mTOR (53E11) Monoclonal Antibody

mTOR (53E11) Monoclonal Antibody size: 0.1ml 362

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES

Price 362

Size 0.1ml

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Long name	mTOR (53E11) Monoclonal Antibody
Also known as	mTOR (53E11) Monoclonal Antibody
Category	Primary Antibodies
Conjugation	Unconjugated
Target Antigen	mTOR
Specificity	This is a highly specific antibody against mTOR
Modification(s)	None
Modification site(s)	Unmodified antibody
Clonality	Monoclonal
Clone number	5300000000000
Source	Recombinant human protein purified from E, coli (His-mTOR)
Gene ID number	2475
Swiss Prot	P42345
Tested Applications	WB
Recommended dilutions	000), WB (1:2
Cross reactivity	Human
Cross reactive species details	not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen	Activated mTORC1 up-regulates protein synthesis by phosphorylating key regulators of mRNA translation and ribosome synthesis, As a Kinase subunit of both mTORC1(complex1) and mTORC2(complex2), a serine/threonine kinase involved in diverse cellular processes, and protein stability, at least in part, including protein translation, mRNA turnover, mTOR regulates cell growth and survival in response to nutrient and hormonal signals, mTORC1 is activated in response to growth factors or amino-acids, mTORC1 phosphorylates EIF4EBP1 and releases it from inhibiting the elongation initiation factor 4E (eiF4E), mTORC2 plays a critical role in AKT1 'Ser-473' phosphorylation, mTORC2 promotes the serum-induced formation of stress-fibers or F-actin, mTORC2 seems to function upstream of Rho GTPases to regulate the actin cytoskeleton, mediates, probably by activating one or more Rho-type guanine nucleotide exchange factors, some of the biological actions of Akt, Mammalian target of rapamycin (mTOR)
Storage conditions	50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names	FK506-binding protein 12-rapamycin complex-associated protein 1, FKBP12-rapamycin complex-associated protein, FRAP, FRAP1, FRAP2, Mammalian target of rapamycin, Mechanistic target of rapamycin, RAFT1, RAPT1, Rapamycin and FKBP12 target 1, Rapamycin target protein 1, Serine/threonine-protein kinase mTOR, mTOR, SKS
Properties	C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
About	Each murine monoclonal anibody has his own affinity specific for the clone, Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes, Monoclonals of this antigen are available in different clones
Gene target	mTOR (53E11) Monoclonal
Short name	mTOR (53E11) Monoclonal Antibody
Technique	Monoclonals or monoclonal antibodies, antibodies against human proteins, antibodies for, Antibody
Alternative name	Mammalian target on rapamycin (53E11) monoclonal (Antibody to)
Alternative technique	antibodies

mTOR (53E11) Monoclonal Antibody

mTOR (53E11) Monoclonal Antibody size: 0.1ml 362

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