Name : MYLIP Antibody, ALEXA FLUOR 488
Supplier : BIOSS PRIMARY CONJUGATED ANTIBODIES
Price :332
SKU : GEN7877109703
| Long name | ALEXA FLUOR 488 Conjugated, MYLIP Polyclonal Antibody |
| Also known as | Anti-MYLIP PAb ALEXA FLUOR 488 |
| Category | Conjugated Primary Antibodies |
| Conjugated with | 488, ALEXA FLUOR® |
| Host Organism | Rabbit (Oryctolagus cuniculus) |
| Target Antigen | MYLIP |
| Specificity | This is a highly specific antibody against MYLIP |
| Modification | Unmodified |
| Modification Site | None |
| Clonality | Polyclonal |
| Clone | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Immunogen range | 65-103/445 |
| Subcellular location | Cell membrane |
| Source | This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human MYLIP |
| Gene ID Number | 29116 |
| Swiss Prot | Q8WY64 |
| Tested applications | IF(IHC-P) |
| Recommended dilutions | IF(IHC-P)(1:50-200) |
| Crossreactivity | Mouse, Rat, Human |
| Cross-reactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen | Activity depends on E2 enzymes of the UBE2D family, Acts as a sterol-dependent inhibitor of cellular cholesterol uptake by mediating ubiquitination and subsequent degradation of LDLR, LDLR, Proteasomal degradation of MRLC leads to inhibit neurite outgrowth in presence of NGF by counteracting the stabilization of MRLC by saposin-like protein (CNPY2/MSAP) and reducing CNPY2-stimulated neurite outgrowth, VLDLR and LRP8, E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of myosin regulatory light chain (MRLC) |
| Purification | Purified by Protein A |
| Storage conditions | 50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission | 499nm/519nm |
| Synonyms | MIR IDOL |
| Properties | ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 488 has the same range to that of fluorescein isothiocyanate (FITC), Also Alexa Fluor 488 is pH stable, As a result of this photo stability, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, It is distinguished in the FL1 of a FACS-Calibur or FACScan, has a very high photo stability, it has turned into an antibody for fluorescent microscopy and FACS FLOW cytometry, yet the MYLIP Antibody, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation | Alexa Fluor |
| Gene target | MYLIP |
| Short name | MYLIP Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Label | ALEXA FLUOR 488 |
| Alternative name | ALEXA FLUOR 488, MYLIP (Antibody to) |
| Alternative technique | antibodies |
| Identity | 21155 |
| Gene | MYLIP |
| Long gene name | myosin regulatory light chain interacting protein |
| Synonyms name | E3 ubiquitin ligase-inducible degrader of the low density lipoprotein receptor |
| Locus | 6p22, 3 |
| Discovery year | 2003-11-26 |
| GenBank acession | AF187016 |
| Entrez gene record | 29116 |
| Pubmed identfication | 10593918 11162443 19688294 |
| RefSeq identity | NM_013262 |
| Classification | FERM domain containing |
| Havana BLAST/BLAT | OTTHUMG00000016405 |