| Also known as | SLC11A2 / DMT1 |
| Other names | DMT-1, DMT-1, Divalent cation transporter 1, Divalent metal transporter 1, NRAMP 2, Natural resistance-associated macrophage protein 2, Solute carrier family 11 member 2, divalent cation transporter 1, member 2, member 2, natural resistance-associated macrophage protein 2, solute carrier family 11 (proton-coupled divalent metal ion transporter), solute carrier family 11 (proton-coupled divalent metal ion transporters), solute carrier family 11 member 2, natural resistance-associated macrophage protein 2 isoform 3 |
| Category | Antibodies |
| Subcategory | Mnoclonal antibodies |
| Gene name | SLC11A2 |
| Gene name synonims | DMT1 |
| Other gene names | DCT1, DCT1, DMT-1, DMT1, DMT1, NRAMP 2, NRAMP2, NRAMP2, SLC11A2, SLC11A2 |
| Clonality | Monoclonal |
| Immunoglobulin isotype | IgG2a, k |
| Clone | 4C6 |
| Host organism | Mouse (Mus musculus) |
| Species reactivity | Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby, Human (Homo sapiens) |
| Specificity and cross-reactivity | Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited, This particular antibody might cross react with speacies outside of the listed ones, Human SLC11A2 |
| Purification method | Protein A Purified |
| Form/Appearance | Sourced in Ascites, pH 7, 2, PBS |
| Concentration | 36 mg/ml |
| Storage and shipping | For long term storage aliquot and keep the antibody at -20 degrees Celsius, Freeze-thaw cycles should be avoided in order to retain the activity of the antibody, Store at +4 degrees Celsius for short term storage |
| Tested applications: | ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC - Paraffin) |
| Properties | Depending on the epitopes used human ELISA kits can be cross reactive to many other species, Human proteins, Mainly analyzed are human serum, Modern , cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies, human cell culture supernatants and biological samples, plasma, primarily , saliva, urine, , (Homo sapiens, C, C for long term storage and for short term at + 5°, Homo sapiens sapiens), If you buy Antibodies supplied by MBS mono they should be stored frozen at - 24°, humans , ssp |
| About | Each murine monoclonal anibody has his own affinity specific for the clone, Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes, Monoclonals of this antigen are available in different clones |
| Test | A/J, BALB/c, Mouse are mature after 40 days for females and 55 days for males, SCID while the CD-1 is outbred as strain, The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year, Transgenic, congenic and inbread strains are known for C57BL/6, knock-out, Mouse , mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab, or |
| Latin name | Mus musculus |
| Gene target | Monoclonal [ 4C6] (IgG2a, k) SLC11A2 / DMT1 |
| Short name | Mouse Monoclonal [clone 4C6] (IgG2a, k) SLC11A2 / DMT1 Antibody |
| Technique | Monoclonals or monoclonal antibodies, antibodies against human proteins, antibodies for, mouses, Antibody |
| Isotype | IgG2a |
| Species | Humans, Mouses, Human |
| Alternative name | member 2 / DMT1 (Antibody to), sapiens solute carrier family 11 (proton-coupled divalent metal ion transporters), Mouse monoclonal [clonality 4C6] (IgG2a, k) to H |
| Alternative technique | antibodies |
| Alternative to gene target | DCT1 and DMT1 and NRAMP2, SLC11A2 and IDBG-32924 and ENSG00000110911 and 4891, Slc11a2 and IDBG-184534 and ENSMUSG00000023030 and 18174, cobalt ion binding, member 2, nuclei, this GO :0000041 and transition metal ion transport and biological process this GO :0001666 and response to hypoxia and biological process this GO :0003032 and detection of oxygen and biological process this GO :0005215 and transporter activity and molecular function this GO :0005375 and copper ion transmembrane transporter activity and molecular function this GO :0005381 and iron ion transmembrane transporter activity and molecular function this GO :0005384 and manganese ion transmembrane transporter activity and molecular function this GO :0005385 and zinc ion transmembrane transporter activity and molecular function this GO :0005506 and iron ion binding and molecular function this GO :0005507 and copper ion binding and molecular function this GO :0005515 and protein binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0005764 and lysosome and cellular component this GO :0005765 and lysosomal membrane and cellular component this GO :0005768 and endosome and cellular component this GO :0005769 and early endosome and cellular component this GO :0005770 and late endosome and cellular component this GO :0005773 and vacuole and cellular component this GO :0005802 and trans- this GO lgi network and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0005887 and integral component of plasma membrane and cellular component this GO :0005903 and brush border and cellular component this GO :0006778 and porphyrin-containing compound metabolic process and biological process this GO :0006779 and porphyrin-containing compound biosynthetic process and biological process this GO :0006783 and heme biosynthetic process and biological process this GO :0006810 and transport and biological process this GO :0006824 and cobalt ion transport and biological process this GO :0006825 and copper ion transport and biological process this GO :0006826 and iron ion transport and biological process this GO :0006828 and manganese ion transport and biological process this GO :0006878 and cellular copper ion homeostasis and biological process this GO :0006879 and cellular iron ion homeostasis and biological process this GO :0006919 and activation of cysteine-type endopeptidase activity involved in apoptotic process and biological process this GO :0007611 and learning or memory and biological process this GO :0008270 and zinc ion binding and molecular function this GO :0009986 and cell surface and cellular component this GO :0010039 and response to iron ion and biological process this GO :0010042 and response to manganese ion and biological process this GO :0010288 and response to lead ion and biological process this GO :0012505 and endomembrane system and cellular component this GO :0015078 and hydrogen ion transmembrane transporter activity and molecular function this GO :0015086 and cadmium ion transmembrane transporter activity and molecular function this GO :0015087 and cobalt ion transmembrane transporter activity and molecular function this GO :0015093 and ferrous iron transmembrane transporter activity and molecular function this GO :0015094 and lead ion transmembrane transporter activity and molecular function this GO :0015099 and nickel cation transmembrane transporter activity and molecular function this GO :0015100 and vanadium ion transmembrane transporter activity and molecular function this GO :0015295 and solute:proton symporter activity and molecular function this GO :0015675 and nickel cation transport and biological process this GO :0015676 and vanadium ion transport and biological process this GO :0015684 and ferrous iron transport and biological process this GO :0015692 and lead ion transport and biological process this GO :0015992 and proton transport and biological process this GO :0016020 and membrane and cellular component this GO :0016021 and integral component of membrane and cellular component this GO :0016151 and nickel cation binding and molecular function this GO :0016324 and apical plasma membrane and cellular component this GO :0022890 and inorganic cation transmembrane transporter activity and molecular function this GO :0030145 and manganese ion binding and molecular function this GO :0031410 and cytoplasmic vesicle and cellular component this GO :0031902 and late endosome membrane and cellular component this GO :0034599 and cellular response to oxidative stress and biological process this GO :0035444 and nickel cation transmembrane transport and biological process this GO :0045177 and apical part of cell and cellular component this GO :0045178 and basal part of cell and cellular component this GO :0046686 and response to cadmium ion and biological process this GO :0046870 and cadmium ion binding and molecular function this GO :0048471 and perinuclear region of cytoplasm and cellular component this GO :0048813 and dendrite morphogenesis and biological process this GO :0048821 and erythrocyte development and biological process this GO :0050897 and cobalt ion binding and molecular function this GO :0055037 and recycling endosome and cellular component this GO :0055085 and transmembrane transport and biological process this GO :0060586 and multicellular organismal iron ion homeostasis and biological process this GO :0070574 and cadmium ion transmembrane transport and biological process this GO :0070627 and ferrous iron import and biological process this GO :0070826 and paraferritin complex and cellular component this GO :0071281 and cellular response to iron ion and biological process this GO :0071356 and cellular response to tumor necrosis factor and biological process this GO :0071421 and manganese ion transmembrane transport and biological process this GO :0071456 and cellular response to hypoxia and biological process this GO :0071577 and zinc ion transmembrane transport and biological process this GO :1902600 and hydrogen ion transmembrane transport and biological process this GO :1902861 and copper ion import into cell and biological process, this GO :0005215: transporter activity, this GO :0005215: transporter activity and also this GO :0005375: copper ion transmembrane transporter activity and also this GO :0005381: iron ion transmembrane transporter activity and also this GO :0005384: manganese ion transmembrane transporter activity and also this GO :0005385: zinc ion transmembrane transporter activity and also this GO :0005506: iron ion binding and also this GO :0005507: copper ion binding and also this GO :0005515: protein binding and also this GO :0008270: zinc ion binding and also this GO :0015078: hydrogen ion transmembrane transporter activity and also this GO :0015086: cadmium ion transmembrane transporter activity and also this GO :0015087: cobalt ion transmembrane transporter activity and also this GO :0015093: ferrous iron transmembrane transporter activity and also this GO :0015094: lead ion transmembrane transporter activity and also this GO :0015099: nickel cation transmembrane transporter activity and also this GO :0015100: vanadium ion transmembrane transporter activity and also this GO :0015295: solute:proton symporter activity and also this GO :0016151: nickel cation binding and also this GO :0022890: inorganic cation transmembrane transporter activity and also this GO :0030145: manganese ion binding and also this GO :0046870: cadmium ion binding and also this GO :0050897: cobalt ion binding, this GO :0005375: copper ion transmembrane transporter activity, this GO :0005381: iron ion transmembrane transporter activity, this GO :0005384: manganese ion transmembrane transporter activity, this GO :0005385: zinc ion transmembrane transporter activity, this GO :0005506: iron ion binding, this GO :0005507: copper ion binding, this GO :0005515: protein binding, this GO :0008270: zinc ion binding, this GO :0015078: hydrogen ion transmembrane transporter activity, this GO :0015086: cadmium ion transmembrane transporter activity, this GO :0015087: cobalt ion transmembrane transporter activity, this GO :0015093: ferrous iron transmembrane transporter activity, this GO :0015094: lead ion transmembrane transporter activity, this GO :0015099: nickel cation transmembrane transporter activity, this GO :0015100: vanadium ion transmembrane transporter activity, this GO :0015295: solute:proton symporter activity, this GO :0016151: nickel cation binding, this GO :0022890: inorganic cation transmembrane transporter activity, this GO :0030145: manganese ion binding, this GO :0046870: cadmium ion binding, this GO :0050897: cobalt ion binding, solute carrier family 11 (proton-coupled divalent metal ion transporters) |
| Identity | 10908 |
| Gene | SLC11A2 |
| Long gene name | solute carrier family 11 member 2 |
| Synonyms gene | NRAMP2 |
| Synonyms gene name | member 2 , solute carrier family 11 (proton-coupled divalent metal ion transporter) |
| Synonyms | DCT1 DMT1 |
| Locus | 12q13, 12 |
| Discovery year | 1995-12-19 |
| GenBank acession | AB015355 |
| Entrez gene record | 4891 |
| Pubmed identfication | 7613023 |
| Classification | Solute carriers |
| Havana BLAST/BLAT | OTTHUMG00000169493 |
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