Name : MUC1 Antibody (phospho-T1224)
Supplier : NJS POLY
Price :199
SKU : GEN3788363865
| Category | Antibody |
| Concentration | pH 7, with 0, 09% sodium azide, 4, In 1X PBS |
| Form | Antigen affinity purified |
| Conjugation | Unconjugated |
| Clone | Polyclonal antibody |
| Recognised antigen | MUC1 (phospho-T1224) |
| Host animal | Rabbit (Oryctolagus cuniculus) |
| Clonality | Polyclonal (rabbit origin) |
| Species reactivity | Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens) |
| Tested applications | ELISA, IF, DB |
| Recommended dilutions | Dot blot: 1:500, Immunofluorescence: 1:10-1:50 |
| Notes | Titration of the phospho-MUC1 antibody may be required due to differences in protocols and secondary/substrate sensitivity |
| Intented use | This phospho-MUC1 antibodyis to be used only for research purposes and not for diagnostics |
| Uniprot # | P15941 |
| Purity | Antigen affinity |
| Description | It also includes a 20 aa variable number tandem repeat (VNTR) domain, Overexpression, The protein is anchored to the apical surface of many epithelia by a transmembrane domain, The protein serves a protective function by binding to pathogens and also functions in a cell signaling capacity, aberrant intracellular localization, and changes in glycosylation of this protein have been associated with carcinomas, glycosylated phosphoprotein, with the degree of glycosylation varying with cell type, with the number of repeats varying from 20 to 120 in different individuals, MUC1 is a member of the mucin family and encodes a membrane bound |
| Immunogen | This phospho-MUC1 antibody was produced from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding pT1224 of human MUC1 |
| Storage | Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, Aliquot the phospho-MUC1 antibody and store frozen at -20 deg |
| Properties | C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target | MUC1 (phospho-T1224) |
| Short name | MUC1 Antibody (phospho-T1224) |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Alternative name | MUC1 (Antibody to) (phosphorilated-T1224) |
| Alternative technique | antibodies |
| Identity | 7508 |
| Gene | MUC1 |
| Long gene name | cell surface associated , mucin 1 |
| Synonyms gene | PUM MCKD1 |
| Synonyms gene name | mucin 1, transmembrane medullary cystic kidney disease 1 (autosomal dominant) |
| Synonyms | CD227 PEM ADMCKD ADMCKD1 MCKD MCD |
| Locus | 1q22 |
| Discovery year | 1986-01-01 |
| GenBank acession | J05581 |
| Entrez gene record | 4582 |
| Pubmed identfication | 1697589 23396133 |
| RefSeq identity | NM_002456 |
| Classification | Mucins CD molecules |
| Havana BLAST/BLAT | OTTHUMG00000035681 |