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MUNC18-1 Antibody / STXBP1

MUNC18-1 Antibody / STXBP1 size: 0.1mg 406

Supplier NJS POLY
Price 406
Size 0.1mg
CategoryAntibody
Concentration2ml sterile DI water, 5mg/ml if reconstituted with 0
FormAntigen affinity purified
ConjugationUnconjugated
ClonePolyclonal antibody
Recognised antigenMUNC18-1 / STXBP1
Host animalRabbit (Oryctolagus cuniculus)
ClonalityPolyclonal (rabbit origin)
Species reactivity Due to limited knowledge and inability to test the antibody against all known species, Mouse (Mus musculus), Rat , we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens)
Tested applications IHC-P, WB
Recommended dilutions1-0, 5-1ug/ml, 5ug/ml, IHC (Paraffin): 0, Western blot: 0
NotesOptimal dilution of the MUNC18-1 antibody should be determined by the researcher
Intented useThis MUNC18-1 antibodyis to be used only for research purposes and not for diagnostics
Uniprot #P61764
PurityAntigen affinity
Description Alternatively spliced transcript variants have been described, By fluorescence in situ hybridization, Mutations in this gene have been associated with infantile epileptic encephalopathy-4, The encoded protein appears to play a role in release of neurotransmitters via regulation of syntaxin, This gene encodes a syntaxin-binding protein, a transmembrane attachment protein receptor, also known as Munc18-1, is a protein that in humans is encoded by the STXBP1 gene, the STXBP1 gene is mapped to chromosome 9q34, 1, Syntaxin-binding protein 1
ImmunogenAmino acids KEYPAVRYRGEYKDNALLAQLIQDKLDAYKADD of human MUNC18-1 were used as the immunogen for the MUNC18-1 antibody
Storage Avoid repeated freezing and thawing, Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, aliquot and store at -20 deg, the MUNC18-1 antibody may be kept for up to one month refrigerated at +4 degrees C, After reconstitution, For long-term
Localization membranous, Cytoplasmic
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°
Gene targetMUNC18-1 / STXBP1
Short nameMUNC18-1 Antibody / STXBP1
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameMUNC18-1 (Antibody to) / syntaxin binding protein 1
Alternative techniqueantibodies
Alternative to gene target GABAergic and biological process this GO :0042802 and identical protein binding and molecular function this GO :0043234 and protein complex and cellular component this GO :0043524 and negative regulation of neuron apoptotic process and biological process this GO :0044281 and small molecule metabolic process and biological process this GO :0044822 and poly(A) RNA binding and molecular function this GO :0045921 and positive regulation of exocytosis and biological process this GO :0045956 and positive regulation of calcium ion-dependent exocytosis and biological process this GO :0047485 and protein N-terminus binding and molecular function this GO :0050796 and regulation of insulin secretion and biological process this GO :0050821 and protein stabilization and biological process this GO :0060292 and long term synaptic depression and biological process this GO :0070062 and extracellular vesicular exosome and cellular component this GO :0070527 and platelet aggregation and biological process, MUNC18-1 and NSEC1 and P67 and RBSEC1 and UNC18, Plasma membranes, STXBP1 and IDBG-638972 and ENSBTAG00000003525 and 282378, STXBP1 and IDBG-86143 and ENSG00000136854 and 6812, Stxbp1 and IDBG-161623 and ENSMUSG00000026797 and 20910, protein N-terminus binding, this GO :0000149 and SNARE binding and molecular function this GO :0002576 and platelet degranulation and biological process this GO :0005515 and protein binding and molecular function this GO :0005737 and cytoplasm and cellular component this GO :0005739 and mitochondrion and cellular component this GO :0005829 and cytosol and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0006112 and energy reserve metabolic process and biological process this GO :0006887 and exocytosis and biological process this GO :0006904 and vesicle docking involved in exocytosis and biological process this GO :0007268 and synaptic transmission and biological process this GO :0007269 and neurotransmitter secretion and biological process this GO :0007274 and neuromuscular synaptic transmission and biological process this GO :0007412 and axon target recognition and biological process this GO :0010807 and regulation of synaptic vesicle priming and biological process this GO :0014047 and glutamate secretion and biological process this GO :0015031 and protein transport and biological process this GO :0016188 and synaptic vesicle maturation and biological process this GO :0016192 and vesicle-mediated transport and biological process this GO :0017075 and syntaxin-1 binding and molecular function this GO :0019901 and protein kinase binding and molecular function this GO :0019904 and protein domain specific binding and molecular function this GO :0019905 and syntaxin binding and molecular function this GO :0031091 and platelet alpha granule and cellular component this GO :0032229 and negative regulation of synaptic transmission, this GO :0000149: SNARE binding, this GO :0000149: SNARE binding and also this GO :0005515: protein binding and also this GO :0017075: syntaxin-1 binding and also this GO :0019901: protein kinase binding and also this GO :0019904: protein domain specific binding and also this GO :0019905: syntaxin binding and also this GO :0042802: identical protein binding and also this GO :0044822: poly(A) RNA binding and also this GO :0047485: protein N-terminus binding, this GO :0005515: protein binding, this GO :0017075: syntaxin-1 binding, this GO :0019901: protein kinase binding, this GO :0019904: protein domain specific binding, this GO :0019905: syntaxin binding, this GO :0042802: identical protein binding, this GO :0044822: poly(A) RNA binding, this GO :0047485: protein N-terminus binding, syntaxin binding protein 1
Identity 11444
Gene STXBP1
Long gene name syntaxin binding protein 1
Synonyms hUNC18 MUNC18-1 UNC18 rbSec1
Synonyms name syntaxin-binding protein 1
Locus 9q34, 11
Discovery year 1996-12-27
GenBank acession AF004563
Entrez gene record 6812
Pubmed identfication 9545644
RefSeq identity NM_003165
Havana BLAST/BLAT OTTHUMG00000020713

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