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MUC18/ CD146 Antibody

MUC18/ CD146 Antibody size: 100ug 354

Supplier MBS MONO
Price 354
Size 100ug
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Also known asMUC18
Other names CD_antigen: CD146, Cell surface glycoprotein MUC18, Cell surface glycoprotein P1H12, Gicerin, Melanoma cell adhesion molecule, Melanoma-associated antigen A32, Melanoma-associated antigen MUC18, S-endo 1 endothelial-associated antigen, S-endo 1 endothelial-associated antigen, cell surface glycoprotein MUC18, cell surface glycoprotein P1H12, melanoma adhesion molecule, melanoma cell adhesion molecule, melanoma-associated antigen A32, melanoma-associated antigen MUC18, N/A
CategoryAntibodies
SubcategoryMnoclonal antibodies
Gene nameMCAM
Gene name synonimsN/A
Other gene names CD146, MCAM, MUC18, MUC18, MCAM
ClonalityMonoclonal
Immunoglobulin isotype kappa, IgG1
CloneOJ79c
Host organismMouse (Mus musculus)
Species reactivity Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby, Human (Homo sapiens)
Specificity and cross-reactivity MUC 18 or CD146, Mel-CAM expression is restricted to advanced primary and metastatic melanomas and to cell lines of the neuroectodermal lineage, Mel-CAM is found on 80% of advanced primary human melanomas and correlates well with development of metastatic disease, Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited, This particular antibody might cross react with speacies outside of the listed ones, also designated MCAM, but not normal melanocytes, that belongs to the immunoglobulin superfamily and functions as a Ca2+-independent cell adhesion molecule, The human Mel-CAM gene maps to chromosome 11q23 and encodes a trans-membrane glycoprotein
Purification methodN/A
Form/AppearanceN/A
ConcentrationN/A
Storage and shipping Antibody is stable for 24 months, Temperature variations in the range of 1 to 7 degrees Celsius are tolerable, We recommend NOT to freeze the antibody, Store the antibody at +4C
Tested applications: Flow Cytometry (0, Immunofluorescence (0, Immunohistology (Frozen) (0, Immunoprecipitation (1-2ug/500ug protein), Western Blot (0, order antibody without BSA), 0ug/ml for 30 min at RT Opt, 0ug/ml), 0ug/ml), 5-1, 5-1, 5-1, 5-1ug/million cells), ELISA (For coating
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by MBS mono they should be stored frozen at - 24°
Gene targetMUC18/ CD146
Short nameMUC18/ CD146 Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameMUC18/ CD146 (Antibody to)
Alternative techniqueantibodies
Identity 6934
Gene MCAM
Long gene name melanoma cell adhesion molecule
Synonyms MUC18 CD146
Synonyms name Gicerin
Locus 11q23, 3
Discovery year 1995-12-18
GenBank acession X68264
Entrez gene record 4162
Pubmed identfication 2602381 10702685
Classification C2-set domain containing CD molecules V-set domain containing Immunoglobulin like domain containing
Havana BLAST/BLAT OTTHUMG00000166197

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