Name : MPP5/PALS1 Antibody
Supplier : BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price :263
SKU : GEN9069484394
| Long name | MPP5/PALS1 Primary Polyclonal Antibody |
| Also known as | MPP5/PALS1 PAb |
| Category | Primary Antibodies |
| Conjugation | Unconjugated |
| Target Antigen | MPP5/PALS1 |
| Specificity | This is a highly specific antibody against MPP5/PALS1 |
| Modification(s) | None |
| Modification site(s) | Unmodified antibody |
| Clonality | Polyclonal antibody |
| Clone number | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Source | This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human MPP5/PALS1 |
| Tested Applications | IF(IHC-P), IHC-P, WB |
| Recommended dilutions | IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity | Mouse, Rat, Human |
| Cross reactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen | Because tumors exhibit perturbations in epithelial polarity, Loss of Pals1 function results in delayed polarization, Pals1, Pals1 presents a new potential target in the study of carcinogenesis, Tight junctions assist in the formation of polarity in the epithelia by establishing a barrier to separate apical and basolateral membranes, decreased transepithelial electrical resistance and an inability to form lumenal cysts, importantly, mediates interaction between the two complexes via interaction with Par6, the Crumbs-Pals1-Patj complex and the Cdc42-Par6-Par3-aPKC complex, Two highly conserved complexes are responsible for the assembly of tight junctions |
| Purification method | This antibody was purified via Protein A |
| Storage conditions | 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names | MAGUK p55 subfamily member 5, MPP 5, MPP5, MPP5_HUMAN, Membrane protein palmitoylated 5, PALS 1, PALS1, Protein associated with Lin-7, Stardust, Stardust Drosophila, FLJ12615 |
| Properties | C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target | MPP5/PALS1 |
| Short name | MPP5/PALS1 Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Alternative name | MPP5/PALS1 (Antibody to) |
| Alternative technique | antibodies |
| Identity | 18669 |
| Gene | MPP5 |
| Long gene name | membrane palmitoylated protein 5 |
| Synonyms gene name | membrane protein, palmitoylated 5 , palmitoylated 5 (MAGUK p55 subfamily member 5) membrane protein |
| Synonyms | PALS1 FLJ12615 |
| Synonyms name | stardust protein associated with Lin-7 1 |
| Locus | 14q23, 3 |
| Discovery year | 2002-05-23 |
| GenBank acession | AK022677 |
| Entrez gene record | 64398 |
| Pubmed identfication | 11927608 |
| RefSeq identity | NM_022474 |
| Classification | Crumbs complex Membrane associated guanylate kinases PDZ domain containing |
| Havana BLAST/BLAT | OTTHUMG00000171243 |