| Also known as | HDAC1 |
| Other names | Histone deacetylase 1, N/A, histone deacetylase 1, histone deacetylase 1, reduced potassium dependency, yeast homolog-like 1, histone deacetylase 1 |
| Category | Antibodies |
| Subcategory | Mnoclonal antibodies |
| Gene name | HDAC1 |
| Gene name synonims | N/A |
| Other gene names | GON-10, HD1, HD1, HDAC1, RPD3, RPD3L1, RPD3L1, HDAC1 |
| Clonality | Monoclonal |
| Immunoglobulin isotype | IgG1 |
| Clone | N/A |
| Host organism | Mouse (Mus musculus) |
| Species reactivity | Bovine, Due to limited knowledge and inability for testing each and every species, Gorilla, Hamster, Horse, Human (Homo sapiens), Monkey, Mouse (Mus musculus), Orangutan, Pig (at least 90% immunogen sequence identity), Rabbit (Oryctolagus cuniculus) <, the reactivity of the antibody may extend to other species which are not listed hereby, /b>, Gibbon, Predicted Reactivity: <, Rat (Rattus norvegicus), b> |
| Specificity and cross-reactivity | Mr 60kD, Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited, Species cross-reactivity: mouse, This particular antibody might cross react with speacies outside of the listed ones, Recognizes human HDAC1 |
| Purification method | Protein G Purified |
| Form/Appearance | 0, 02% sodium azide, PBS |
| Concentration | 25 mg/ml |
| Storage and shipping | Cycles of freezing/defrosting can damage the peptide chains of the antibodies thus reducing the activity, Short term storage of the antibody can be done at +4 degrees Celsius, keep the antibody at -20 degrees Celsius, For long term storage |
| Tested applications: | Immunocytochemistry (ICC), Immunoprecipitation (IP), Western Blot (WB), Immunohistochemistry (IHC - Paraffin) |
| Properties | Depending on the epitopes used human ELISA kits can be cross reactive to many other species, Human proteins, Mainly analyzed are human serum, Modern , cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies, human cell culture supernatants and biological samples, plasma, primarily , saliva, urine, , (Homo sapiens, C, C for long term storage and for short term at + 5°, Homo sapiens sapiens), If you buy Antibodies supplied by MBS mono they should be stored frozen at - 24°, humans , ssp |
| About | Each murine monoclonal anibody has his own affinity specific for the clone, Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes, Monoclonals of this antigen are available in different clones |
| Test | A/J, BALB/c, Mouse are mature after 40 days for females and 55 days for males, SCID while the CD-1 is outbred as strain, The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year, Transgenic, congenic and inbread strains are known for C57BL/6, knock-out, Mouse , mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab, or |
| Latin name | Mus musculus |
| Gene target | Monoclonal (IgG1) HDAC1 |
| Short name | Mouse Monoclonal (IgG1) HDAC1 Antibody |
| Technique | Monoclonals or monoclonal antibodies, antibodies against human proteins, antibodies for, mouses, Antibody |
| Isotype | IgG1 |
| Species | Humans, Mouses, Human |
| Alternative name | sapiens histone deacetylase 1 (Antibody to), Mouse monoclonal (IgG1) to H |
| Alternative technique | antibodies |
| Alternative to gene target | DNA-templated and biological process this GO :0006367 and transcription initiation from RNA polymerase II promoter and biological process this GO :0006476 and protein deacetylation and biological process this GO :0007179 and transforming growth factor beta receptor signaling pathway and biological process this GO :0007219 and Notch signaling pathway and biological process this GO :0007596 and blood coagulation and biological process this GO :0008134 and transcription factor binding and molecular function this GO :0008284 and positive regulation of cell proliferation and biological process this GO :0009913 and epidermal cell differentiation and biological process this GO :0010467 and gene expression and biological process this GO :0010870 and positive regulation of receptor biosynthetic process and biological process this GO :0016032 and viral process and biological process this GO :0016568 and chromatin modification and biological process this GO :0016575 and histone deacetylation and biological process this GO :0016580 and Sin3 complex and cellular component this GO :0016581 and NuRD complex and cellular component this GO :0019213 and deacetylase activity and molecular function this GO :0019899 and enzyme binding and molecular function this GO :0031492 and nucleosomal DNA binding and molecular function this GO :0032041 and NAD-dependent histone deacetylase activity (H3-K14 specific) and molecular function this GO :0032922 and circadian regulation of gene expression and biological process this GO :0033558 and protein deacetylase activity and molecular function this GO :0033613 and activating transcription factor binding and molecular function this GO :0042475 and odontogenesis of dentin-containing tooth and biological process this GO :0042733 and embryonic digit morphogenesis and biological process this GO :0042826 and histone deacetylase binding and molecular function this GO :0043044 and ATP-dependent chromatin remodeling and biological process this GO :0043066 and negative regulation of apoptotic process and biological process this GO :0043234 and protein complex and cellular component this GO :0043922 and negative regulation by host of viral transcription and biological process this GO :0045087 and innate immune response and biological process this GO :0045786 and negative regulation of cell cycle and biological process this GO :0045892 and negative regulation of transcription, DNA-templated and biological process this GO :0045893 and positive regulation of transcription, DNA-templated and biological process this GO :0045944 and positive regulation of transcription from RNA polymerase II promoter and biological process this GO :0046969 and NAD-dependent histone deacetylase activity (H3-K9 specific) and molecular function this GO :0046970 and NAD-dependent histone deacetylase activity (H4-K16 specific) and molecular function this GO :0048011 and neurotrophin TRK receptor signaling pathway and biological process this GO :0060766 and negative regulation of androgen receptor signaling pathway and biological process this GO :0060789 and hair follicle placode formation and biological process this GO :0061029 and eyelid development in camera-type eye and biological process this GO :0061198 and fungiform papilla formation and biological process this GO :0070932 and histone H3 deacetylation and biological process this GO :0070933 and histone H4 deacetylation and biological process this GO :0097372 and NAD-dependent histone deacetylase activity (H3-K18 specific) and molecular function, HDAC1 and IDBG-644586 and ENSBTAG00000012698 and 404126, HDAC1 and IDBG-95712 and ENSG00000116478 and 3065, NAD-dependent histone deacetylase activity (H3-K18 specific), nuclei, this GO :0000118 and histone deacetylase complex and cellular component this GO :0000122 and negative regulation of transcription from RNA polymerase II promoter and biological process this GO :0000278 and mitotic cell cycle and biological process this GO :0000790 and nuclear chromatin and cellular component this GO :0000976 and transcription regulatory region sequence-specific DNA binding and molecular function this GO :0000978 and RNA polymerase II core promoter proximal region sequence-specific DNA binding and molecular function this GO :0000980 and RNA polymerase II distal enhancer sequence-specific DNA binding and molecular function this GO :0001047 and core promoter binding and molecular function this GO :0001103 and RNA polymerase II repressing transcription factor binding and molecular function this GO :0001106 and RNA polymerase II transcription corepressor activity and molecular function this GO :0003700 and sequence-specific DNA binding transcription factor activity and molecular function this GO :0004407 and histone deacetylase activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0005654 and nucleoplasm and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0005829 and cytosol and cellular component this GO :0006338 and chromatin remodeling and biological process this GO :0006351 and transcription, this GO :0000976: transcription regulatory region sequence-specific DNA binding, this GO :0000976: transcription regulatory region sequence-specific DNA binding and also this GO :0000978: RNA polymerase II core promoter proximal region sequence-specific DNA binding and also this GO :0000980: RNA polymerase II distal enhancer sequence-specific DNA binding and also this GO :0001047: core promoter binding and also this GO :0001103: RNA polymerase II repressing transcription factor binding and also this GO :0001106: RNA polymerase II transcription corepressor activity and also this GO :0003700: sequence-specific DNA binding transcription factor activity and also this GO :0004407: histone deacetylase activity and also this GO :0005515: protein binding and also this GO :0008134: transcription factor binding and also this GO :0019213: deacetylase activity and also this GO :0019899: enzyme binding and also this GO :0031492: nucleosomal DNA binding and also this GO :0032041: NAD-dependent histone deacetylase activity (H3-K14 specific) and also this GO :0033558: protein deacetylase activity and also this GO :0033613: activating transcription factor binding and also this GO :0042826: histone deacetylase binding and also this GO :0046969: NAD-dependent histone deacetylase activity (H3-K9 specific) and also this GO :0046970: NAD-dependent histone deacetylase activity (H4-K16 specific) and also this GO :0097372: NAD-dependent histone deacetylase activity (H3-K18 specific), this GO :0000978: RNA polymerase II core promoter proximal region sequence-specific DNA binding, this GO :0000980: RNA polymerase II distal enhancer sequence-specific DNA binding, this GO :0001047: core promoter binding, this GO :0001103: RNA polymerase II repressing transcription factor binding, this GO :0001106: RNA polymerase II transcription corepressor activity, this GO :0003700: sequence-specific DNA binding transcription factor activity, this GO :0004407: histone deacetylase activity, this GO :0005515: protein binding, this GO :0008134: transcription factor binding, this GO :0019213: deacetylase activity, this GO :0019899: enzyme binding, this GO :0031492: nucleosomal DNA binding, this GO :0032041: NAD-dependent histone deacetylase activity (H3-K14 specific), this GO :0033558: protein deacetylase activity, this GO :0033613: activating transcription factor binding, this GO :0042826: histone deacetylase binding, this GO :0046969: NAD-dependent histone deacetylase activity (H3-K9 specific), this GO :0046970: NAD-dependent histone deacetylase activity (H4-K16 specific), this GO :0097372: NAD-dependent histone deacetylase activity (H3-K18 specific), this GO N-10 and HD1 and RPD3 and RPD3L1, histone deacetylase 1 |
| Identity | 4852 |
| Gene | HDAC1 |
| Long gene name | histone deacetylase 1 |
| Synonyms gene | RPD3L1 |
| Synonyms | HD1 GON-10 |
| Locus | 1p35, 1 , 2-p35 |
| Discovery year | 1996-11-15 |
| GenBank acession | D50405 |
| Entrez gene record | 3065 |
| Pubmed identfication | 8602529 |
| RefSeq identity | NM_004964 |
| Classification | NuRD complex Histone deacetylases, class I EMSY complex SIN3 histone deacetylase complex |
| Havana BLAST/BLAT | OTTHUMG00000007529 |
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