| Also known as | ITGAV/Integrin Alpha V/CD51 |
| Other names | CD_antigen: CD51Cleaved into the following 2 chains:Integrin alpha-V heavy chain, Integrin alpha-V, Integrin alpha-V light chain, Vitronectin receptor subunit alpha, alpha V, alpha V (vitronectin receptor, alpha polypeptide, antigen CD51), antigen identified by monoclonal antibody L230, integrin, integrin, integrin alpha-V, integrin alphaVbeta3, vitronectin receptor subunit alpha, integrin alpha-V isoform 1 |
| Category | Antibodies |
| Subcategory | Mnoclonal antibodies |
| Gene name | ITGAV |
| Gene name synonims | N/A |
| Other gene names | CD51, ITGAV, MSK8, MSK8, VNRA, VNRA, VTNR, ITGAV |
| Clonality | Monoclonal |
| Immunoglobulin isotype | IgG1 |
| Clone | N/A |
| Host organism | Mouse (Mus musculus) |
| Species reactivity | Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby, Human (Homo sapiens) |
| Specificity and cross-reactivity | Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited, This particular antibody might cross react with speacies outside of the listed ones, Recognizes human CD51 |
| Purification method | Purified |
| Form/Appearance | 0, pH 7, 1% sodium azide, 4, PBS |
| Concentration | 1 miligram per 1 mililiter |
| Storage and shipping | Cycles of freezing/defrosting can damage the peptide chains of the antibodies thus reducing the activity, Short term storage of the antibody can be done at +4 degrees Celsius, keep the antibody at -20 degrees Celsius, For long term storage |
| Tested applications: | Flow Cytometry (FC/FACS), Functional Assay, IHC - Frozen), Immunofluorescence (IF), Immunoprecipitation (IP), Immunohistochemistry (IHC - Paraffin |
| Description | - or alpha protein sometimes glycoprotein present in blood, The Mouse Monoclonal (IgG1) ITGAV/Integrin Alpha V/CD51 Antibody is a &alpha |
| Properties | Depending on the epitopes used human ELISA kits can be cross reactive to many other species, Human proteins, Mainly analyzed are human serum, Modern , cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies, human cell culture supernatants and biological samples, plasma, primarily , saliva, urine, , (Homo sapiens, C, C for long term storage and for short term at + 5°, Homo sapiens sapiens), If you buy Antibodies supplied by MBS mono they should be stored frozen at - 24°, humans , ssp |
| About | Each murine monoclonal anibody has his own affinity specific for the clone, Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes, Monoclonals of this antigen are available in different clones |
| Test | A/J, BALB/c, Mouse are mature after 40 days for females and 55 days for males, SCID while the CD-1 is outbred as strain, The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year, Transgenic, congenic and inbread strains are known for C57BL/6, knock-out, Mouse , mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab, or |
| Latin name | Mus musculus |
| Gene target | Monoclonal (IgG1) ITGAV/Integrin Alpha V/CD51 |
| Short name | Mouse Monoclonal (IgG1) ITGAV/Integrin Alpha V/CD51 Antibody |
| Technique | Monoclonals or monoclonal antibodies, antibodies against human proteins, antibodies for, mouses, Antibody |
| Isotype | IgG1 |
| Species | Humans, Mouses, Human |
| Alternative name | a V/Integrin a V/CD51 (Antibody to), sapiens integrin, Mouse monoclonal (IgG1) to H |
| Alternative technique | antibodies |
| Alternative to gene target | CD51 and MSK8 and VNRA and VTNR, Cell surfaces, ITGAV and IDBG-639711 and ENSBTAG00000019929 and 281875, ITGAV and IDBG-77054 and ENSG00000138448 and 3685, Itgav and IDBG-184247 and ENSMUSG00000027087 and 16410, TAP-dependent and biological process this GO :0005080 and protein kinase C binding and molecular function this GO :0005245 and voltage-gated calcium channel activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005886 and plasma membrane and cellular component this GO :0005887 and integral component of plasma membrane and cellular component this GO :0007155 and cell adhesion and biological process this GO :0007160 and cell-matrix adhesion and biological process this GO :0007229 and integrin-mediated signaling pathway and biological process this GO :0007411 and axon guidance and biological process this GO :0007596 and blood coagulation and biological process this GO :0008284 and positive regulation of cell proliferation and biological process this GO :0008305 and integrin complex and cellular component this GO :0009615 and response to virus and biological process this GO :0009897 and external side of plasma membrane and cellular component this GO :0009986 and cell surface and cellular component this GO :0010745 and negative regulation of macrophage derived foam cell differentiation and biological process this GO :0010888 and negative regulation of lipid storage and biological process this GO :0016020 and membrane and cellular component this GO :0030198 and extracellular matrix organization and biological process this GO :0030335 and positive regulation of cell migration and biological process this GO :0031589 and cell-substrate adhesion and biological process this GO :0031994 and insulin-like growth factor I binding and molecular function this GO :0032369 and negative regulation of lipid transport and biological process this GO :0033690 and positive regulation of osteoblast proliferation and biological process this GO :0035867 and alphav-beta3 integrin-IGF-1-IGF1R complex and cellular component this GO :0042590 and antigen processing and presentation of exogenous peptide antigen via MHC class I and biological process this GO :0043277 and apoptotic cell clearance and biological process this GO :0045087 and innate immune response and biological process this GO :0045335 and pha this GO cytic vesicle and cellular component this GO :0045715 and negative regulation of low-density lipoprotein particle receptor biosynthetic process and biological process this GO :0045785 and positive regulation of cell adhesion and biological process this GO :0046718 and viral entry into host cell and biological process this GO :0046872 and metal ion binding and molecular function this GO :0050431 and transforming growth factor beta binding and molecular function this GO :0050748 and negative regulation of lipoprotein metabolic process and biological process this GO :0050764 and regulation of pha this GO cytosis and biological process this GO :0050900 and leukocyte migration and biological process this GO :0052066 and entry of symbiont into host cell by promotion of host pha this GO cytosis and biological process this GO :0070062 and extracellular vesicular exosome and cellular component this GO :0070371 and ERK1 and ERK2 cascade and biological process this GO :0070588 and calcium ion transmembrane transport and biological process this GO :0097192 and extrinsic apoptotic signaling pathway in absence of ligand and biological process this GO :2000425 and regulation of apoptotic cell clearance and biological process this GO :2000536 and negative regulation of entry of bacterium into host cell and biological process this GO :2001237 and negative regulation of extrinsic apoptotic signaling pathway and biological process, alpha V, this GO :0001525 and angiogenesis and biological process this GO :0001568 and blood vessel development and biological process this GO :0001618 and virus receptor activity and molecular function this GO :0001846 and opsonin binding and molecular function this GO :0002474 and antigen processing and presentation of peptide antigen via MHC class I and biological process this GO :0002479 and antigen processing and presentation of exogenous peptide antigen via MHC class I, this GO :0001618: virus receptor activity, this GO :0001618: virus receptor activity and also this GO :0001846: opsonin binding and also this GO :0005080: protein kinase C binding and also this GO :0005245: voltage-gated calcium channel activity and also this GO :0005515: protein binding and also this GO :0031994: insulin-like growth factor I binding and also this GO :0046872: metal ion binding and also this GO :0050431: transforming growth factor beta binding, this GO :0001846: opsonin binding, this GO :0005080: protein kinase C binding, this GO :0005245: voltage-gated calcium channel activity, this GO :0005515: protein binding, this GO :0031994: insulin-like growth factor I binding, this GO :0046872: metal ion binding, this GO :0050431: transforming growth factor beta binding, transforming growth factor beta binding, integrin |
| Identity | 6150 |
| Gene | ITGAV |
| Long gene name | integrin subunit alpha V |
| Synonyms gene | VNRA MSK8 VTNR |
| Synonyms gene name | alpha V , alpha V (vitronectin receptor, alpha polypeptide, antigen CD51) integrin, antigen identified by monoclonal antibody L230 vitronectin receptor integrin |
| Synonyms | CD51 |
| Locus | 2q32, 1 |
| Discovery year | 1988-07-19 |
| Entrez gene record | 3685 |
| Pubmed identfication | 2454952 |
| RefSeq identity | NM_002210 |
| Classification | Integrin alpha subunits CD molecules |
| Havana BLAST/BLAT | OTTHUMG00000132635 |
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