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MRE11 (44B12) Monoclonal Antibody

MRE11 (44B12) Monoclonal Antibody size: 0.1ml 362

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price 362
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long nameMRE11 (44B12) Monoclonal Antibody
Also known asMRE11 (44B12) Monoclonal Antibody
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenMRE11
SpecificityThis is a highly specific antibody against MRE11
Modification(s)None
Modification site(s)Unmodified antibody
ClonalityMonoclonal
Clone number44B12
Concentration1ug per 1ul
SourceRecombinant human protein purified from E, coli (His-MRE11)
Gene ID number4361
Swiss ProtP49959
Tested Applications IP, WB
Recommended dilutions0 ug), 2 ug/mL) IP (2, WB (0
Cross reactivityHuman
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen DNA recombination, In telomeres the MRN complex may modulate t-loop formation (PubMed:10888888), PubMed:11741547), PubMed:9590181, PubMed:9705271, RAD50 may be required to bind DNA ends and hold them in close proximity, The complex may also be required for DNA damage signaling via activation of the ATM kinase (PubMed:15064416), The complex possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity, This could facilitate searches for short or long regions of sequence homology in the recombining DNA templates, and may also stimulate the activity of DNA ligases and/or restrict the nuclease activity of MRE11A to prevent nucleolytic degradation past a given point (PubMed:9651580, maintenance of telomere integrity and meiosis, which are provided by MRE11A, which plays a central role in double-strand break (DSB) repair, Component of the MRN complex
Purification methodPurified by Protein G
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names Double-strand break repair protein MRE11A, HNGS1, MRE11, MRE11 homolog 1, MRE11 homolog A, MRE11A, MRE11B, Meiotic recombination 11 homolog 1, Meiotic recombination 11 homolog A, ATLD
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
About Each murine monoclonal anibody has his own affinity specific for the clone, Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes, Monoclonals of this antigen are available in different clones
Gene targetMRE11 (44B12) Monoclonal
Short nameMRE11 (44B12) Monoclonal Antibody
Technique Monoclonals or monoclonal antibodies, antibodies against human proteins, antibodies for, Antibody
Alternative nameMRE11 (44B12) monoclonal (Antibody to)
Alternative techniqueantibodies
Identity 7230
Gene MRE11
Long gene name MRE11 homolog, double strand break repair nuclease
Synonyms gene MRE11A
Synonyms gene name MRE11 meiotic recombination 11 homolog A (S, cerevisiae) MRE11 homolog A, double strand break repair nuclease
Synonyms ATLD
Synonyms name AT-like disease
Locus 11q21
Discovery year 1995-05-05
GenBank acession BC063458
Entrez gene record 4361
Pubmed identfication 8530104 24316220
RefSeq identity NM_005591
Classification BRCA1 C complex MRN complex
Havana BLAST/BLAT OTTHUMG00000167780
Locus Specific Databases MRE11Abase: Mutation registry for Ataxia-telangiectasia-like disorder (ATLD) LRG_85

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