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MyD88 Antibody, ALEXA FLUOR 488

MyD88 Antibody, ALEXA FLUOR 488 size: 100ul 332

Supplier BIOSS PRIMARY CONJUGATED ANTIBODIES
Price 332
Size 100ul
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long name ALEXA FLUOR 488 Conjugated, MyD88 Polyclonal Antibody
Also known asAnti-MyD88 PAb ALEXA FLUOR 488
CategoryConjugated Primary Antibodies
Conjugated with 488, ALEXA FLUOR®
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenMyD88
SpecificityThis is a highly specific antibody against MyD88
ModificationUnmodified
Modification SiteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
Immunogen range240-290/296
Subcellular locationCytoplasm
SourceKLH conjugated synthetic peptide derived from mouse MyD88
Gene ID Number17874
Swiss ProtP22366
Tested applicationsIF(IHC-P)
Recommended dilutionsIF(IHC-P)(1:50-200)
Crossreactivity Mouse, Rat, Human
Cross-reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the antigen Activates IRF1 resulting in its rapid migration into the nucleus to mediate an efficient induction of IFN-beta, Acts via IRAK1, IRAK2, IRF7 and TRAF6, Increases IL-8 transcription, Involved in IL-18-mediated signaling pathway, Isoform 2 is defective in its ability to induce IRAK phosphorylation and NF-kappa-B activation and can function as a negative regulator of activation by IL-1 or lipopolysaccharide (LPS), MyD88-mediated signaling in intestinal epithelial cells is crucial for maintenance of gut homeostasis and controls the expression of the antimicrobial lectin REG3G in the small intestine, NOS2/INOS, and IL12A genes, cytokine secretion and the inflammatory response, leading to NF-kappa-B activation, Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response
PurificationPurified by Protein A
Storage conditions 50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA
Excitation emission499nm/519nm
Properties ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 488 has the same range to that of fluorescein isothiocyanate (FITC), Also Alexa Fluor 488 is pH stable, As a result of this photo stability, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, It is distinguished in the FL1 of a FACS-Calibur or FACScan, has a very high photo stability, it has turned into an antibody for fluorescent microscopy and FACS FLOW cytometry, yet the MyD88 Antibody, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate
ConjugationAlexa Fluor
Gene targetMyD88
Short nameMyD88 Antibody
Technique antibodies against human proteins, antibodies for, Antibody
LabelALEXA FLUOR 488
Alternative name ALEXA FLUOR 488, myeloid differentiation primary response 88 (Antibody to)
Alternative techniqueantibodies
Identity 7562
Gene MYD88
Long gene name myeloid differentiation primary response 88
Synonyms gene name myeloid differentiation primary response gene (88)
Locus 3p22, 2
Discovery year 1997-12-23
GenBank acession U84408
Entrez gene record 4615
Pubmed identfication 9013863
RefSeq identity NM_002468
Classification TIR domain containing
Havana BLAST/BLAT OTTHUMG00000131083
Locus Specific Databases LRG_157

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