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MTMR14 Antibody, Cy5.5 Conjugated

MTMR14 Antibody, Cy5.5 Conjugated size: 0.1ml 350

Supplier BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price 350
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long name Cy5, 5 Conjugated, MTMR14 Polyclonal Antibody
CategoryConjugated Primary Antibodies
Conjugation Cy5, 5, 5, Cy5
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenMTMR14
SpecificityThis is a highly specific antibody against MTMR14
ModificationUnmodified
Modification siteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
SourceKLH conjugated synthetic peptide derived from human MTMR14
Tested applicationsIF(IHC-P)
Recommended dilutionsIF(IHC-P)(1:50-200)
Crossreactivity Mouse, Rat, Human
Crossreactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background In these studies, In zebrafish, MTMR14 deficiency in mice leads to altered calcium homeostasis and muscle disorders (2), MTMR14 has also been shown to play a role in autophagy, MTMR14 inhibited autophagy and mutations of MTMR14 associated with centronuclear myopathy were also defective in autophagy inhibition, MTMR14 knockdown was shown to increase the number of autophagosomes, MTMR14 was localized to autophagic isolation membranes and early autophagosomes (3), Mutations in the MTMR14 gene have been associated with centronuclear myopathy (1), Vps34 (3), a process that is highly regulated by phosphatidylinositides through the type III PI3K, also known as Jumpy, is a myotubularin-related phosphoinositol-3-phosphate (PI3P) phosphatase (1), suggesting that its activity is associated with an inhibition of autophagy (4), Myotubularin-related protein 14 (MTMR14)
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation Emission675nm/694nm
Synonyms FLJ22405 FLJ90311 hJumpy hEDTP
Properties Cy5 antibodies are excited by the 650-nanometer wave of an argon laser and detected at a 670-nanometer captor, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
ConjugatedThese antibodies are excite for emission at 678nm and detected at a 694 , nm wavelengths
Gene targetMTMR14 Conjugated
Short name Conjugated, MTMR14 Antibody
Technique antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
Label5, Cy5
Alternative name cyanine 5, 5 coupled, MTMR14 (Antibody to)
Alternative techniqueantibodies
Identity 26190
Gene MTMR14
Long gene name myotubularin related protein 14
Synonyms gene C3orf29
Synonyms gene name chromosome 3 open reading frame 29
Synonyms name egg-derived tyrosine phosphatase homolog (Drosophila)
Locus 3p25, 3
Discovery year 2005-12-22
GenBank acession BC001674
Entrez gene record 64419
Pubmed identfication 15186772
RefSeq identity NM_022485
Classification Phosphoinositide phosphatases Myotubularins
Havana BLAST/BLAT OTTHUMG00000155111

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