Name : MyD88 Antibody, ALEXA FLUOR 594
Supplier : BIOSS PRIMARY CONJUGATED ANTIBODIES
Price :332
SKU : GEN6884956265
| Long name | ALEXA FLUOR 594 Conjugated, MyD88 Polyclonal Antibody |
| Also known as | Anti-MyD88 PAb ALEXA FLUOR 594 |
| Category | Conjugated Primary Antibodies |
| Conjugated with | 594, ALEXA FLUOR® |
| Host Organism | Rabbit (Oryctolagus cuniculus) |
| Target Antigen | MyD88 |
| Specificity | This is a highly specific antibody against MyD88 |
| Modification | Unmodified |
| Modification Site | None |
| Clonality | Polyclonal |
| Clone | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Immunogen range | 240-290/296 |
| Subcellular location | Cytoplasm |
| Source | KLH conjugated synthetic peptide derived from mouse MyD88 |
| Gene ID Number | 17874 |
| Swiss Prot | P22366 |
| Tested applications | IF(IHC-P) |
| Recommended dilutions | IF(IHC-P)(1:50-200) |
| Crossreactivity | Mouse, Rat, Human |
| Cross-reactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen | Activates IRF1 resulting in its rapid migration into the nucleus to mediate an efficient induction of IFN-beta, Acts via IRAK1, IRAK2, IRF7 and TRAF6, Increases IL-8 transcription, Involved in IL-18-mediated signaling pathway, Isoform 2 is defective in its ability to induce IRAK phosphorylation and NF-kappa-B activation and can function as a negative regulator of activation by IL-1 or lipopolysaccharide (LPS), MyD88-mediated signaling in intestinal epithelial cells is crucial for maintenance of gut homeostasis and controls the expression of the antimicrobial lectin REG3G in the small intestine, NOS2/INOS, and IL12A genes, cytokine secretion and the inflammatory response, leading to NF-kappa-B activation, Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response |
| Purification | Purified by Protein A |
| Storage conditions | 50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission | 590nm/617nm |
| Properties | ALEXA FLUOR they should be stored frozen at - 24°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation | 594, ALEXA FLUOR®, Alexa Fluor |
| Conjugated | Alexa conjugate 1 |
| Gene target | MyD88 |
| Short name | MyD88 Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Label | ALEXA FLUOR 594 |
| Alternative name | ALEXA FLUOR 594, myeloid differentiation primary response 88 (Antibody to) |
| Alternative technique | antibodies |
| Identity | 7562 |
| Gene | MYD88 |
| Long gene name | myeloid differentiation primary response 88 |
| Synonyms gene name | myeloid differentiation primary response gene (88) |
| Locus | 3p22, 2 |
| Discovery year | 1997-12-23 |
| GenBank acession | U84408 |
| Entrez gene record | 4615 |
| Pubmed identfication | 9013863 |
| RefSeq identity | NM_002468 |
| Classification | TIR domain containing |
| Havana BLAST/BLAT | OTTHUMG00000131083 |
| Locus Specific Databases | LRG_157 |