| Also known as | HTT / Huntingtin |
| Other names | HD protein, Huntingtin, Huntington disease protein, huntingtin, huntingtin, huntington disease protein, huntingtin |
| Category | Antibodies |
| Subcategory | Mnoclonal antibodies |
| Gene name | HTT |
| Gene name synonims | N/A |
| Other gene names | HD, HD, HD protein, HTT, IT15, IT15, HTT |
| Clonality | Monoclonal |
| Immunoglobulin isotype | IgG2a, k |
| Clone | 3F1 |
| Host organism | Mouse (Mus musculus) |
| Species reactivity | Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby, Human (Homo sapiens) |
| Specificity and cross-reactivity | Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited, This particular antibody might cross react with speacies outside of the listed ones, Human Huntingtin |
| Purification method | Protein A Purified |
| Form/Appearance | pH 7, 2, PBS |
| Concentration | 48 mg/ml |
| Storage and shipping | For long term storage aliquot and keep the antibody at -20 degrees Celsius, Freeze-thaw cycles should be avoided in order to retain the activity of the antibody, Store at +4 degrees Celsius for short term storage |
| Tested applications: | ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC - Paraffin) |
| Properties | Depending on the epitopes used human ELISA kits can be cross reactive to many other species, Human proteins, Mainly analyzed are human serum, Modern , cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies, human cell culture supernatants and biological samples, plasma, primarily , saliva, urine, , (Homo sapiens, C, C for long term storage and for short term at + 5°, Homo sapiens sapiens), If you buy Antibodies supplied by MBS mono they should be stored frozen at - 24°, humans , ssp |
| About | Each murine monoclonal anibody has his own affinity specific for the clone, Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes, Monoclonals of this antigen are available in different clones |
| Test | A/J, BALB/c, Mouse are mature after 40 days for females and 55 days for males, SCID while the CD-1 is outbred as strain, The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year, Transgenic, congenic and inbread strains are known for C57BL/6, knock-out, Mouse , mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab, or |
| Latin name | Mus musculus |
| Gene target | Monoclonal [ 3F1] (IgG2a, k) HTT / Huntingtin |
| Short name | Mouse Monoclonal [clone 3F1] (IgG2a, k) HTT / Huntingtin Antibody |
| Technique | Monoclonals or monoclonal antibodies, antibodies against human proteins, antibodies for, mouses, Antibody |
| Isotype | IgG2a |
| Species | Humans, Mouses, Human |
| Alternative name | sapiens huntingtin / Huntingtin (Antibody to), Mouse monoclonal [clonality 3F1] (IgG2a, k) to H |
| Alternative technique | antibodies |
| Alternative to gene target | HD and IT15, HTT and IDBG-643549 and ENSBTAG00000001506 and 615059, HTT and IDBG-7852 and ENSG00000197386 and 3064, Htt and IDBG-156033 and ENSMUSG00000029104 and 15194, diazepam binding, nuclei, this GO :0000050 and urea cycle and biological process this GO :0000052 and citrulline metabolic process and biological process this GO :0000132 and establishment of mitotic spindle orientation and biological process this GO :0002039 and p53 binding and molecular function this GO :0005488 and binding and molecular function this GO :0005515 and protein binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0005739 and mitochondrion and cellular component this GO :0005770 and late endosome and cellular component this GO :0005776 and autophagic vacuole and cellular component this GO :0005783 and endoplasmic reticulum and cellular component this GO :0005794 and this GO lgi apparatus and cellular component this GO :0005829 and cytosol and cellular component this GO :0006606 and protein import into nucleus and biological process this GO :0006839 and mitochondrial transport and biological process this GO :0006888 and ER to this GO lgi vesicle-mediated transport and biological process this GO :0006890 and retrograde vesicle-mediated transport, this GO :0002039: p53 binding, this GO :0002039: p53 binding and also this GO :0005488: binding and also this GO :0005515: protein binding and also this GO :0008134: transcription factor binding and also this GO :0034452: dynactin binding and also this GO :0042802: identical protein binding and also this GO :0045505: dynein intermediate chain binding and also this GO :0048487: beta-tubulin binding and also this GO :0050809: diazepam binding, this GO :0005488: binding, this GO :0005515: protein binding, this GO :0008134: transcription factor binding, this GO :0034452: dynactin binding, this GO :0042802: identical protein binding, this GO :0045505: dynein intermediate chain binding, this GO :0048487: beta-tubulin binding, this GO :0050809: diazepam binding, this GO lgi to ER and biological process this GO :0006915 and apoptotic process and biological process this GO :0007005 and mitochondrion organization and biological process this GO :0007029 and endoplasmic reticulum organization and biological process this GO :0007030 and this GO lgi organization and biological process this GO :0007212 and dopamine receptor signaling pathway and biological process this GO :0007283 and spermatogenesis and biological process this GO :0007369 and gastrulation and biological process this GO :0007417 and central nervous system development and biological process this GO :0007420 and brain development and biological process this GO :0007569 and cell aging and biological process this GO :0007611 and learning or memory and biological process this GO :0007612 and learning and biological process this GO :0007625 and grooming behavior and biological process this GO :0007626 and locomotory behavior and biological process this GO :0008088 and axon car this GO transport and biological process this GO :0008134 and transcription factor binding and molecular function this GO :0008306 and associative learning and biological process this GO :0008340 and determination of adult lifespan and biological process this GO :0008542 and visual learning and biological process this GO :0009653 and anatomical structure morphogenesis and biological process this GO :0009952 and anterior/posterior pattern specification and biological process this GO :0016023 and cytoplasmic membrane-bounded vesicle and cellular component this GO :0016197 and endosomal transport and biological process this GO :0016234 and inclusion body and cellular component this GO :0019244 and lactate biosynthetic process from pyruvate and biological process this GO :0019805 and quinolinate biosynthetic process and biological process this GO :0021756 and striatum development and biological process this GO :0021988 and olfactory lobe development and biological process this GO :0021990 and neural plate formation and biological process this GO :0022008 and neurogenesis and biological process this GO :0030072 and peptide hormone secretion and biological process this GO :0030073 and insulin secretion and biological process this GO :0030424 and axon and cellular component this GO :0030425 and dendrite and cellular component this GO :0030659 and cytoplasmic vesicle membrane and cellular component this GO :0034047 and regulation of protein phosphatase type 2A activity and biological process this GO :0034452 and dynactin binding and molecular function this GO :0035176 and social behavior and biological process this GO :0042445 and hormone metabolic process and biological process this GO :0042802 and identical protein binding and molecular function this GO :0043066 and negative regulation of apoptotic process and biological process this GO :0043234 and protein complex and cellular component this GO :0043524 and negative regulation of neuron apoptotic process and biological process this GO :0045505 and dynein intermediate chain binding and molecular function this GO :0046902 and regulation of mitochondrial membrane permeability and biological process this GO :0047496 and vesicle transport along microtubule and biological process this GO :0048167 and regulation of synaptic plasticity and biological process this GO :0048341 and paraxial mesoderm formation and biological process this GO :0048487 and beta-tubulin binding and molecular function this GO :0048513 and organ development and biological process this GO :0048666 and neuron development and biological process this GO :0050809 and diazepam binding and molecular function this GO :0051402 and neuron apoptotic process and biological process this GO :0051592 and response to calcium ion and biological process this GO :0051881 and regulation of mitochondrial membrane potential and biological process this GO :0051938 and L-glutamate import and biological process this GO :0055072 and iron ion homeostasis and biological process this GO :1901215 and negative regulation of neuron death and biological process this GO :2001237 and negative regulation of extrinsic apoptotic signaling pathway and biological process, huntingtin |
| Identity | 4851 |
| Gene | HTT |
| Long gene name | huntingtin |
| Synonyms gene | HD |
| Synonyms gene name | huntingtin (Huntington disease) |
| Synonyms | IT15 |
| Locus | 4p16, 3 |
| Discovery year | 1986-01-01 |
| GenBank acession | L12392 |
| Entrez gene record | 3064 |
| Pubmed identfication | 8458085 |
| RefSeq identity | NM_002111 |
| Classification | Endogenous ligands |
| Havana BLAST/BLAT | OTTHUMG00000159916 |
| Locus Specific Databases | LOVD - Leiden Open Variation Database LOVD Mendelian genes - huntingin (HTT) LRG_763 |
Technique
Supplier
Species
Label
Iso Type
Host
Tissue