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MPO Antibody Myeloperoxidase

MPO Antibody Myeloperoxidase size: 0.1mg 406

Supplier NJS POLY
Price 406
Size 0.1mg
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
CategoryAntibody
Concentration2ml sterile DI water, 5mg/ml if reconstituted with 0
FormAntigen affinity purified
ConjugationUnconjugated
ClonePolyclonal antibody
Recognised antigenMPO Myeloperoxidase
Host animalRabbit (Oryctolagus cuniculus)
ClonalityPolyclonal (rabbit origin)
Species reactivity Due to limited knowledge and inability to test the antibody against all known species, Mouse (Mus musculus), Rat , we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens)
Tested applications IHC-P, WB
Recommended dilutions5-1ug/ml, 5-1ug/ml, IHC (Paraffin): 0, Western blot: 0
Notes Titration of the MPO antibody may be required due to differences in protocols and secondary/substrate sensitivity, The stated application concentrations are suggested starting points
Intented useThis MPO antibodyis to be used only for research purposes and not for diagnostics
Gene ID #4353
PurityAntigen affinity
Description It is abundantly expressed in neutrophils and secreted during their activation, Located in the nucleus as well as in the cytoplasm, MPO is part of the host defense system of human polymorphonuclear leukocytes, intranuclear MPO may help to protect DNA against damage resulting from oxygen radicals produced during myeloid cell maturation and function, responsible for microbicidal activity against a wide range of organisms, Myeloperoxidase is a mammalian phagocyte hemoprotein thought to primarily mediate host defense reactions
ImmunogenHuman partial recombinant protein (AA 406-745) was used as the immunogen for this MPO antibody
Storage Avoid repeated freezing and thawing, Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, For long-term, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, aliquot and store at -20 deg, the MPO antibody can be stored for up to one month at 4oC, After reconstitution
LocalizationNuclear and cytoplasmic
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°
Gene targetMPO Myeloperoxidase
Short nameMPO Antibody Myeloperoxidase
Technique antibodies against human proteins, antibodies for, Antibody
Alternative namemyeloperoxidase (Antibody to) Myeloperoxidase
Alternative techniqueantibodies
Alternative to gene target MPO and IDBG-60932 and ENSG00000005381 and 4353, MPO and IDBG-629390 and ENSBTAG00000011616 and 511206, Mpo and IDBG-207719 and ENSMUSG00000009350 and 17523, metal ion binding, nuclei, this GO :0001878 and response to yeast and biological process this GO :0002149 and hypochlorous acid biosynthetic process and biological process this GO :0002679 and respiratory burst involved in defense response and biological process this GO :0003682 and chromatin binding and molecular function this GO :0004601 and peroxidase activity and molecular function this GO :0005615 and extracellular space and cellular component this GO :0005634 and nucleus and cellular component this GO :0005739 and mitochondrion and cellular component this GO :0005764 and lysosome and cellular component this GO :0006952 and defense response and biological process this GO :0006979 and response to oxidative stress and biological process this GO :0007568 and aging and biological process this GO :0008201 and heparin binding and molecular function this GO :0009612 and response to mechanical stimulus and biological process this GO :0019430 and removal of superoxide radicals and biological process this GO :0020037 and heme binding and molecular function this GO :0030141 and secretory granule and cellular component this GO :0032094 and response to food and biological process this GO :0032496 and response to lipopolysaccharide and biological process this GO :0034374 and low-density lipoprotein particle remodeling and biological process this GO :0042582 and azurophil granule and cellular component this GO :0042744 and hydrogen peroxide catabolic process and biological process this GO :0043066 and negative regulation of apoptotic process and biological process this GO :0044130 and negative regulation of growth of symbiont in host and biological process this GO :0046872 and metal ion binding and molecular function this GO :0050832 and defense response to fungus and biological process this GO :0055114 and oxidation-reduction process and biological process this GO :0070062 and extracellular vesicular exosome and cellular component this GO :1990268 and response to this GO ld nanoparticle and biological process, this GO :0003682: chromatin binding, this GO :0003682: chromatin binding and also this GO :0004601: peroxidase activity and also this GO :0008201: heparin binding and also this GO :0020037: heme binding and also this GO :0046872: metal ion binding, this GO :0004601: peroxidase activity, this GO :0008201: heparin binding, this GO :0020037: heme binding, this GO :0046872: metal ion binding, myeloperoxidase
Identity 7218
Gene MPO
Long gene name myeloperoxidase
Locus 17q22
Discovery year 2001-06-22
Entrez gene record 4353
Havana BLAST/BLAT OTTHUMG00000178922
Locus Specific Databases MPObase: Mutation registry for Myeloperoxidase deficiency LRG_84

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