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MTA2 Antibody

MTA2 Antibody size: 0.1ml 263

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price 263
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long nameMTA2 Primary Polyclonal Antibody
Also known asMTA2 PAb
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenMTA2
SpecificityThis is a highly specific antibody against MTA2
Modification(s)None
Modification site(s)Unmodified antibody
ClonalityPolyclonal antibody
Clone numberPolyclonal antibody
Concentration1ug per 1ul
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human MTA2
Gene ID number9219
Tested Applications IF(IHC-P), IHC-P, WB
Recommended dilutions IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000)
Cross reactivity Mouse, Rat, Human
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen A similar protein, Elevation of MTA1 levels in these tumors appears to enhance the metastases to lymph nodes, MTA1 contains a single SH3-binding motif and a zinc finger domain, MTA1 functions in conjunction with other components of NURD to mediate transcriptional repression as it facilitates the association of repressor molecules with the chromatin, MTA1 is normally expressed at low levels in various tissues and is more highly expressed in testis, MTA2, Overexpression of MTA1 correlates with tumor invasion and metastasis in various carcinomas including colorectal, Structurally, along with a region similar to the co-repressor protein N-Cor, also designated MTA1-L1 (MTA1-like protein 1), and therefore may be an indicator for assessing the potential malignancies of various tumors, gastrointestinal and breast carcinomas, increase mammary cell motility and potentiate growth, shares more than 55% sequence homology with MTA1 and is ubiquitously expressed, which is associated with ATP-dependent chromatin-remodeling and histone deacetylase activity, MTA1 is a component of the NURD (nucleosome remodeling and histone deacetylation) complex
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names MTA1 L1 protein, MTA1-L1 protein, MTA1L1, MTA1L1: metastasis-associated 1-like 1, MTA2_HUMAN, Metastasis associated 1 family member 2, Metastasis associated 1 like 1, Metastasis associated gene 1 like 1, Metastasis associated gene family member 2, Metastasis associated protein 2, Metastasis associated protein MTA 2, Metastasis associated protein MTA2, Mmta2, P53 target protein in deacetylase complex, PID, Mata1l1
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene targetMTA2
Short nameMTA2 Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameMTA2 (Antibody to)
Alternative techniqueantibodies
Identity 7411
Gene MTA2
Long gene name metastasis associated 1 family member 2
Synonyms gene MTA1L1
Synonyms gene name member 2 , metastasis associated gene family
Synonyms MTA1-L1
Locus 11q12, 3
Discovery year 1999-05-17
GenBank acession AB016591
Entrez gene record 9219
Pubmed identfication 9929979
RefSeq identity NM_004739
Classification GATA zinc finger domain containing NuRD complex Myb/SANT domain containing
Havana BLAST/BLAT OTTHUMG00000167684

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