Name : MX1 (474CT4.1.5) Monoclonal Antibody
Supplier : BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price :211
SKU : GEN8389726604
| Long name | 1, 5) Monoclonal Antibody, MX1 (474CT4 |
| Also known as | 1, 5) Monoclonal Antibody, MX1 (474CT4 |
| Category | Primary Antibodies |
| Conjugation | Unconjugated |
| Target Antigen | MX1 |
| Specificity | This is a highly specific antibody against MX1 |
| Modification(s) | None |
| Modification site(s) | Unmodified antibody |
| Clonality | Monoclonal |
| Clone number | 1, 474CT4, 5 |
| Source | This MX1 antibody is generated from mice immunized with a KLH conjugated synthetic peptide between 617-646 amino acids from human MX1 |
| Gene ID number | 4599 |
| Swiss Prot | P20591 |
| Tested Applications | WB |
| Recommended dilutions | WB(1:100~500) |
| Cross reactivity | Human |
| Cross reactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen | Enhances ER stress-mediated cell death after influenza virus infection, Inhibits La Crosse virus (LACV) replication by sequestering viral nucleoprotein in perinuclear complexes, Inhibits influenza A virus (IAV) replication by decreasing or delaying NP synthesis and by blocking endocytic traffic of incoming virus particles, Inhibits thogoto virus (THOV) replication by preventing the nuclear import of viral nucleocapsids, Its target viruses include negative-stranded RNA viruses and HBV through binding and inactivation of their ribonucleocapsid, May also antagonize reoviridae and asfarviridae replication, May regulate the calcium channel activity of TRPCs, and egress, budding, preventing genome amplification, Interferon-induced dynamin-like GTPase with antiviral activity against a wide range of RNA viruses and some DNA viruses |
| Purification method | This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS, 09% (W/V) sodium azide, Purified monoclonal antibody supplied in PBS with 0 |
| Storage conditions | 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names | IFI-78K, IFI78, Interferon-induced GTP-binding protein Mx1, Interferon-induced protein p78, Interferon-regulated resistance GTP-binding protein MxA, MX1, MxA, Myxoma resistance protein 1, Myxovirus resistance protein 1, MX |
| Properties | C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| About | Each murine monoclonal anibody has his own affinity specific for the clone, Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes, Monoclonals of this antigen are available in different clones |
| Gene target | 1, 5) Monoclonal, MX1 (474CT4 |
| Short name | 1, 5) Monoclonal Antibody, MX1 (474CT4 |
| Technique | Monoclonals or monoclonal antibodies, antibodies against human proteins, antibodies for, Antibody |
| Alternative name | interferon-inducible protein p78 (mouse) (474CT4, 1, 5) monoclonal (Antibody to), myxovirus (influenza virus) resistance 1 |
| Alternative technique | antibodies |
| Alternative to gene target | GTP binding, IFI-78K and IFI78 and MX and MxA, MX1 and IDBG-3941 and ENSG00000157601 and 4599, MX1 and IDBG-639306 and ENSBTAG00000030913 and 280872, interferon-inducible protein p78 (mouse), nuclei, this GO :0003924 and GTPase activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005525 and GTP binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0005789 and endoplasmic reticulum membrane and cellular component this GO :0005829 and cytosol and cellular component this GO :0006184 and GTP catabolic process and biological process this GO :0006915 and apoptotic process and biological process this GO :0006952 and defense response and biological process this GO :0007165 and signal transduction and biological process this GO :0009615 and response to virus and biological process this GO :0019221 and cytokine-mediated signaling pathway and biological process this GO :0034340 and response to type I interferon and biological process this GO :0045071 and negative regulation of viral genome replication and biological process this GO :0045087 and innate immune response and biological process this GO :0048471 and perinuclear region of cytoplasm and cellular component this GO :0051607 and defense response to virus and biological process this GO :0060337 and type I interferon signaling pathway and biological process, this GO :0003924: GTPase activity, this GO :0003924: GTPase activity and also this GO :0005515: protein binding and also this GO :0005525: GTP binding, this GO :0005515: protein binding, this GO :0005525: GTP binding, myxovirus (influenza virus) resistance 1 |
| Identity | 7532 |
| Gene | MX1 |
| Long gene name | MX dynamin like GTPase 1 |
| Synonyms gene name | homolog of murine (interferon-inducible protein p78) myxovirus (influenza virus) resistance 1, interferon-inducible protein p78 (mouse) , myxovirus (influenza) resistance 1 |
| Synonyms | IFI-78K MxA |
| Synonyms name | interferon-inducible protein p78 |
| Locus | 21q22, 3 |
| Discovery year | 1988-05-11 |
| Entrez gene record | 4599 |
| Pubmed identfication | 17570575 |
| Havana BLAST/BLAT | OTTHUMG00000086755 |