| Also known as | EPHA2 / EPH Receptor A2 |
| Other names | EPH receptor A2, Ephrin type-A receptor 2, Epithelial cell kinase, Tyrosine-protein kinase receptor ECK, ephrin type-A receptor 2, epithelial cell receptor protein tyrosine kinase, soluble EPHA2 variant 1, tyrosine-protein kinase receptor ECK, ephrin type-A receptor 2 |
| Category | Antibodies |
| Subcategory | Mnoclonal antibodies |
| Gene name | EPHA2 |
| Gene name synonims | N/A |
| Other gene names | ARCC2, CTPA, CTPP1, CTRCT6, ECK, ECK, EPHA2, EPHA2 |
| Clonality | Monoclonal |
| Immunoglobulin isotype | IgG2b, k |
| Clone | 3D7 |
| Host organism | Mouse (Mus musculus) |
| Species reactivity | Due to limited knowledge and inability for testing each and every species, Mouse (Mus musculus), the reactivity of the antibody may extend to other species which are not listed hereby, Human (Homo sapiens) |
| Specificity and cross-reactivity | Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited, This particular antibody might cross react with speacies outside of the listed ones, N/A |
| Purification method | Protein G Purified |
| Form/Appearance | 0, Sourced in Ascites, pH 7, 1% sodium azide, 4, PBS |
| Concentration | 1 miligram per 1 mililiter |
| Storage and shipping | Cycles of freezing/defrosting can damage the peptide chains of the antibodies thus reducing the activity, Short term storage of the antibody can be done at +4 degrees Celsius, keep the antibody at -20 degrees Celsius, For long term storage |
| Tested applications: | ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC - Paraffin) |
| Properties | Depending on the epitopes used human ELISA kits can be cross reactive to many other species, Human proteins, Mainly analyzed are human serum, Modern , cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies, human cell culture supernatants and biological samples, plasma, primarily , saliva, urine, , (Homo sapiens, C, C for long term storage and for short term at + 5°, Homo sapiens sapiens), If you buy Antibodies supplied by MBS mono they should be stored frozen at - 24°, humans , ssp |
| About | Each murine monoclonal anibody has his own affinity specific for the clone, Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes, Monoclonals of this antigen are available in different clones |
| Test | A/J, BALB/c, Mouse are mature after 40 days for females and 55 days for males, SCID while the CD-1 is outbred as strain, The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year, Transgenic, congenic and inbread strains are known for C57BL/6, knock-out, Mouse , mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab, or |
| Latin name | Mus musculus |
| Gene target | Monoclonal [ 3D7] (IgG2b, k) EPHA2 / EPH Receptor A2 |
| Short name | Mouse Monoclonal [clone 3D7] (IgG2b, k) EPHA2 / EPH Receptor A2 Antibody |
| Technique | Monoclonals or monoclonal antibodies, antibodies against human proteins, antibodies for, mouses, Antibody |
| Isotype | IgG2b |
| Species | Humans, Mouses, Human |
| Alternative name | sapiens EPH receptor A2 / EPH Receptor A2 (Antibody to), Mouse monoclonal [clonality 3D7] (IgG2b, k) to H |
| Alternative technique | antibodies |
| Alternative to gene target | ARCC2 and CTPA and CTPP1 and CTRCT6 and ECK, Cell surfaces, EPHA2 and IDBG-645870 and ENSBTAG00000000815 and 512798, EPHA2 and IDBG-91407 and ENSG00000142627 and 1969, Epha2 and IDBG-202005 and ENSMUSG00000006445 and 13836, this GO :0001501 and skeletal system development and biological process this GO :0001525 and angiogenesis and biological process this GO :0001568 and blood vessel development and biological process this GO :0001570 and vasculogenesis and biological process this GO :0001649 and osteoblast differentiation and biological process this GO :0004672 and protein kinase activity and molecular function this GO :0004713 and protein tyrosine kinase activity and molecular function this GO :0004714 and transmembrane receptor protein tyrosine kinase activity and molecular function this GO :0005003 and ephrin receptor activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005524 and ATP binding and molecular function this GO :0005886 and plasma membrane and cellular component this GO :0005887 and integral component of plasma membrane and cellular component this GO :0005925 and focal adhesion and cellular component this GO :0006468 and protein phosphorylation and biological process this GO :0007155 and cell adhesion and biological process this GO :0007169 and transmembrane receptor protein tyrosine kinase signaling pathway and biological process this GO :0007275 and multicellular organismal development and biological process this GO :0008630 and intrinsic apoptotic signaling pathway in response to DNA damage and biological process this GO :0010591 and regulation of lamellipodium assembly and biological process this GO :0014028 and notochord formation and biological process this GO :0016032 and viral process and biological process this GO :0016477 and cell migration and biological process this GO :0016772 and transferase activity, this GO :0004672: protein kinase activity, this GO :0004672: protein kinase activity and also this GO :0004713: protein tyrosine kinase activity and also this GO :0004714: transmembrane receptor protein tyrosine kinase activity and also this GO :0005003: ephrin receptor activity and also this GO :0005515: protein binding and also this GO :0005524: ATP binding and also this GO :0016772: transferase activity, this GO :0004713: protein tyrosine kinase activity, this GO :0004714: transmembrane receptor protein tyrosine kinase activity, this GO :0005003: ephrin receptor activity, this GO :0005515: protein binding, this GO :0005524: ATP binding, this GO :0016772: transferase activity, transferase activity, transferring phosphorus-containing groups, transferring phosphorus-containing groups, transferring phosphorus-containing groups and molecular function this GO :0018108 and peptidyl-tyrosine phosphorylation and biological process this GO :0021915 and neural tube development and biological process this GO :0030182 and neuron differentiation and biological process this GO :0030216 and keratinocyte differentiation and biological process this GO :0030316 and osteoclast differentiation and biological process this GO :0031256 and leading edge membrane and cellular component this GO :0031258 and lamellipodium membrane and cellular component this GO :0032587 and ruffle membrane and cellular component this GO :0032863 and activation of Rac GTPase activity and biological process this GO :0033598 and mammary gland epithelial cell proliferation and biological process this GO :0033628 and regulation of cell adhesion mediated by integrin and biological process this GO :0036342 and post-anal tail morphogenesis and biological process this GO :0043491 and protein kinase B signaling and biological process this GO :0043535 and regulation of blood vessel endothelial cell migration and biological process this GO :0045765 and regulation of angiogenesis and biological process this GO :0046849 and bone remodeling and biological process this GO :0048013 and ephrin receptor signaling pathway and biological process this GO :0048320 and axial mesoderm formation and biological process this GO :0048570 and notochord morphogenesis and biological process this GO :0051898 and negative regulation of protein kinase B signaling and biological process this GO :0060035 and notochord cell development and biological process this GO :0060326 and cell chemotaxis and biological process this GO :0060444 and branching involved in mammary gland duct morphogenesis and biological process this GO :0070309 and lens fiber cell morphogenesis and biological process this GO :0070372 and regulation of ERK1 and ERK2 cascade and biological process this GO :0070848 and response to growth factor and biological process this GO :0090004 and positive regulation of establishment of protein localization to plasma membrane and biological process, EPH receptor A2 |
| Identity | 3386 |
| Gene | EPHA2 |
| Long gene name | EPH receptor A2 |
| Synonyms gene | ECK |
| Synonyms gene name | EphA2 |
| Locus | 1p36, 13 |
| Discovery year | 1991-08-07 |
| GenBank acession | BC037166 |
| Entrez gene record | 1969 |
| Pubmed identfication | 9119409 |
| RefSeq identity | NM_004431 |
| Classification | Sterile alpha motif domain containing Fibronectin type III domain containing EPH receptors |
| Havana BLAST/BLAT | OTTHUMG00000009527 |
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