Name : MUC1 (347CT26.1.3) Monoclonal Antibody
Supplier : BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price :211
SKU : GEN9415536834
| Long name | 1, 3) Monoclonal Antibody, MUC1 (347CT26 |
| Also known as | 1, 3) Monoclonal Antibody, MUC1 (347CT26 |
| Category | Primary Antibodies |
| Conjugation | Unconjugated |
| Target Antigen | MUC1 |
| Specificity | This is a highly specific antibody against MUC1 |
| Modification(s) | None |
| Modification site(s) | Unmodified antibody |
| Clonality | Monoclonal |
| Clone number | 1, 3, 347CT26 |
| Source | Purified His-tagged MUC1 protein(Fragment) was used to produced this monoclonal antibody |
| Gene ID number | 4582 |
| Swiss Prot | P15941 |
| Tested Applications | WB |
| Recommended dilutions | WB(1:100~250) |
| Cross reactivity | Human |
| Cross reactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen | Binds, Can act both as an adhesion and an anti-adhesion protein, In activated T-cells, May provide a protective layer on epithelial cells against bacterial and enzyme attack, Modulates signaling in ERK, Promotes tumor progression, Regulates TP53-mediated transcription and determines cell fate in the genotoxic stress response, SRC and NF-kappa-B pathways, The beta subunit contains a C-terminal domain which is involved in cell signaling, influences directly or indirectly the Ras/MAPK pathway, the PE21 promoter element of TP53 and represses TP53 activity, through phosphorylations and protein-protein interactions, together with KLF4, The alpha subunit has cell adhesive properties |
| Purification method | This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS, 09% (W/V) sodium azide, Purified monoclonal antibody supplied in PBS with 0 |
| Storage conditions | 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names | ADMCKD, ADMCKD1, Breast carcinoma-associated antigen DF3, CA 15-3, CD227, Cancer antigen 15-3, Carcinoma-associated mucin, Episialin, H23AG, KL-6, Krebs von den Lungen-6, MAM6, MCD, MCKD, MCKD1, MUC-1, MUC-1/SEC, MUC-1/X, MUC1, MUC1/ZD, Mucin-1, PEM, PEMT, PUM, Peanut-reactive urinary mucin, Polymorphic epithelial mucin, Tumor-associated epithelial membrane antigen, Tumor-associated mucin, EMA |
| Properties | C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| About | Each murine monoclonal anibody has his own affinity specific for the clone, Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes, Monoclonals of this antigen are available in different clones |
| Gene target | 1, 3) Monoclonal, MUC1 (347CT26 |
| Short name | 1, 3) Monoclonal Antibody, MUC1 (347CT26 |
| Technique | Monoclonals or monoclonal antibodies, antibodies against human proteins, antibodies for, Antibody |
| Alternative name | 1, 3) monoclonal (Antibody to), MUC1 (347CT26 |
| Alternative technique | antibodies |
| Identity | 7508 |
| Gene | MUC1 |
| Long gene name | cell surface associated , mucin 1 |
| Synonyms gene | PUM MCKD1 |
| Synonyms gene name | mucin 1, transmembrane medullary cystic kidney disease 1 (autosomal dominant) |
| Synonyms | CD227 PEM ADMCKD ADMCKD1 MCKD MCD |
| Locus | 1q22 |
| Discovery year | 1986-01-01 |
| GenBank acession | J05581 |
| Entrez gene record | 4582 |
| Pubmed identfication | 1697589 23396133 |
| RefSeq identity | NM_002456 |
| Classification | Mucins CD molecules |
| Havana BLAST/BLAT | OTTHUMG00000035681 |