Name : Mre11 Antibody, Cy7 Conjugated
Supplier : BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price :350
SKU : GEN1668429804
| Long name | Cy7 Conjugated, Mre11 Polyclonal Antibody |
| Category | Conjugated Primary Antibodies |
| Conjugation | Cy7 |
| Host Organism | Rabbit (Oryctolagus cuniculus) |
| Target Antigen | Mre11 |
| Specificity | This is a highly specific antibody against Mre11 |
| Modification | Unmodified |
| Modification site | None |
| Clonality | Polyclonal |
| Clone | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Immunogen_range | 450-490/708 |
| Subcellular location | Nucleus |
| Source | KLH conjugated synthetic peptide derived from human Mre11/HNGS1 |
| Gene ID number | 4361 |
| Swiss Prot | P49959 |
| Tested applications | IF(IHC-P) |
| Recommended dilutions | IF(IHC-P)(1:50-200) |
| Crossreactivity | Mouse, Rat, Human |
| Crossreactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background | DNA recombination, In telomeres the MRN complex may modulate t-loop formation, RAD50 may be required to bind DNA ends and hold them in close proximity, The complex may also be required for DNA damage signaling via activation of the ATM kinase, The complex possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity, This could facilitate searches for short or long regions of sequence homology in the recombining DNA templates, and may also stimulate the activity of DNA ligases and/or restrict the nuclease activity of MRE11A to prevent nucleolytic degradation past a given point, maintenance of telomere integrity and meiosis, which are provided by MRE11A, which plays a central role in double-strand break (DSB) repair, Component of the MRN complex |
| Purification method | This antibody was purified via Protein A |
| Storage conditions | 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission | 743nm/767nm |
| Synonyms | Double-strand break repair protein MRE11A, HNGS1, MRE11, MRE11 homolog 1, MRE11 homolog A, MRE11A, MRE11B, Meiotic recombination 11 homolog 1, Meiotic recombination 11 homolog A, ATLD |
| Properties | C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Conjugated | These antibodies are excite for emission at 650 nm and detected at a 676 nm wavelengths |
| Gene target | Mre11 Conjugated |
| Short name | Conjugated, Mre11 Antibody |
| Technique | antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label | Cy7 |
| Alternative name | cyanine 7 coupled, Mre11 (Antibody to) |
| Alternative technique | antibodies |