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MTMR14 Antibody, ALEXA FLUOR 594

MTMR14 Antibody, ALEXA FLUOR 594 size: 100ul 332

Supplier BIOSS PRIMARY CONJUGATED ANTIBODIES
Price 332
Size 100ul
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long name ALEXA FLUOR 594 Conjugated, MTMR14 Polyclonal Antibody
Also known asAnti-MTMR14 PAb ALEXA FLUOR 594
CategoryConjugated Primary Antibodies
Conjugated with 594, ALEXA FLUOR®
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenMTMR14
SpecificityThis is a highly specific antibody against MTMR14
ModificationUnmodified
Modification SiteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human MTMR14
Tested applicationsIF(IHC-P)
Recommended dilutionsIF(IHC-P)(1:50-200)
Crossreactivity Mouse, Rat, Human
Cross-reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the antigen In these studies, In zebrafish, MTMR14 deficiency in mice leads to altered calcium homeostasis and muscle disorders (2), MTMR14 has also been shown to play a role in autophagy, MTMR14 inhibited autophagy and mutations of MTMR14 associated with centronuclear myopathy were also defective in autophagy inhibition, MTMR14 knockdown was shown to increase the number of autophagosomes, MTMR14 was localized to autophagic isolation membranes and early autophagosomes (3), Mutations in the MTMR14 gene have been associated with centronuclear myopathy (1), Vps34 (3), a process that is highly regulated by phosphatidylinositides through the type III PI3K, also known as Jumpy, is a myotubularin-related phosphoinositol-3-phosphate (PI3P) phosphatase (1), suggesting that its activity is associated with an inhibition of autophagy (4), Myotubularin-related protein 14 (MTMR14)
PurificationPurified by Protein A
Storage conditions 50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA
Excitation emission590nm/617nm
Synonyms FLJ22405 FLJ90311 hJumpy hEDTP
Properties ALEXA FLUOR they should be stored frozen at - 24°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate
Conjugation 594, ALEXA FLUOR®, Alexa Fluor
ConjugatedAlexa conjugate 1
Gene targetMTMR14
Short nameMTMR14 Antibody
Technique antibodies against human proteins, antibodies for, Antibody
LabelALEXA FLUOR 594
Alternative name ALEXA FLUOR 594, MTMR14 (Antibody to)
Alternative techniqueantibodies
Identity 26190
Gene MTMR14
Long gene name myotubularin related protein 14
Synonyms gene C3orf29
Synonyms gene name chromosome 3 open reading frame 29
Synonyms name egg-derived tyrosine phosphatase homolog (Drosophila)
Locus 3p25, 3
Discovery year 2005-12-22
GenBank acession BC001674
Entrez gene record 64419
Pubmed identfication 15186772
RefSeq identity NM_022485
Classification Phosphoinositide phosphatases Myotubularins
Havana BLAST/BLAT OTTHUMG00000155111

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