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MSK1 (Ser212) Antibody

MSK1 (Ser212) Antibody size: 0.1ml 281

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price 281
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long nameMSK1 (Ser212) Primary Polyclonal Antibody
Also known asMSK1 (Ser212) PAb
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenMSK1 Ser212
SpecificityThis is a highly specific antibody against MSK1 Ser212
Modification(s)Phosphorylation
Modification site(s)Ser212
ClonalityPolyclonal antibody
Clone numberPolyclonal antibody
Concentration1ug per 1ul
SourceKLH conjugated synthetic phosphopeptide derived from human MSK1 around the phosphorylation site of Ser212 [AY(p-S)FC]
Gene ID number9252
Tested Applications IF(IHC-P), IHC-P, WB
Recommended dilutions IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000)
Cross reactivity Mouse, Rat, Human
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen ATF1 H3 and HMG14 in response to mitogen and stress, It is also known to be required for the phosphorylation of CREB, MSK1 autophosphorylate on at least 5 sites, MSK1 can be activated by ERK1/2 and SAPK2/p38 MAP kinase, MSK1 contains two kinase domains (N term and a C term), Of these autophosphorylation sites Ser212 and Ser376 get phosphorylated by the C terminal kinase domain of MSK1 which is essential for the catalytic activity of the N terminal kinase domain, Once phosphorylated on Thr581 and Ser360 by ERK1/2 and SAPK2/p38, Similar to RSK, MSK1 is a mitogen and stress activated protein kinase 1 which belongs to the AGC family of kinases and is related in structure to the ribosomal p70 S6 kinase subfamily
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names 90 kDa ribosomal protein S6 kinase 5, EC 2, KS6A5_HUMAN, MGC1911, MSPK1, Mitogen and stress activated protein kinase 1, Nuclear Mitogen And Stress Activated Protein Kinase 1, Nuclear mitogen- and stress-activated protein kinase 1, RLPK, RPS6KA5, RSK Like Protein Kinase, RSK-like protein kinase, RSKL, Ribosomal Protein S6 Kinase Alpha 5, Ribosomal protein S6 kinase 90kD polypeptide 5, Ribosomal protein S6 kinase 90kDa, Ribosomal protein S6 kinase 90kDa polypeptide 5, Ribosomal protein S6 kinase alpha-5, S6K alpha 5, S6K-alpha-5, 1, 7, 11, MSK1 Phospho Ser212
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene targetMSK1 (Ser212)
Short nameMSK1 (Ser212) Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameMSK1 (Ser212) (Antibody to)
Alternative techniqueantibodies
Identity 10434
Gene RPS6KA5
Long gene name ribosomal protein S6 kinase A5
Synonyms gene name 90kD, polypeptide 5 , ribosomal protein S6 kinase
Synonyms MSK1 RLPK
Locus 14q32, 11
Discovery year 1999-03-10
GenBank acession AF074393
Entrez gene record 9252
Pubmed identfication 9687510 10702687
RefSeq identity NM_004755
Classification Mitogen-activated protein kinase-activated protein kinases
Havana BLAST/BLAT OTTHUMG00000171055

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