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MRGPRX1/3/4 Antibody, Cy3 Conjugated

MRGPRX1/3/4 Antibody, Cy3 Conjugated size: 0.1ml 350

Supplier BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price 350
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long name Cy3 Conjugated, MRGPRX1/3/4 Polyclonal Antibody
CategoryConjugated Primary Antibodies
Conjugationcy3 conjugation kit
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenMRGPRX1/3/4
Specificity This may preferentially target MRGPRX1 over 3 and 4 due to slightly higher sequence similarity, This is a highly specific antibody against MRGPRX1/3/4
ModificationUnmodified
Modification siteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
Immunogen_range1-35/322
Subcellular locationExtracellular
SourceKLH conjugated synthetic peptide derived from human MRGX1
Gene ID number 117195, 117196, 259249
Tested applicationsIF(IHC-P)
Recommended dilutionsIF(IHC-P)(1:50-200)
CrossreactivityHuman
Crossreactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background BAM22 is the most potent compound and evoked a large and dose-dependent release of intracellular calcium in stably transfected cells, G Alpha q proteins are involved in the calcium-signaling pathway downstream of the MRGX receptors, G(alpha)q proteins are involved in the calcium-signaling pathway, MRGX receptors are unique in that they are expressed in a subset of small dorsal root and trigeminal sensory neurons, MRGX1 and MRGX2 receptors stimulate both G Alpha q- and G Alpha i -regulated pathways, May regulate nociceptor function and/or development, Potently activated by enkephalins including BAM22 (bovine adrenal medulla peptide 22) and BAM (8-22), Probably involved in the function of nociceptive neurons, including the sensation or modulation of pain, while MRGX3 and MRGX4 receptors mainly activate G Alpha q-regulated pathways, There are four members (MRGX1-4) in the human MRGX familly
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation Emission512, 550nm/570, 615nm
Synonyms MRGX1
Properties 1 of the MRGPRX1/3/4 Antibody, Conjugated can be used in flow cytometry but typically shows lower fluorescence intensity comparable to that of PE or APC, Cy3 antibodies are excited by the 488-nanometer wave of an argon laser and the 633-nanometer line of a helium-neon diode laser, This Bioss Primary Conjugated Antibodies antibody is well suited for fluorescent microscopy, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Gene targetMRGPRX1/3/4 Conjugated
Short name Conjugated, MRGPRX1/3/4 Antibody
Technique antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
LabelCy3
Alternative name cyanine 3 coupled, member X1/3/4 (Antibody to), MAS-related GPR
Alternative techniqueantibodies
Alternative to gene target G-protein coupled receptor activity, MRGPRX1 and IDBG-35377 and ENSG00000170255 and 259249, Plasma membranes, member X1, this GO :0004930 and G-protein coupled receptor activity and molecular function this GO :0005886 and plasma membrane and cellular component this GO :0006953 and acute-phase response and biological process this GO :0007186 and G-protein coupled receptor signaling pathway and biological process this GO :0016021 and integral component of membrane and cellular component, this GO :0004930: G-protein coupled receptor activity, this GO :0004930: G-protein coupled receptor activity, MAS-related GPR
Identity 17962
Gene MRGPRX1
Long gene name MAS related GPR family member X1
Synonyms gene name MAS-related GPR, member X1
Locus 11p15, 1
Discovery year 2005-05-09
Entrez gene record 259249
Pubmed identfication 11551509
RefSeq identity NM_147199
Classification Class A orphans , G protein-coupled receptors
Havana BLAST/BLAT OTTHUMG00000162655

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