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MYLIP Antibody

MYLIP Antibody size: 0.1ml 263

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price 263
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long nameMYLIP Primary Polyclonal Antibody
Also known asMYLIP PAb
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenMYLIP
SpecificityThis is a highly specific antibody against MYLIP
Modification(s)None
Modification site(s)Unmodified antibody
ClonalityPolyclonal antibody
Clone numberPolyclonal antibody
Concentration1ug per 1ul
Immunogen range65-103/445
Subcellular locationCell membrane
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human MYLIP
Gene ID number29116
Swiss ProtQ8WY64
Tested Applications IF(IHC-P), IHC-P, WB
Recommended dilutions IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000)
Cross reactivity Mouse, Rat, Human
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen Activity depends on E2 enzymes of the UBE2D family, Acts as a sterol-dependent inhibitor of cellular cholesterol uptake by mediating ubiquitination and subsequent degradation of LDLR, LDLR, Proteasomal degradation of MRLC leads to inhibit neurite outgrowth in presence of NGF by counteracting the stabilization of MRLC by saposin-like protein (CNPY2/MSAP) and reducing CNPY2-stimulated neurite outgrowth, VLDLR and LRP8, E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of myosin regulatory light chain (MRLC)
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names BM-023, BZF1, E3 ubiquitin-protein ligase MYLIP, IDOL, Inducible degrader of the LDL-receptor, MYLIP, Myosin regulatory light chain interacting protein, PP5242, MIR
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene targetMYLIP
Short nameMYLIP Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameMYLIP (Antibody to)
Alternative techniqueantibodies
Identity 21155
Gene MYLIP
Long gene name myosin regulatory light chain interacting protein
Synonyms MIR IDOL
Synonyms name E3 ubiquitin ligase-inducible degrader of the low density lipoprotein receptor
Locus 6p22, 3
Discovery year 2003-11-26
GenBank acession AF187016
Entrez gene record 29116
Pubmed identfication 10593918 11162443 19688294
RefSeq identity NM_013262
Classification FERM domain containing
Havana BLAST/BLAT OTTHUMG00000016405

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