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Mouse monoclonal MLH1 antibody

Mouse monoclonal MLH1 antibody size: 100ul 420

Supplier MBS MONO
Price 420
Size 100ul
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Also known asMLH1
Other names DNA mismatch repair protein Mlh1, DNA mismatch repair protein Mlh1, MutL protein homolog 1, colon cancer, mutL homolog 1, mutL homolog 1, nonpolyposis type 2, DNA mismatch repair protein Mlh1 isoform 1
CategoryAntibodies
SubcategoryMnoclonal antibodies
Gene nameMLH1
Gene name synonims COCA2, HNPCC, HNPCC2, hMLH1, FCC2
Other gene names COCA2, COCA2, FCC2, HNPCC, HNPCC2, MLH1, hMLH1, MLH1
ClonalityMonoclonal
Immunoglobulin isotypeIgG2b
Clone2B3-H6-C11
Host organismMouse (Mus musculus)
Source organismHuman (Homo sapiens)
Species reactivity Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby, Human (Homo sapiens)
Specificity and cross-reactivity Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited, This particular antibody might cross react with speacies outside of the listed ones, This antibody detects endogenous levels of MLH1 and does not cross-react with related proteins
Purification methodAffinity purified
Form/Appearance Purified mouse monoclonal in PBS(pH 7, 02% sodium azide, 1mg/mlBSA and 50% glycerol, 4) containing with 0, Liquid
Concentration1 miligram per 1 mililiter
Storage and shipping Cycles of freezing and thawing may denaturate the polypeptide chains of the antibodies and reduce their activity and should be avoided, the antibody should be aliquoted and kept at -20 degrees Celsius, For optimal long term storage
Tested applications:Western Blot (WB)
Test A/J, BALB/c, Mouse are mature after 40 days for females and 55 days for males, SCID while the CD-1 is outbred as strain, The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year, Transgenic, congenic and inbread strains are known for C57BL/6, knock-out, Mouse , mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab, or 
Latin nameMus musculus
French translationanticorps
Gene targetmonoclonal MLH1
Short nameMouse monoclonal MLH1 antibody
Technique mouse monoclonals, mouses, Mouse monoclonal
HostMurine monoclonal antibodies or Mabs are often conjugated and the isotype is IgG
Species Mouses, Mouse
Alternative name coli) (Antibody to), colon cancer, nonpolyposis classification 2 (E, Mouse monoclonal mutL homolog 1
Alternative techniquemurine
Alternative to gene target COCA2 and FCC2 and hMLH1 and HNPCC and HNPCC2, MLH1 and IDBG-24600 and ENSG00000076242 and 4292, MLH1 and IDBG-644253 and ENSBTAG00000016758 and 533652, Mlh1 and IDBG-202755 and ENSMUSG00000032498 and 17350, coli), colon cancer, nonpolyposis type 2 (E, nuclei, structure-specific DNA binding, this GO :0000289 and nuclear-transcribed mRNA poly(A) tail shortening and biological process this GO :0000712 and resolution of meiotic recombination intermediates and biological process this GO :0000793 and condensed chromosome and cellular component this GO :0000794 and condensed nuclear chromosome and cellular component this GO :0000795 and synaptonemal complex and cellular component this GO :0001673 and male germ cell nucleus and cellular component this GO :0002204 and somatic recombination of immunoglobulin genes involved in immune response and biological process this GO :0003697 and single-stranded DNA binding and molecular function this GO :0005515 and protein binding and molecular function this GO :0005524 and ATP binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0005694 and chromosome and cellular component this GO :0005712 and chiasma and cellular component this GO :0006200 and ATP catabolic process and biological process this GO :0006281 and DNA repair and biological process this GO :0006298 and mismatch repair and biological process this GO :0006303 and double-strand break repair via nonhomolo this GO us end joining and biological process this GO :0006974 and cellular response to DNA damage stimulus and biological process this GO :0007060 and male meiosis chromosome segregation and biological process this GO :0007129 and synapsis and biological process this GO :0007131 and reciprocal meiotic recombination and biological process this GO :0007140 and male meiosis and biological process this GO :0007283 and spermatogenesis and biological process this GO :0008630 and intrinsic apoptotic signaling pathway in response to DNA damage and biological process this GO :0016020 and membrane and cellular component this GO :0016446 and somatic hypermutation of immunoglobulin genes and biological process this GO :0016447 and somatic recombination of immunoglobulin gene segments and biological process this GO :0016887 and ATPase activity and molecular function this GO :0030983 and mismatched DNA binding and molecular function this GO :0032137 and guanine/thymine mispair binding and molecular function this GO :0032300 and mismatch repair complex and cellular component this GO :0032389 and MutLalpha complex and cellular component this GO :0032407 and MutSalpha complex binding and molecular function this GO :0043060 and meiotic metaphase I plate congression and biological process this GO :0043566 and structure-specific DNA binding and molecular function this GO :0045132 and meiotic chromosome segregation and biological process this GO :0045190 and isotype switching and biological process this GO :0045950 and negative regulation of mitotic recombination and biological process this GO :0048477 and oogenesis and biological process this GO :0051257 and spindle midzone assembly involved in meiosis and biological process, this GO :0003697: single-stranded DNA binding, this GO :0003697: single-stranded DNA binding and also this GO :0005515: protein binding and also this GO :0005524: ATP binding and also this GO :0016887: ATPase activity and also this GO :0030983: mismatched DNA binding and also this GO :0032137: guanine/thymine mispair binding and also this GO :0032407: MutSalpha complex binding and also this GO :0043566: structure-specific DNA binding, this GO :0005515: protein binding, this GO :0005524: ATP binding, this GO :0016887: ATPase activity, this GO :0030983: mismatched DNA binding, this GO :0032137: guanine/thymine mispair binding, this GO :0032407: MutSalpha complex binding, this GO :0043566: structure-specific DNA binding, mutL homolog 1
Identity 7127
Gene MLH1
Long gene name mutL homolog 1
Synonyms gene COCA2
Synonyms gene name coli) , coli) homolog 1 (colon cancer, colon cancer, mutL (E, nonpolyposis type 2 (E, nonpolyposis type 2) mutL homolog 1
Synonyms HNPCC FCC2 HNPCC2
Locus 3p22, 2
Discovery year 1993-11-24
GenBank acession U07418
Entrez gene record 4292
Pubmed identfication 7903889
RefSeq identity NM_000249
Classification MutL homologs
Havana BLAST/BLAT OTTHUMG00000130797
Locus Specific Databases HNPCC Colon cancer gene variant databases MLH1 database at LOVD-China LOVD - Leiden Open Variation Database LRG_216 , Hereditary Non-Polyposis Colorectal Cancer

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