Name : mTOR (Thr2446) Antibody
Supplier : BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price :281
SKU : GEN5826914607
| Long name | mTOR (Thr2446) Primary Polyclonal Antibody |
| Also known as | mTOR (Thr2446) PAb |
| Category | Primary Antibodies |
| Conjugation | Unconjugated |
| Target Antigen | mTOR Thr2446 |
| Specificity | This is a highly specific antibody against mTOR Thr2446 |
| Modification(s) | Phosphorylation |
| Modification site(s) | Thr2446 |
| Clonality | Polyclonal antibody |
| Clone number | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Source | KLH conjugated synthetic phosphopeptide derived from human mTOR around the phosphorylation site of Thr2446 |
| Gene ID number | 1735 |
| Tested Applications | IF(IHC-P), IHC-P, WB |
| Recommended dilutions | IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity | Mouse, Rat, Human |
| Cross reactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen | DNA recombination, In rat, The FKBP12-rapamycin complex is known to inhibit progression through the G1 cell cycle stage by interfering with mitogenic signaling pathways involved in G1 progression in several cell types, The binding of FRAP to FKBP12-rapamycin correlated with the ability of these ligands to inhibit cell cycle progression, and DNA damage detection, as well as in yeast, it is a 289-kDa protein (symbolized RAFT1) with significant homology to the Saccharomyces cerevisiae protein TOR1 and has been shown to associate with the immunophilin FKBP12 in a rapamycin dependent fashion, mTOR is one of a family of proteins involved in cell cycle progression |
| Purification method | This antibody was purified via Protein A |
| Storage conditions | 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names | FK506 binding protein 12 rapamycin associated protein 1, FK506 binding protein 12 rapamycin associated protein 2, FK506 binding protein 12 rapamycin complex associated protein 1, FK506 binding protein12-rapamycin associated protein 1, FK506 binding protein12-rapamycin associated protein 2, FK506-binding protein 12-rapamycin complex-associated protein 1, FKBP rapamycin associated protein, FKBP12 rapamycin complex associated protein, FKBP12-rapamycin complex-associated protein, FLJ44809, FRAP, FRAP1, FRAP2, MTOR_HUMAN, Mammalian target of rapamycin, Mechanistic target of rapamycin, OTTHUMP00000001983, RAFT1, RAPT1, Rapamycin and FKBP12 target 1, Rapamycin associated protein FRAP2, Rapamycin target protein, Rapamycin target protein 1, Serine/threonine-protein kinase mTOR, mTOR, 1 FK506 binding protein 12 rapamycin associated protein 1, dJ576K7 |
| Properties | C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target | mTOR (Thr2446) |
| Short name | mTOR (Thr2446) Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Alternative name | Mammalian target on rapamycin (Thr2446) (Antibody to) |
| Alternative technique | antibodies |