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MRGPRX1/3/4 Antibody, ALEXA FLUOR 488

MRGPRX1/3/4 Antibody, ALEXA FLUOR 488 size: 100ul 332

Supplier BIOSS PRIMARY CONJUGATED ANTIBODIES
Price 332
Size 100ul
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long name ALEXA FLUOR 488 Conjugated, MRGPRX1/3/4 Polyclonal Antibody
Also known asAnti-MRGPRX1/3/4 PAb ALEXA FLUOR 488
CategoryConjugated Primary Antibodies
Conjugated with 488, ALEXA FLUOR®
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenMRGPRX1/3/4
SpecificityThis is a highly specific antibody against MRGPRX1/3/4
ModificationUnmodified
Modification SiteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
Immunogen range1-35/322
Subcellular locationExtracellular
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human MRGX1
Gene ID Number 117195, 117196, 259249
Tested applicationsIF(IHC-P)
Recommended dilutionsIF(IHC-P)(1:50-200)
CrossreactivityHuman
Cross-reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the antigen BAM22 is the most potent compound and evoked a large and dose-dependent release of intracellular calcium in stably transfected cells, G Alpha q proteins are involved in the calcium-signaling pathway downstream of the MRGX receptors, G(alpha)q proteins are involved in the calcium-signaling pathway, MRGX receptors are unique in that they are expressed in a subset of small dorsal root and trigeminal sensory neurons, MRGX1 and MRGX2 receptors stimulate both G Alpha q- and G Alpha i -regulated pathways, May regulate nociceptor function and/or development, Potently activated by enkephalins including BAM22 (bovine adrenal medulla peptide 22) and BAM (8-22), Probably involved in the function of nociceptive neurons, including the sensation or modulation of pain, while MRGX3 and MRGX4 receptors mainly activate G Alpha q-regulated pathways, There are four members (MRGX1-4) in the human MRGX familly
PurificationPurified by Protein A
Storage conditions 50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA
Excitation emission499nm/519nm
Synonyms MRGX1
Properties ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 488 has the same range to that of fluorescein isothiocyanate (FITC), Also Alexa Fluor 488 is pH stable, As a result of this photo stability, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, It is distinguished in the FL1 of a FACS-Calibur or FACScan, has a very high photo stability, it has turned into an antibody for fluorescent microscopy and FACS FLOW cytometry, yet the MRGPRX1/3/4 Antibody, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate
ConjugationAlexa Fluor
Gene targetMRGPRX1/3/4
Short nameMRGPRX1/3/4 Antibody
Technique antibodies against human proteins, antibodies for, Antibody
LabelALEXA FLUOR 488
Alternative name ALEXA FLUOR 488, member X1/3/4 (Antibody to), MAS-related GPR
Alternative techniqueantibodies
Alternative to gene target G-protein coupled receptor activity, MRGPRX1 and IDBG-35377 and ENSG00000170255 and 259249, Plasma membranes, member X1, this GO :0004930 and G-protein coupled receptor activity and molecular function this GO :0005886 and plasma membrane and cellular component this GO :0006953 and acute-phase response and biological process this GO :0007186 and G-protein coupled receptor signaling pathway and biological process this GO :0016021 and integral component of membrane and cellular component, this GO :0004930: G-protein coupled receptor activity, this GO :0004930: G-protein coupled receptor activity, MAS-related GPR
Identity 17962
Gene MRGPRX1
Long gene name MAS related GPR family member X1
Synonyms gene name MAS-related GPR, member X1
Locus 11p15, 1
Discovery year 2005-05-09
Entrez gene record 259249
Pubmed identfication 11551509
RefSeq identity NM_147199
Classification Class A orphans , G protein-coupled receptors
Havana BLAST/BLAT OTTHUMG00000162655

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