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Mouse Monoclonal [clone 2E11] (IgG2a) to Human MCL1 / MCL 1 Antibody

Mouse Monoclonal [clone 2E11] (IgG2a) to Human MCL1 / MCL 1 Antibody size: 0.05 ml 597

Supplier MBS MONO
Price 597
Size 0.05 ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Also known asMCL1 / MCL 1
Other names Bcl-2-like protein 3, Bcl-2-related protein EAT/mcl1, Bcl2-L-3, Induced myeloid leukemia cell differentiation protein Mcl-1, bcl-2-like protein 3, bcl-2-related protein EAT/mcl1, induced myeloid leukemia cell differentiation protein Mcl-1, mcl1/EAT, myeloid cell leukemia 1, myeloid cell leukemia ES, myeloid cell leukemia sequence 1 (BCL2-related), induced myeloid leukemia cell differentiation protein Mcl-1 isoform 1
CategoryAntibodies
SubcategoryMnoclonal antibodies
Gene nameMCL1
Gene name synonimsMCL 1
Other gene names BCL2L3, BCL2L3, Bcl2-L-3, EAT, MCL1, MCL1-ES, MCL1L, MCL1S, Mcl-1, TM, bcl2-L-3, mcl1/EAT, MCL1
ClonalityMonoclonal
Immunoglobulin isotypeIgG2a
Clone200000000000
Host organismMouse (Mus musculus)
Species reactivity Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby, Human (Homo sapiens)
Specificity and cross-reactivity Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited, This particular antibody might cross react with speacies outside of the listed ones, Human MCL 1
Purification methodProtein A/G Purified
Form/Appearance 0, 1% BSA, 50% glycerol, pH 7, 02% sodium azide, 3, PBS
Concentration89 mg/ml
Storage and shipping Minimize freezing and thawing, the antibody should be kept at -20 degrees Celsius, For optimal long term storage
Tested applications: Flow Cytometry (FC/FACS), Immunofluorescence (IF), Western Blot (WB), Immunohistochemistry (IHC - Paraffin)
Properties Depending on the epitopes used human ELISA kits can be cross reactive to many other species, Human proteins, Mainly analyzed are human serum, Modern , cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies, human cell culture supernatants and biological samples, plasma, primarily , saliva, urine,  , (Homo sapiens, C, C for long term storage and for short term at + 5°, Homo sapiens sapiens), If you buy Antibodies supplied by MBS mono they should be stored frozen at - 24°, humans , ssp
About Each murine monoclonal anibody has his own affinity specific for the clone, Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes, Monoclonals of this antigen are available in different clones
Test A/J, BALB/c, Mouse are mature after 40 days for females and 55 days for males, SCID while the CD-1 is outbred as strain, The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year, Transgenic, congenic and inbread strains are known for C57BL/6, knock-out, Mouse , mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab, or 
Latin nameMus musculus
Gene targetMonoclonal [ 2E11] (IgG2a) MCL1 / MCL 1
Short nameMouse Monoclonal [clone 2E11] (IgG2a) MCL1 / MCL 1 Antibody
Technique Monoclonals or monoclonal antibodies, antibodies against human proteins, antibodies for, mouses, Antibody
IsotypeIgG2a
Species Humans, Mouses, Human
Alternative name sapiens myeloid cell leukemia sequence 1 (BCL2-related) / MCL 1 (Antibody to), Mouse monoclonal [clonality 2E11] (IgG2a) to H
Alternative techniqueantibodies
Alternative to gene target BH3 domain binding, MCL1 and IDBG-102145 and ENSG00000143384 and 4170, Mcl1 and IDBG-173221 and ENSMUSG00000038612 and 17210, bcl2-L-3 and BCL2L3 and EAT and Mcl-1 and MCL1-ES and mcl1/EAT and MCL1L and MCL1S and TM, nuclei, this GO :0001709 and cell fate determination and biological process this GO :0005515 and protein binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0005654 and nucleoplasm and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0005739 and mitochondrion and cellular component this GO :0005741 and mitochondrial outer membrane and cellular component this GO :0005759 and mitochondrial matrix and cellular component this GO :0005829 and cytosol and cellular component this GO :0007275 and multicellular organismal development and biological process this GO :0008630 and intrinsic apoptotic signaling pathway in response to DNA damage and biological process this GO :0008637 and apoptotic mitochondrial changes and biological process this GO :0015266 and protein channel activity and molecular function this GO :0016020 and membrane and cellular component this GO :0016021 and integral component of membrane and cellular component this GO :0019725 and cellular homeostasis and biological process this GO :0034097 and response to cytokine and biological process this GO :0042803 and protein homodimerization activity and molecular function this GO :0042981 and regulation of apoptotic process and biological process this GO :0043066 and negative regulation of apoptotic process and biological process this GO :0046982 and protein heterodimerization activity and molecular function this GO :0051434 and BH3 domain binding and molecular function this GO :0071806 and protein transmembrane transport and biological process this GO :0097136 and Bcl-2 family protein complex and cellular component this GO :0097192 and extrinsic apoptotic signaling pathway in absence of ligand and biological process this GO :0097194 and execution phase of apoptosis and biological process this GO :1900118 and negative regulation of execution phase of apoptosis and biological process this GO :2000811 and negative regulation of anoikis and biological process this GO :2001020 and regulation of response to DNA damage stimulus and biological process this GO :2001240 and negative regulation of extrinsic apoptotic signaling pathway in absence of ligand and biological process this GO :2001243 and negative regulation of intrinsic apoptotic signaling pathway and biological process, this GO :0005515: protein binding, this GO :0005515: protein binding and also this GO :0015266: protein channel activity and also this GO :0042803: protein homodimerization activity and also this GO :0046982: protein heterodimerization activity and also this GO :0051434: BH3 domain binding, this GO :0015266: protein channel activity, this GO :0042803: protein homodimerization activity, this GO :0046982: protein heterodimerization activity, this GO :0051434: BH3 domain binding, myeloid cell leukemia sequence 1 (BCL2-related)
Identity 6943
Gene MCL1
Long gene name BCL2 family apoptosis regulator
Synonyms gene name myeloid cell leukemia sequence 1 (BCL2-related) myeloid cell leukemia 1
Synonyms BCL2L3 Mcl-1
Locus 1q21, 2
Discovery year 1993-11-09
GenBank acession BC017197
Entrez gene record 4170
Pubmed identfication 7682708 7835896
RefSeq identity NM_021960
Classification BCL2 family
Havana BLAST/BLAT OTTHUMG00000034867

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