| Long name | MyD88 Primary Polyclonal Antibody |
| Also known as | MyD88 PAb |
| Category | Primary Antibodies |
| Conjugation | Unconjugated |
| Target Antigen | MyD88 |
| Specificity | This is a highly specific antibody against MyD88 |
| Modification(s) | None |
| Modification site(s) | Unmodified antibody |
| Clonality | Polyclonal antibody |
| Clone number | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Immunogen range | 240-290/296 |
| Subcellular location | Cytoplasm |
| Source | KLH conjugated synthetic peptide derived from mouse MyD88 |
| Gene ID number | 17874 |
| Swiss Prot | P22366 |
| Tested Applications | IF(IHC-P), IHC-P, WB |
| Recommended dilutions | IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity | Mouse, Rat, Human |
| Cross reactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen | Activates IRF1 resulting in its rapid migration into the nucleus to mediate an efficient induction of IFN-beta, Acts via IRAK1, IRAK2, IRF7 and TRAF6, Increases IL-8 transcription, Involved in IL-18-mediated signaling pathway, Isoform 2 is defective in its ability to induce IRAK phosphorylation and NF-kappa-B activation and can function as a negative regulator of activation by IL-1 or lipopolysaccharide (LPS), MyD88-mediated signaling in intestinal epithelial cells is crucial for maintenance of gut homeostasis and controls the expression of the antimicrobial lectin REG3G in the small intestine, NOS2/INOS, and IL12A genes, cytokine secretion and the inflammatory response, leading to NF-kappa-B activation, Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response |
| Purification method | This antibody was purified via Protein A |
| Storage conditions | 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names | Myd88, Myeloid differentiation primary response protein MyD88 |
| Properties | C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target | MyD88 |
| Short name | MyD88 Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Alternative name | myeloid differentiation primary response 88 (Antibody to) |
| Alternative technique | antibodies |
| Identity | 7562 |
| Gene | MYD88 |
| Long gene name | myeloid differentiation primary response 88 |
| Synonyms gene name | myeloid differentiation primary response gene (88) |
| Locus | 3p22, 2 |
| Discovery year | 1997-12-23 |
| GenBank acession | U84408 |
| Entrez gene record | 4615 |
| Pubmed identfication | 9013863 |
| RefSeq identity | NM_002468 |
| Classification | TIR domain containing |
| Havana BLAST/BLAT | OTTHUMG00000131083 |
| Locus Specific Databases | LRG_157 |
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