| Also known as | IKBKG / NEMO / IKK Gamma |
| Other names | FIP-3, I-kappa-B kinase subunit gamma, I-kappa-B kinase subunit gamma, IKK-gamma, IKKAP1, IKKAP1, IKKG, IKKG, IkB kinase gamma subunit, IkB kinase subunit gamma, IkB kinase-associated protein 1, Inhibitor of nuclear factor kappa-B kinase subunit gamma, NF-kappa-B essential modifier, NF-kappa-B essential modifier, NF-kappa-B essential modulator, NF-kappa-B essential modulator, NFkappaB essential modulator, ikB kinase subunit gamma, ikB kinase-associated protein 1, incontinentia pigmenti, inhibitor of kappa light polypeptide gene enhancer in B-cells, inhibitor of nuclear factor kappa-B kinase subunit gamma, kinase gamma, NF-kappa-B essential modulator isoform a |
| Category | Antibodies |
| Subcategory | Mnoclonal antibodies |
| Gene name | IKBKG |
| Gene name synonims | N/A |
| Other gene names | AMCBX1, FIP-3, FIP3, FIP3, Fip3p, I-kappa-B kinase subunit gamma, IKBKG, IKK-gamma, IKK-gamma, IKKAP1, IKKG, IMD33, IP, IP1, IP2, IPD2, IkB kinase subunit gamma, NEMO, NEMO, NEMO, ZC2HC9, IKBKG |
| Clonality | Monoclonal |
| Immunoglobulin isotype | IgG1 |
| Clone | 46B844 |
| Host organism | Mouse (Mus musculus) |
| Species reactivity | Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby, Human (Homo sapiens) |
| Specificity and cross-reactivity | Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited, This particular antibody might cross react with speacies outside of the listed ones, A His-tagged full-length human IKK3/IKKg protein |
| Purification method | Protein G Purified |
| Form/Appearance | 0, 0, 05% sodium azide, 2% gelatin, PBS |
| Concentration | 5 mg/ml |
| Storage and shipping | For long term storage aliquot and keep the antibody at -20 degrees Celsius, Freeze-thaw cycles should be avoided in order to retain the activity of the antibody, Store at +4 degrees Celsius for short term storage |
| Tested applications: | Flow Cytometry (FC/FACS), Western Blot (WB), Immunohistochemistry (IHC - Paraffin) |
| Properties | Depending on the epitopes used human ELISA kits can be cross reactive to many other species, Human proteins, Mainly analyzed are human serum, Modern , cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies, human cell culture supernatants and biological samples, plasma, primarily , saliva, urine, , (Homo sapiens, C, C for long term storage and for short term at + 5°, Homo sapiens sapiens), If you buy Antibodies supplied by MBS mono they should be stored frozen at - 24°, humans , ssp |
| About | Each murine monoclonal anibody has his own affinity specific for the clone, Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes, Monoclonals of this antigen are available in different clones |
| Test | A/J, BALB/c, Mouse are mature after 40 days for females and 55 days for males, SCID while the CD-1 is outbred as strain, The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year, Transgenic, congenic and inbread strains are known for C57BL/6, knock-out, Mouse , mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab, or |
| Latin name | Mus musculus |
| Gene target | Monoclonal [ 46B844] (IgG1) IKBKG / NEMO / IKK Gamma |
| Short name | Mouse Monoclonal [clone 46B844] (IgG1) IKBKG / NEMO / IKK Gamma Antibody |
| Technique | Monoclonals or monoclonal antibodies, antibodies against human proteins, antibodies for, mouses, Antibody |
| Isotype | IgG1 |
| Species | Humans, Mouses, Human |
| Alternative name | kinase gamma / NEMO / IKK g (Antibody to), sapiens inhibitor on kappa light polypeptide gene enhancer in B-cells, Mouse monoclonal [clonality 46B844] (IgG1) to H |
| Alternative technique | antibodies |
| Alternative to gene target | AMCBX1 and FIP-3 and FIP3 and Fip3p and IKK-gamma and IMD33 and IP and IP1 and IP2 and IPD2 and NEMO and ZC2HC9, DNA-templated and biological process this GO :0006915 and apoptotic process and biological process this GO :0006954 and inflammatory response and biological process this GO :0006955 and immune response and biological process this GO :0006974 and cellular response to DNA damage stimulus and biological process this GO :0007249 and I-kappaB kinase/NF-kappaB signaling and biological process this GO :0007250 and activation of NF-kappaB-inducing kinase activity and biological process this GO :0007254 and JNK cascade and biological process this GO :0008385 and IkappaB kinase complex and cellular component this GO :0009615 and response to virus and biological process this GO :0016032 and viral process and biological process this GO :0019904 and protein domain specific binding and molecular function this GO :0032481 and positive regulation of type I interferon production and biological process this GO :0034134 and toll-like receptor 2 signaling pathway and biological process this GO :0034138 and toll-like receptor 3 signaling pathway and biological process this GO :0034142 and toll-like receptor 4 signaling pathway and biological process this GO :0034146 and toll-like receptor 5 signaling pathway and biological process this GO :0034162 and toll-like receptor 9 signaling pathway and biological process this GO :0034166 and toll-like receptor 10 signaling pathway and biological process this GO :0035666 and TRIF-dependent toll-like receptor signaling pathway and biological process this GO :0035872 and nucleotide-binding domain, IKBKG and IDBG-633075 and ENSBTAG00000006268 and 281855, IKBKG and IDBG-777831 and ENSG00000269335 and 8517, Ikbkg and IDBG-156458 and ENSMUSG00000004221 and 16151, kinase gamma, leucine rich repeat containing receptor signaling pathway and biological process this GO :0038095 and Fc-epsilon receptor signaling pathway and biological process this GO :0038123 and toll-like receptor TLR1:TLR2 signaling pathway and biological process this GO :0038124 and toll-like receptor TLR6:TLR2 signaling pathway and biological process this GO :0042803 and protein homodimerization activity and molecular function this GO :0042975 and peroxisome proliferator activated receptor binding and molecular function this GO :0043123 and positive regulation of I-kappaB kinase/NF-kappaB signaling and biological process this GO :0045087 and innate immune response and biological process this GO :0045944 and positive regulation of transcription from RNA polymerase II promoter and biological process this GO :0046872 and metal ion binding and molecular function this GO :0046982 and protein heterodimerization activity and molecular function this GO :0050852 and T cell receptor signaling pathway and biological process this GO :0051092 and positive regulation of NF-kappaB transcription factor activity and biological process this GO :0051403 and stress-activated MAPK cascade and biological process this GO :0070423 and nucleotide-binding oli this GO merization domain containing signaling pathway and biological process, nuclei, protein heterodimerization activity, this GO :0000187 and activation of MAPK activity and biological process this GO :0001782 and B cell homeostasis and biological process this GO :0002224 and toll-like receptor signaling pathway and biological process this GO :0002755 and MyD88-dependent toll-like receptor signaling pathway and biological process this GO :0002756 and MyD88-independent toll-like receptor signaling pathway and biological process this GO :0004871 and signal transducer activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005622 and intracellular and cellular component this GO :0005634 and nucleus and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0005829 and cytosol and cellular component this GO :0006351 and transcription, this GO :0004871: signal transducer activity, this GO :0004871: signal transducer activity and also this GO :0005515: protein binding and also this GO :0019904: protein domain specific binding and also this GO :0042803: protein homodimerization activity and also this GO :0042975: peroxisome proliferator activated receptor binding and also this GO :0046872: metal ion binding and also this GO :0046982: protein heterodimerization activity, this GO :0005515: protein binding, this GO :0019904: protein domain specific binding, this GO :0042803: protein homodimerization activity, this GO :0042975: peroxisome proliferator activated receptor binding, this GO :0046872: metal ion binding, this GO :0046982: protein heterodimerization activity, inhibitor of kappa light polypeptide gene enhancer in B-cells |
| Identity | 5961 |
| Gene | IKBKG |
| Long gene name | inhibitor of nuclear factor kappa B kinase subunit gamma |
| Synonyms gene | IP2 IP1 |
| Synonyms gene name | incontinentia pigmenti inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma |
| Synonyms | IKK-gamma NEMO Fip3p FIP-3 FIP3 ZC2HC9 |
| Locus | Xq28 |
| Discovery year | 1998-09-30 |
| GenBank acession | AF074382 |
| Entrez gene record | 8517 |
| Pubmed identfication | 9751060 10087442 11590134 |
| RefSeq identity | NM_003639 |
| Classification | Zinc fingers C2HC-type |
| Havana BLAST/BLAT | OTTHUMG00000024234 |
| Locus Specific Databases | IKBKGbase: Mutation registry for Nemo deficiency Mental Retardation database LRG_70 |
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