| Also known as | PP2Ac / PPP2CA |
| Other names | PP2A-alpha, RP-C, Replication protein C, Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform, alpha isoform, alpha isoform, alpha isoform, alpha isozyme, catalytic subunit, catalytic subunit, catalytic subunit, protein phosphatase 2, protein phosphatase 2 (formerly 2A), protein phosphatase 2A catalytic subunit, replication protein C, serine/threonine protein phosphatase 2A, serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform, serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform |
| Category | Antibodies |
| Subcategory | Mnoclonal antibodies |
| Gene name | PP2Ac |
| Gene name synonims | PPP2CA |
| Other gene names | PP2A-alpha, PP2Ac, PP2CA, PP2Calpha, PPP2CA, RP-C, RP-C, PPP2CA |
| Clonality | Monoclonal |
| Immunoglobulin isotype | IgG2b, k |
| Clone | P6C7 |
| Host organism | Mouse (Mus musculus) |
| Species reactivity | Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby, Human (Homo sapiens) |
| Specificity and cross-reactivity | Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited, This particular antibody might cross react with speacies outside of the listed ones, N/A |
| Purification method | Protein G Purified |
| Form/Appearance | 0, pH 7, 1% sodium azide, 4, PBS |
| Concentration | N/A |
| Storage and shipping | Cycles of freezing/defrosting can damage the peptide chains of the antibodies thus reducing the activity, Short term storage of the antibody can be done at +4 degrees Celsius, keep the antibody at -20 degrees Celsius, For long term storage |
| Tested applications: | ELISA (EIA), Immunoprecipitation (IP), Western Blot (WB), Immunohistochemistry (IHC - Paraffin) |
| Properties | Depending on the epitopes used human ELISA kits can be cross reactive to many other species, Human proteins, Mainly analyzed are human serum, Modern , cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies, human cell culture supernatants and biological samples, plasma, primarily , saliva, urine, , (Homo sapiens, C, C for long term storage and for short term at + 5°, Homo sapiens sapiens), If you buy Antibodies supplied by MBS mono they should be stored frozen at - 24°, humans , ssp |
| About | Each murine monoclonal anibody has his own affinity specific for the clone, Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes, Monoclonals of this antigen are available in different clones |
| Test | A/J, BALB/c, Mouse are mature after 40 days for females and 55 days for males, SCID while the CD-1 is outbred as strain, The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year, Transgenic, congenic and inbread strains are known for C57BL/6, knock-out, Mouse , mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab, or |
| Latin name | Mus musculus |
| Gene target | Monoclonal [ P6C7] (IgG2b, k) PP2Ac / PPP2CA |
| Short name | Mouse Monoclonal [clone P6C7] (IgG2b, k) PP2Ac / PPP2CA Antibody |
| Technique | Monoclonals or monoclonal antibodies, antibodies against human proteins, antibodies for, mouses, Antibody |
| Isotype | IgG2b |
| Species | Humans, Mouses, Human |
| Alternative name | a isozyme (Antibody to), catalytic subunit, sapiens PP2Ac / protein phosphatase 2, Mouse monoclonal [clonality P6C7] (IgG2b, k) to H |
| Alternative technique | antibodies |
| Alternative to gene target | DNA-templated and biological process this GO :0006470 and protein dephosphorylation and biological process this GO :0006672 and ceramide metabolic process and biological process this GO :0006915 and apoptotic process and biological process this GO :0007084 and mitotic nuclear envelope reassembly and biological process this GO :0007126 and meiotic nuclear division and biological process this GO :0007498 and mesoderm development and biological process this GO :0008022 and protein C-terminus binding and molecular function this GO :0008380 and RNA splicing and biological process this GO :0008543 and fibroblast growth factor receptor signaling pathway and biological process this GO :0010033 and response to organic substance and biological process this GO :0010467 and gene expression and biological process this GO :0010469 and regulation of receptor activity and biological process this GO :0010719 and negative regulation of epithelial to mesenchymal transition and biological process this GO :0015630 and microtubule cytoskeleton and cellular component this GO :0016020 and membrane and cellular component this GO :0016070 and RNA metabolic process and biological process this GO :0016071 and mRNA metabolic process and biological process this GO :0016311 and dephosphorylation and biological process this GO :0016787 and hydrolase activity and molecular function this GO :0019932 and second-messenger-mediated signaling and biological process this GO :0030111 and regulation of Wnt signaling pathway and biological process this GO :0030155 and regulation of cell adhesion and biological process this GO :0030308 and negative regulation of cell growth and biological process this GO :0031952 and regulation of protein autophosphorylation and biological process this GO :0040008 and regulation of growth and biological process this GO :0042176 and regulation of protein catabolic process and biological process this GO :0042518 and negative regulation of tyrosine phosphorylation of Stat3 protein and biological process this GO :0045595 and regulation of cell differentiation and biological process this GO :0046872 and metal ion binding and molecular function this GO :0046983 and protein dimerization activity and molecular function this GO :0050811 and GABA receptor binding and molecular function this GO :0070062 and extracellular vesicular exosome and cellular component this GO :0070208 and protein heterotrimerization and biological process this GO :0071902 and positive regulation of protein serine/threonine kinase activity and biological process, GABA receptor binding, PP2Ac and PP2CA and PP2Calpha and RP-C, PPP2CA and IDBG-44693 and ENSG00000113575 and 5515, PPP2CA and IDBG-645797 and ENSBTAG00000000469 and 282320, Ppp2ca and IDBG-170858 and ENSMUSG00000020349 and 19052, alpha isozyme, catalytic subunit, centromeric region and cellular component this GO :0000922 and spindle pole and cellular component this GO :0001932 and regulation of protein phosphorylation and biological process this GO :0004721 and phosphoprotein phosphatase activity and molecular function this GO :0004722 and protein serine/threonine phosphatase activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0005739 and mitochondrion and cellular component this GO :0005829 and cytosol and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0006275 and regulation of DNA replication and biological process this GO :0006355 and regulation of transcription, nonsense-mediated decay and biological process this GO :0000188 and inactivation of MAPK activity and biological process this GO :0000278 and mitotic cell cycle and biological process this GO :0000775 and chromosome, nuclei, this GO :0000159 and protein phosphatase type 2A complex and cellular component this GO :0000184 and nuclear-transcribed mRNA catabolic process, this GO :0004721: phosphoprotein phosphatase activity, this GO :0004721: phosphoprotein phosphatase activity and also this GO :0004722: protein serine/threonine phosphatase activity and also this GO :0005515: protein binding and also this GO :0008022: protein C-terminus binding and also this GO :0016787: hydrolase activity and also this GO :0046872: metal ion binding and also this GO :0046983: protein dimerization activity and also this GO :0050811: GABA receptor binding, this GO :0004722: protein serine/threonine phosphatase activity, this GO :0005515: protein binding, this GO :0008022: protein C-terminus binding, this GO :0016787: hydrolase activity, this GO :0046872: metal ion binding, this GO :0046983: protein dimerization activity, this GO :0050811: GABA receptor binding, protein phosphatase 2 |
| Identity | 9299 |
| Gene | PPP2CA |
| Long gene name | protein phosphatase 2 catalytic subunit alpha |
| Synonyms gene name | alpha isoform protein phosphatase 2, alpha isozyme , catalytic subunit, catalytic subunit, protein phosphatase 2 (formerly 2A) |
| Synonyms | PP2Calpha PP2AC |
| Synonyms name | alpha isoform , protein phosphatase 2A catalytic subunit |
| Locus | 5q31, 1 |
| Discovery year | 1992-11-10 |
| Entrez gene record | 5515 |
| Pubmed identfication | 8383590 |
| RefSeq identity | NM_002715 |
| Classification | STRIPAK complex Protein phosphatase catalytic subunits |
| Havana BLAST/BLAT | OTTHUMG00000129119 |
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