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MUC5AC Antibody Mucin-5AC

MUC5AC Antibody Mucin-5AC size: 0.1mg 406

Supplier NJS POLY
Price 406
Size 0.1mg
CategoryAntibody
Concentration2ml sterile DI water, 5mg/ml if reconstituted with 0
FormAntigen affinity purified
ConjugationUnconjugated
ClonePolyclonal antibody
Recognised antigenMUC5AC Mucin-5AC
Host animalRabbit (Oryctolagus cuniculus)
ClonalityPolyclonal (rabbit origin)
Species reactivity Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens)
Tested applications IHC-P, WB
Recommended dilutions5-1ug/ml, 5-1ug/ml, IHC (Paraffin): 0, Western blot: 0
Notes Titration of the MUC5AC antibody may be required due to differences in protocols and secondary/substrate sensitivity, The stated application concentrations are suggested starting points
Intented useThis MUC5AC antibodyis to be used only for research purposes and not for diagnostics
Gene ID #4586
PurityAntigen affinity
Description It has been showed that activation of the NF-kappa-B signaling pathway by inflammatory cytokine TNF-alpha upregulated MUC5AC mRNA expression nearly 6-fold, It is also a direct and critical mediator of resistance during intestinal nematode infection, It is mapped to 11p15, MUC5AC is highly expressed in adult trachea and stomach, This gene has been linked to mucus hypersecretion in the pulmonary tracts and associated to chronic obstructive pulmonary disease(COPD), 5, Mucin-5AC is a protein that in humans is encoded by the MUC5AC gene
ImmunogenHuman partial recombinant protein (4848-5030) was used as the immunogen for this MUC5AC antibody
Storage Avoid repeated freezing and thawing, Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, For long-term, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, aliquot and store at -20 deg, the MUC5AC antibody can be stored for up to one month at 4oC, After reconstitution
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°
Gene targetMUC5AC Mucin-5AC
Short nameMUC5AC Antibody Mucin-5AC
Technique antibodies against human proteins, antibodies for, Antibody
Alternative name oli this GO meric mucus/electrophoretic matrix-forming (Antibody to) Mucin-5AC, mucin 5AC
Alternative techniqueantibodies
Alternative to gene target IDBG-645651 and IDBG-645651 and ENSBTAG00000038262 and, MUC5AC and IDBG-229951 and ENSG00000215182 and 4586, Muc5ac and IDBG-212386 and ENSMUSG00000037974 and 17833, leB and MUC5 and TBM, multiple, oli this GO meric mucus/gel-forming, protein binding, this GO :0005515 and protein binding and molecular function, this GO :0005515: protein binding, this GO :0005515: protein binding, mucin 5AC
Identity 7515
Gene MUC5AC
Long gene name mucin 5AC, oligomeric mucus/gel-forming
Synonyms gene name mucin 5, subtypes A and C, tracheobronchial/gastric
Synonyms MUC5
Locus 11p15, 5
Discovery year 1995-04-05
GenBank acession AJ001402 AJ298317
Entrez gene record 4586
Pubmed identfication 7826332 9588204
RefSeq identity XM_001130382
Classification Mucins
Havana BLAST/BLAT OTTHUMG00000154270

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