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MTMR2 Antibody, ALEXA FLUOR 594

MTMR2 Antibody, ALEXA FLUOR 594 size: 100ul 332

Supplier BIOSS PRIMARY CONJUGATED ANTIBODIES
Price 332
Size 100ul
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long name ALEXA FLUOR 594 Conjugated, MTMR2 Polyclonal Antibody
Also known asAnti-MTMR2 PAb ALEXA FLUOR 594
CategoryConjugated Primary Antibodies
Conjugated with 594, ALEXA FLUOR®
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenMTMR2
SpecificityThis is a highly specific antibody against MTMR2
ModificationUnmodified
Modification SiteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human MTMR2
Tested applicationsIF(IHC-P)
Recommended dilutionsIF(IHC-P)(1:50-200)
Crossreactivity Mouse, Rat, Human
Cross-reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the antigen MTMR family members hydrolyze both Phosphatidylinositol 3-phosphate (PtdIns3P) and PtdIns(3, MTMR2 interacts with MTMR5, MTMR3 and MTMR4 can either interact with each other or self associate, MTMR6 regulates the activity of the calcium-activated potassium channel 3, MTMR9 regulates the activity of MTMR7 and MTMR8, Mutations in MTMR2 cause autosomal recessive Charcot-Marie-Tooth type 4B1 (CMT4B1), They are protein tyrosine phosphatases that utilize inositol phospholipids, an inactive family member that increases the enzymatic activity of MTMR2 and dictates its subcellular localization, as substrates, focally folded myelin sheaths and demyelination, rather than phosphoproteins, which is characterized by reduced nerve conduction velocities, 1, 5)P2, Myotubularin and the myotubularin-related proteins (MTMR1-9) belong to a highly conserved family of eukaryotic phosphatases
PurificationPurified by Protein A
Storage conditions 50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA
Excitation emission590nm/617nm
Synonyms KIAA1073
Properties ALEXA FLUOR they should be stored frozen at - 24°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate
Conjugation 594, ALEXA FLUOR®, Alexa Fluor
ConjugatedAlexa conjugate 1
Gene targetMTMR2
Short nameMTMR2 Antibody
Technique antibodies against human proteins, antibodies for, Antibody
LabelALEXA FLUOR 594
Alternative name ALEXA FLUOR 594, MTMR2 (Antibody to)
Alternative techniqueantibodies
Identity 7450
Gene MTMR2
Long gene name myotubularin related protein 2
Synonyms gene CMT4B
Synonyms name phosphatidylinositol-3-phosphatase phosphoinositide-3-phosphatase
Locus 11q21
Discovery year 1999-02-05
GenBank acession U58033
Entrez gene record 8898
Pubmed identfication 8640223 9736772
RefSeq identity NM_016156
Classification Phosphoinositide phosphatases Myotubularins
Havana BLAST/BLAT OTTHUMG00000153837
Locus Specific Databases Inherited Peripheral Neuropathies Mutation Database LRG_257

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