MTA1 Antibody

MTA1 Antibody size: 0.1ml 263

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES

Price 263

Size 0.1ml

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Long name	MTA1 Primary Polyclonal Antibody
Also known as	MTA1 PAb
Category	Primary Antibodies
Conjugation	Unconjugated
Target Antigen	MTA1
Specificity	This is a highly specific antibody against MTA1
Modification(s)	None
Modification site(s)	Unmodified antibody
Clonality	Polyclonal antibody
Clone number	Polyclonal antibody
Concentration	1ug per 1ul
Immunogen range	650-700/715
Subcellular location	Nucleus
Source	This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human MTA1
Gene ID number	9112
Swiss Prot	Q13330
Tested Applications	IF(IHC-P), IHC-P, WB
Recommended dilutions	IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000)
Cross reactivity	Mouse, Rat, Human
Cross reactive species details	not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen	Acts as a transcriptional coactivator of BCAS3, As a part of the histone-deacetylase multiprotein complex (NuRD), ESR1, IFI16 and HDAC4/5/6-dependent manner, In conjunction with other components of NuRD, Involved in the epigenetic regulation of ESR1 expression in breast cancer in a TFAP2C, Isoform Short binds to ESR1 and sequesters it in the cytoplasm and enhances its non-genomic responses, MIP2, PAX5 and SUMO2, Plays a role in the inflammatory responses, Plays a role in the regulation of the circadian clock and is essential for the generation and maintenance of circadian rhythms under constant light and for normal entrainment of behavior to light-dark (LD) cycles, Plays an important role in tumorigenesis, Positively regulates the CLOCK-ARNTL/BMAL1 heterodimer mediated transcriptional activation of its own transcription and the transcription of CRY1, Regulates deacetylation of ARNTL/BMAL1 by regulating SIRT1 expression, Regulates p53-dependent and -independent DNA repair processes following genotoxic stress, Regulates the stability and function of p53/TP53 by inhibiting its ubiquitination by COP1 and MDM2 thereby regulating the p53-dependent DNA repair, Stimulates the expression of WNT1 by inhibiting the expression of its transcriptional corepressor SIX3, TFF1 and CDKN1A, acts as a transcriptional corepressor of BRCA1, and TNF, and metastasis, both as a target and as a component of the NF-kappa-B signaling and regulates a subset of proinflammatory cytokines such as IL1B, independent of the NuRD complex, regulates transcription of its targets by modifying the acetylation status of the target chromatin and cofactor accessibility to the target DNA, resulting in derepressing CRY1-mediated transcription repression, tumor invasion, Transcriptional coregulator which can act as both a transcriptional corepressor and coactivator
Purification method	This antibody was purified via Protein A
Storage conditions	50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names	MTA1, Metastasis-associated protein MTA1
Properties	C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene target	MTA1
Short name	MTA1 Antibody
Technique	antibodies against human proteins, antibodies for, Antibody
Alternative name	MTA1 (Antibody to)
Alternative technique	antibodies
Identity	7410
Gene	MTA1
Long gene name	metastasis associated 1
Locus	14q32, 33
Discovery year	1999-03-12
GenBank acession	U35113
Entrez gene record	9112
Pubmed identfication	8083195 7607577
Classification	GATA zinc finger domain containing NuRD complex Myb/SANT domain containing
Havana BLAST/BLAT	OTTHUMG00000150362

MTA1 Antibody

MTA1 Antibody size: 0.1ml 263

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