :0097157: pre-mRNA intronic binding, transferring acyl groups and molecular function this GO :0018076 and N-terminal peptidyl-lysine acetylation and biological process this GO :0018393 and internal peptidyl-lysine acetylation and biological process this GO :0019901 and protein kinase binding and molecular function this GO :0030307 and positive regulation of cell growth and biological process this GO :0030324 and lung development and biological process this GO :0031324 and negative regulation of cellular metabolic process and biological process this GO :0031325 and positive regulation of cellular metabolic process and biological process this GO :0031490 and chromatin DNA binding and molecular function this GO :0032025 and response to cobalt ion and biological process this GO :0032092 and positive regulation of protein binding and biological process this GO :0032403 and protein complex binding and molecular function this GO :0032481 and positive regulation of type I interferon production and biological process this GO :0032526 and response to retinoic acid and biological process this GO :0032967 and positive regulation of collagen biosynthetic process and biological process this GO :0032993 and protein-DNA complex and cellular component this GO :0033160 and positive regulation of protein import into nucleus, translocation and biological process this GO :0033613 and activating transcription factor binding and molecular function this GO :0034612 and response to tumor necrosis factor and biological process this GO :0035257 and nuclear hormone receptor binding and molecular function this GO :0035259 and glucocorticoid receptor binding and molecular function this GO :0035690 and cellular response to drug and biological process this GO :0035984 and cellular response to trichostatin A and biological process this GO :0042493 and response to drug and biological process this GO :0042542 and response to hydrogen peroxide and biological process this GO :0042771 and intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator and biological process this GO :0042975 and peroxisome proliferator activated receptor binding and molecular function this GO :0043154 and negative regulation of cysteine-type endopeptidase activity involved in apoptotic process and biological process this GO :0043388 and positive regulation of DNA binding and biological process this GO :0043425 and bHLH transcription factor binding and molecular function this GO :0043491 and protein kinase B signaling and biological process this GO :0043627 and response to estrogen and biological process this GO :0043923 and positive regulation by host of viral transcription and biological process this GO :0043966 and histone H3 acetylation and biological process this GO :0043967 and histone H4 acetylation and biological process this GO :0043969 and histone H2B acetylation and biological process this GO :0045087 and innate immune response and biological process this GO :0045471 and response to ethanol and biological process this GO :0045727 and positive regulation of translation and biological process this GO :0045773 and positive regulation of axon extension and biological process this GO :0045793 and positive regulation of cell size and biological process this GO :0045862 and positive regulation of proteolysis and biological process this GO :0045893 and positive regulation of transcription, E1A binding protein p300 |
| Identity | 3373 |
| Gene | EP300 |
| Long gene name | E1A binding protein p300 |
| Synonyms | p300 KAT3B |
| Synonyms name | histone acetyltransferase p300 |
| Locus | 22q13, 2 |
| Discovery year | 1998-07-31 |
| GenBank acession | U01877 |
| Entrez gene record | 2033 |
| Pubmed identfication | 7523245 |
| RefSeq identity | NM_001429 |
| Classification | Zinc fingers ZZ-type Lysine acetyltransferases |
| Havana BLAST/BLAT | OTTHUMG00000150937 |
| Locus Specific Databases | LOVD - Leiden Open Variation Database |
Technique
Supplier
Species
Label
Iso Type
Host
Tissue