Name : MUL1 Antibody, FITC Conjugated
Supplier : BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price :333
SKU : GEN6535404019
| Long name | FITC Conjugated, MUL1 Polyclonal Antibody |
| Category | Conjugated Primary Antibodies |
| Conjugation | Anti-FITC Antibody |
| Host Organism | Rabbit (Oryctolagus cuniculus) |
| Target Antigen | MUL1 |
| Specificity | This is a highly specific antibody against MUL1 |
| Modification | Unmodified |
| Modification site | None |
| Clonality | Polyclonal |
| Clone | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Source | KLH conjugated synthetic peptide derived from human MUL1/RNF218 |
| Gene ID number | 79594 |
| Tested applications | IF(IHC-P) |
| Recommended dilutions | IF(IHC-P)(1:50-200) |
| Crossreactivity | Mouse, Rat, Human |
| Crossreactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background | E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugatin, Inhibits cell growth, Promotes mitochondrial fragmentation and influences mitochondrial localization, When overexpressed, activates JNK through MAP3K7/TAK1 and induces caspase-dependent apoptosis, E3 ubiquitin-protein ligase that plays a role in the control of mitochondrial morphology |
| Purification method | This antibody was purified via Protein A |
| Storage conditions | 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission | 494nm/518nm |
| Synonyms | FLJ12875 MULAN RNF218 MAPL GIDE |
| Properties | Bioss Primary Conjugated Antibodies FITC is highly sensitive to pH extremes, FITC has a green emission that's usually collected at 530 nanometers, FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light, For fluorescent microscopy applications, This Bioss Primary Conjugated Antibodies Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS, When excited at 488 nanometers, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, the FL1 detector of a FACSCalibur or FACScan, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target | MUL1 Conjugated |
| Short name | FITC Conjugated, MUL1 Antibody |
| Technique | Fluorescein, antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label | FITC |
| Alternative name | fluorecein coupled, mitochondrial E3 ubiquitin protein ligase 1 (Antibody to) |
| Alternative technique | antibodies |
| Alternative to gene target | MUL1 and IDBG-645664 and ENSBTAG00000020850 and 508406, MUL1 and IDBG-92888 and ENSG00000090432 and 79594, Mul1 and IDBG-199848 and ENSMUSG00000041241 and 68350, identical protein binding, nuclei, this GO :0000266 and mitochondrial fission and biological process this GO :0004842 and ubiquitin-protein transferase activity and molecular function this GO :0004871 and signal transducer activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0005739 and mitochondrion and cellular component this GO :0005777 and peroxisome and cellular component this GO :0006919 and activation of cysteine-type endopeptidase activity involved in apoptotic process and biological process this GO :0007005 and mitochondrion organization and biological process this GO :0007257 and activation of JUN kinase activity and biological process this GO :0008270 and zinc ion binding and molecular function this GO :0010637 and negative regulation of mitochondrial fusion and biological process this GO :0016020 and membrane and cellular component this GO :0016567 and protein ubiquitination and biological process this GO :0016925 and protein sumoylation and biological process this GO :0019789 and SUMO ligase activity and molecular function this GO :0030308 and negative regulation of cell growth and biological process this GO :0031307 and integral component of mitochondrial outer membrane and cellular component this GO :0031625 and ubiquitin protein ligase binding and molecular function this GO :0033235 and positive regulation of protein sumoylation and biological process this GO :0042802 and identical protein binding and molecular function this GO :0043123 and positive regulation of I-kappaB kinase/NF-kappaB signaling and biological process this GO :0045087 and innate immune response and biological process this GO :0045824 and negative regulation of innate immune response and biological process this GO :0050689 and negative regulation of defense response to virus by host and biological process this GO :0050821 and protein stabilization and biological process this GO :0051646 and mitochondrion localization and biological process this GO :0051898 and negative regulation of protein kinase B signaling and biological process this GO :0060339 and negative regulation of type I interferon-mediated signaling pathway and biological process this GO :0071360 and cellular response to exogenous dsRNA and biological process this GO :0071650 and negative regulation of chemokine (C-C motif) ligand 5 production and biological process this GO :0090141 and positive regulation of mitochondrial fission and biological process this GO :1901028 and regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway and biological process, this GO :0004842: ubiquitin-protein transferase activity, this GO :0004842: ubiquitin-protein transferase activity and also this GO :0004871: signal transducer activity and also this GO :0005515: protein binding and also this GO :0008270: zinc ion binding and also this GO :0019789: SUMO ligase activity and also this GO :0031625: ubiquitin protein ligase binding and also this GO :0042802: identical protein binding, this GO :0004871: signal transducer activity, this GO :0005515: protein binding, this GO :0008270: zinc ion binding, this GO :0019789: SUMO ligase activity, this GO :0031625: ubiquitin protein ligase binding, this GO :0042802: identical protein binding, mitochondrial E3 ubiquitin protein ligase 1 |
| Identity | 25762 |
| Gene | MUL1 |
| Long gene name | mitochondrial E3 ubiquitin protein ligase 1 |
| Synonyms gene | C1orf166 |
| Synonyms gene name | chromosome 1 open reading frame 166 |
| Synonyms name | ring finger protein 218 mitochondria-anchored protein ligase growth inhibition and death E3 ligase mitochondrial ubiquitin ligase activator of NFKB 1 |
| Locus | 1p36, 12 |
| Discovery year | 2005-07-19 |
| GenBank acession | BC014010 |
| Entrez gene record | 79594 |
| Pubmed identfication | 18591963 12761501 18213395 18207745 |
| RefSeq identity | NM_024544 |
| Classification | Ring finger proteins |
| Havana BLAST/BLAT | OTTHUMG00000002838 |