Name : MSK1 (Thr581) Antibody, ALEXA FLUOR 594
Supplier : BIOSS PRIMARY CONJUGATED ANTIBODIES
Price :350
SKU : GEN4053420387
| Long name | ALEXA FLUOR 594 Conjugated, MSK1 (Thr581) Polyclonal Antibody |
| Also known as | Anti-MSK1 Thr581 PAb ALEXA FLUOR 594 |
| Category | Conjugated Primary Antibodies |
| Conjugated with | 594, ALEXA FLUOR® |
| Host Organism | Rabbit (Oryctolagus cuniculus) |
| Target Antigen | MSK1 Thr581 |
| Specificity | This is a highly specific antibody against MSK1 Thr581 |
| Modification | Phosphorylation |
| Modification Site | Thr581 |
| Clonality | Polyclonal |
| Clone | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Source | KLH conjugated synthetic phosphopeptide derived from human MSK1 around the phosphorylation site of Thr581 [LK(p-T)PC] |
| Gene ID Number | 9252 |
| Tested applications | IF(IHC-P) |
| Recommended dilutions | IF(IHC-P)(1:50-200) |
| Crossreactivity | Mouse, Human |
| Cross-reactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen | ATF1 H3 and HMG14 in response to mitogen and stress, It is also known to be required for the phosphorylation of CREB, MSK1 autophosphorylate on at least 5 sites, MSK1 can be activated by ERK1/2 and SAPK2/p38 MAP kinase, MSK1 contains two kinase domains (N term and a C term), Of these autophosphorylation sites Ser212 and Ser376 get phosphorylated by the C terminal kinase domain of MSK1 which is essential for the catalytic activity of the N terminal kinase domain, Once phosphorylated on Thr581 and Ser360 by ERK1/2 and SAPK2/p38, Similar to RSK, MSK1 is a mitogen and stress activated protein kinase 1 which belongs to the AGC family of kinases and is related in structure to the ribosomal p70 S6 kinase subfamily |
| Purification | Purified by Protein A |
| Storage conditions | 50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission | 590nm/617nm |
| Synonyms | MSK1 RLPK |
| Properties | ALEXA FLUOR they should be stored frozen at - 24°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation | 594, ALEXA FLUOR®, Alexa Fluor |
| Conjugated | Alexa conjugate 1 |
| Gene target | MSK1 (Thr581) |
| Short name | MSK1 (Thr581) Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Label | ALEXA FLUOR 594 |
| Alternative name | ALEXA FLUOR 594, MSK1 (Thr581) (Antibody to) |
| Alternative technique | antibodies |
| Identity | 10434 |
| Gene | RPS6KA5 |
| Long gene name | ribosomal protein S6 kinase A5 |
| Synonyms gene name | 90kD, polypeptide 5 , ribosomal protein S6 kinase |
| Locus | 14q32, 11 |
| Discovery year | 1999-03-10 |
| GenBank acession | AF074393 |
| Entrez gene record | 9252 |
| Pubmed identfication | 9687510 10702687 |
| RefSeq identity | NM_004755 |
| Classification | Mitogen-activated protein kinase-activated protein kinases |
| Havana BLAST/BLAT | OTTHUMG00000171055 |