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MRC2 Antibody

MRC2 Antibody size: 0.1ml 263

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price 263
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long nameMRC2 Primary Polyclonal Antibody
Also known asMRC2 PAb
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenMRC2
SpecificityThis is a highly specific antibody against MRC2
Modification(s)None
Modification site(s)Unmodified antibody
ClonalityPolyclonal antibody
Clone numberPolyclonal antibody
Concentration1ug per 1ul
Immunogen range370-420/1479
Subcellular locationExtracellular
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human MRC2/CD280
Gene ID number9902
Swiss ProtQ9UBG0
Tested Applications IF(IHC-P), IHC-P, WB
Recommended dilutions IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000)
Cross reactivity Mouse, Rat, Human
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen Internalizes glycosylated ligands from the extracellular space for release in an endosomal compartment via clathrin-mediated endocytosis, May be involved in plasminogen activation system controlling the extracellular level of PLAUR/PLAU, May contribute to cellular uptake, May participate in remodeling of extracellular matrix cooperating with the matrix metalloproteinases (MMPs), May play a role during cancer progression as well as in other chronic tissue destructive diseases acting on collagen turnover, and thus may regulate protease activity at the cell surface, remodeling and degradation of extracellular collagen matrices, May play a role as endocytotic lectin receptor displaying calcium-dependent lectin activity
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names C-type lectin domain family 13 member E, C-type mannose receptor 2, CLEC13E, ENDO180, Endocytic receptor 180, KIAA0709, MRC2, Macrophage mannose receptor 2, UPAR-associated protein, UPARAP, Urokinase receptor-associated protein, Urokinase-type plasminogen activator receptor-associated protein, CD280
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene targetMRC2
Short nameMRC2 Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative name C type 2 (Antibody to), mannose receptor
Alternative techniqueantibodies
Alternative to gene target C type 2, CD280 and CLEC13E and ENDO180 and UPARAP, MRC2 and IDBG-63031 and ENSG00000011028 and 9902, MRC2 and IDBG-641433 and ENSBTAG00000015739 and 529049, Mrc2 and IDBG-213230 and ENSMUSG00000020695 and 17534, Plasma membranes, carbohydrate binding, this GO :0001649 and osteoblast differentiation and biological process this GO :0005515 and protein binding and molecular function this GO :0005518 and collagen binding and molecular function this GO :0006897 and endocytosis and biological process this GO :0016020 and membrane and cellular component this GO :0016021 and integral component of membrane and cellular component this GO :0030246 and carbohydrate binding and molecular function this GO :0030574 and collagen catabolic process and biological process, this GO :0005515: protein binding, this GO :0005515: protein binding and also this GO :0005518: collagen binding and also this GO :0030246: carbohydrate binding, this GO :0005518: collagen binding, this GO :0030246: carbohydrate binding, mannose receptor
Identity 16875
Gene MRC2
Long gene name mannose receptor C type 2
Synonyms gene name C type 2 , mannose receptor
Synonyms KIAA0709 ENDO180 CLEC13E CD280
Synonyms name C-type lectin domain family 13 member E endocytic receptor 180
Locus 17q23
Discovery year 2002-09-24
GenBank acession AB014609
Entrez gene record 9902
Pubmed identfication 9734811 8702911
Classification CD molecules C-type lectin domain family
Havana BLAST/BLAT OTTHUMG00000179178

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